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5-HT Receptor

5-HT Receptor

货号 产品名 CAS号 信息
CSN26541 ZK756326 2HCl 1780259-94-0 ZK-756326 is a potent, selective and non-peptide CCR8 chemokine receptor agonist. ZK 756326 inhibited the binding of the CCR8 ligand I-309 (CCL1), with an IC(50) value of 1.8 muM. ZK 756326 was a full agonist of CCR8, dose-responsively eliciting an increase in intracellular calcium and cross-desensitizing the response of the receptor to CCL1.
CSN12086 Tiamenidine 31428-61-2 Thioridazine is an antipsychotic drug, used in the treatment of schizophrenia and psychosis, shows D4 selectivity or serotonin antagonism.
CSN21856 Tertatolol 83688-84-0 Tertatolol is a potent antagonist of beta-adrenoceptor and 5-HT receptor, with unique renal vasodilatatory effects.
CSN11918 Sertindole 106516-24-9 Sertindole, a neuroleptic, is one of the antipsychotic medications available, with a high affinity for dopamine D2, serotonin 5-HT2A, 5-HT2C, and α1-adrenergic receptors.
CSN21989 SB-224289 HCl 180084-26-8 SB-224289 hydrochloride is a selective 5-HT1B receptor antagonist, with anxiolytic effect.
CSN26568 SB-200646 143797-63-1 SB-200646 is the first selective 5-HT2B/2C over 5-HT2A receptor antagonist with pKi values of 7.5, 6.9 and 5.2 for 5-HT2B, 5-HT2C and 5-HT2A, respectively. SB-200646 is orally active and has electrophysiological and anxiolytic properties in vivo[1][2].
CSN13491 RS 127445 199864-87-4 RS 127445 is a potent and selective antagonist at 5-HT2B receptor with pKi value of 9.5.
CSN33114 Roluperidone 359625-79-9 Roluperidone is a 5-HT2A and sigma 2 receptor antagonist.
CSN17113 Promethazine HCl 58-33-3 Promethazine HCl is the effective antagonist of the H1 receptor and moderate antagonist of mACh receptor.
CSN27301 Phenylbiguanide 102-02-3 Phenylbiguanide is a 5-HT3 receptor selective agonist with an EC50 of 3.0±0.1 μM.
CSN18173 Pardoprunox HCl 269718-83-4 Pardoprunox HCl is a partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist and 5-HT1A receptor (pKi = 8.5) full agonist.
CSN21782 Pancopride 121650-80-4 Pancopride is a selective antagonist of 5-HT3 receptor.
CSN27303 Org-12962   132834-56-1 Org-12962 is a potent, selective and orally active 5-HT2C receptor agonist with a pEC50 value of 7.01. Org-12962 also exhibits high effacy for the 5-HT2A and 5-HT2B receptor with pEC50s of 6.38 and 6.28, respectively.Org-12962 displays antiaversive effects in a rat model of panic-like anxiety.
CSN11590 Nuciferine 475-83-2 Nuciferine is naturally occuring alkaloid found in the plants Nymphaea caerulea and Nelumbo nucifera as a potent inverse agonist at human 5-HT7 receptor.
CSN23228 NPS ALX Compound 4a 2HCl 1781934-44-8 NPS ALX Compound 4a dihydrochloride is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM .
CSN26151 LY344864 racemate 186543-64-6 LY344864 racemate is the racemate form of LY344864. LY344864 is a selective receptor agonist with an affinity of 6 nM (Ki) at the recently cloned 5-HT1F receptor.
CSN21712 Lintopride 107429-63-0 Lintopride is an antagonist of 5HT4 receptor and moderate antagonist of 5HT3.
CSN21711 Lidanserin 73725-85-6 Lidanserin is antagonist of 5-HT2A and α1-adrenergic receptor.
CSN26570 Lesopitron 2HCl 132449-89-9 Lesopitron dihydrochloride is a 5-HT1A receptor agonist potentially for the treatment of generalized anxiety disorder.
CSN12998 Lamotrigine 84057-84-1 Lamotrigine is a member of the sodium channel blocking class of antiepileptic drugs which can block L-, N-, and P-type calcium channels and has weak 5-HT3 receptor inhibition.
CSN21695 Irindalone 96478-43-2 Irindalone is an antagonist of serotonin 5-HT2 receptor.
CSN27680 GR 125743 148547-33-5 GR 125743 is a novel 5-HT1B/1D receptor antagonist.
CSN26499 Fiduxosin free base 208993-54-8 Fiduxosin is an alpha(1)-adrenoceptor antagonist with higher affinity for alpha(1A)-adrenoceptors and for alpha(1D)-adrenoceptors than for alpha(1B)-adrenoceptors.
CSN21600 Deramciclane 120444-71-5 Deramciclane is an antagonist of 5-HT2A and inverse agonist of 5-HT2C receptor. It also functions as a GABA reuptake inhibitor.
CSN21594 Dazopride 70181-03-2 Dazopride is an antiemetic agent which acts as a 5-HT3 receptor antagonist and 5-HT4 receptor agonist.
CSN33115 CYR-101 HCl 2H2O 1937215-88-7 CYR-101 hydrochloride dihydrate is a 5-HT2A and sigma 2 receptor antagonist.
CSN32884 AVN-211 1173103-84-8 AVN-211 is a Novel and Highly Selective 5-HT6 Receptor Small Molecule Antagonist for the Treatment of Alzheimer's Disease.
CSN33129 R-Azasetron 2025360-90-9 Arazasetron is an antiemetic which acts as a 5-HT3 receptor antagonist, pKi = 9.27.
CSN33130 R-Arazasetron Besylate 2025360-91-0 Arazasetron besylate is an antiemetic which acts as a 5-HT3 receptor antagonist, pKi = 9.27.
CSN21450 Abaperidone 183849-43-6 Abaperidone is an antagonist of 5-HT2A receptor and dopamine D2 receptor with IC50s of 6.2 and 17 nM respectively.
CSN24609 3-MPPI 133399-65-2 3-MPPI is a very potent ligand for α1 sites and regulates smooth muscle contraction. The pKi values for α1B, α1D, α1A adrenoceptors are 8.74, 9.44, 9.57 respectively. It also binds to 5-HT1A sites (Ki = 50 nM).
CSN21566 (Z)-Thiothixene 3313-26-6 (Z)-Thiothixene is serotonergic receptor antagonist.
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