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5-HT Receptor

5-HT Receptor

货号 产品名 CAS号 信息
CSN12199 Vilazodone 163521-12-8 Vilazodone is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major depression.
CSN23171 Tropanserin 85181-40-4 Tropanserin is a selective 5-HT3 receptor antagonist.
CSN27240 Tianeptine 66981-73-5 Tianeptine is an atypical antidepressant drug. It decreases serotonin's activity and amount in serotonergic synapses of the central nervous system by increasing serotonin reuptake.
CSN12086 Tiamenidine 31428-61-2 Thioridazine is an antipsychotic drug, used in the treatment of schizophrenia and psychosis, shows D4 selectivity or serotonin antagonism.
CSN23197 WAY 629 HCl 57756-44-2 Selective 5-HT2C agonist
CSN23140 Tandospirone HCl 99095-10-0 Selective 5-HT1A partial agonist
CSN23208 Zimelidine 2HCl 60525-15-7 Selective 5-HT uptake inhibitor
CSN23095 SB 215505 162100-15-4 SB215505 is a potent 5-HT2B/2C receptor antagonist (pKi values are 8.3, 7.66 and 6.77 for 5-HT2B, 5-HT2C and 5-HT2A respectively). It Increases wakefulness and motor activity in rats.
CSN23105 SB 699551 864741-95-7 SB 699551 is a selective 5-ht5a receptor antagonist (pKi values are 8.3, < 6.0, < 6.0, < 6.0, < 5.5 and < 5.5 for 5-ht5a, 5-HT1B/D, 5-HT2A, 5-HT2C, 5-HT1A and 5-HT7 receptors respectively).
CSN23096 SB 221284 196965-14-7 SB 221284 is potent, selective 5-HT2C/2B receptor antagonist. SB 221284 are pKi values are 6.4, 7.9 and 8.6 for 5-HT2A, 2B and 2C receptors respectively.
CSN17113 Promethazine HCl 58-33-3 Promethazine HCl is the effective antagonist of the H1 receptor and moderate antagonist of mACh receptor.
CSN23130 SR 57227 HCl 77145-61-0 Potent and selective 5-HT3 agonist
CSN27301 Phenylbiguanide 102-02-3 Phenylbiguanide is a 5-HT3 receptor selective agonist with an EC50 of 3.0±0.1 μM.
CSN18173 Pardoprunox HCl 269718-83-4 Pardoprunox HCl is a partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist and 5-HT1A receptor (pKi = 8.5) full agonist.
CSN27393 Paliperidone palmitate 199739-10-1 Paliperidone palmitate (9-Hydroxyrisperidone palmitate), an atypical long-acting antipsychotic agent, is an ester prodrug of Paliperidone. Paliperidone is a dopamine antagonist and 5-HT2A antagonist of the atypical antipsychotic class. Paliperidone palmitate shows efficacy against schizophrenia.
CSN27188 p-MPPI HCl 220643-77-6 p-MPPI is a novel 5-HT Receptor 1A receptor antagonist. It produced a significant and dose-related anxiolytic profile in male mice.
CSN27303 Org-12962   132834-56-1 Org-12962 is a potent, selective and orally active 5-HT2C receptor agonist with a pEC50 value of 7.01. Org-12962 also exhibits high effacy for the 5-HT2A and 5-HT2B receptor with pEC50s of 6.38 and 6.28, respectively.Org-12962 displays antiaversive effects in a rat model of panic-like anxiety.
CSN26151 LY344864 racemate 186543-64-6 LY344864 racemate is the racemate form of LY344864. LY344864 is a selective receptor agonist with an affinity of 6 nM (Ki) at the recently cloned 5-HT1F receptor.
CSN14586 Galanolactone 115753-79-2 Galanolactone, a natural product isolated and purified from the rhizomes of Zingiber officinale Roscoe with cytotoxic activity, has anti-5-HT effect, a diterpenoid isolated from ginger, is related to antagonism of 5-HT3 receptors, exerts anti-obesity effect through down regulation of adipogenic transcription factors and adipogenic marker genes, and inhibits nitric oxide production with IC(50) values ranging from 5.5 to 28.5 μM.
CSN25658 Elopiprazole 115464-77-2 Elopiprazole is an antipsychotic drug of the phenylpiperazine class.
CSN27302 Dehydroaripiprazole   129722-25-4 Dehydroaripiprazole (OPC-14857) is an active metabolite of Aripiprazole. Aripiprazole is an antipsychotic agent and is metabolized by CYP3A4 and CYP2D6 forming mainly Dehydroaripiprazole. Dehydroaripiprazole has with antipsychotic activity equivalent to Aripiprazole.
CSN23783 AVN492 1220646-23-0 AVN492 is a selective antagonist of 5-HT6R with Ki of 91 pM.
CSN24980 5-Methoxytryptamine 608-07-1 5-Methoxytryptamine is a tryptamine derivative that acts as a full agonist at the 5-HT1, 5-HT2, 5-HT4, 5-HT6, and 5-HT7 receptors.
CSN23078 RS 67506 HCl 168986-61-6 5-HT4 partial agonist
CSN23074 RS 23597-190 HCl 149719-06-2 5-HT4 antagonist
CSN23076 RS 39604 HCl 167710-87-4 5-HT4 antagonist
CSN23090 SB 200646 HCl 143797-62-0 5-HT2C/2B antagonist
CSN23080 RU 24969 Hemisuccinate 66611-27-6 5-HT1A and 5-HT1B agonist
CSN27304 2-Methyl-5-HT 78263-90-8 2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT is shown to display anti-depressive-like effects.
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