| CSN10004 |
Cladribine |
4291-63-8 |
Cladribine is an adenosine deaminase inhibitor used to treat hairy cell leukemia and multiple sclerosis. For U266, RPMI8226, and MM1.S cells, its IC50 |
| CSN10240 |
Aliskiren |
173334-57-1 |
Aliskiren is a renin inhibitor with IC50 of 1.5 nM. |
| CSN10349 |
Atazanavir |
198904-31-3 |
Atazanavir is a protease inhibitor used as an antiretroviral medication to treat and prevent HIV/AIDS. |
| CSN10369 |
Azilsartan |
147403-03-0 |
Azilsartan is an orally available angiotensin II type 1 (AT1) receptor antagonist with IC50 value of 2.6 nM. |
| CSN10496 |
Ambrisentan |
177036-94-1 |
Ambrisentan is an oral, once-daily endothelin receptor antagonist that is selective for the endothelin type A receptor (IC50s = 0.251, 0.316, 0.398, 2 |
| CSN10538 |
Caffeic Acid Phenethyl Ester |
104594-70-9 |
Caffeic acid phenethyl ester, a natural product isolated and purified from the barks of Cinnamomum cassia Presl, is a potent and specific inhibitor of |
| CSN10852 |
DMXAA |
117570-53-3 |
DMXAA is an apoptosis inducer with anti-vascular activity. It is mSTING agonist, selective for mouse STING over human STING. It Induces IFN-β and cyto |
| CSN10931 |
Erlotinib |
183321-74-6 |
Erlotinib is an EGFR inhibitor with IC50 of 2 nM, > 1000-fold more sensitive for EGFR than human c-Src or v-Abl. |
| CSN11084 |
Gefitinib |
184475-35-2 |
Gefitinibis an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respe |
| CSN11131 |
GW9662 |
22978-25-2 |
GW9662 selectively antagonizes PPARγ with IC50 of 3.3 nM. It can inhibit the growth of mammary cancer cells. |
| CSN11187 |
GM6001 |
142880-36-2 |
GM6001 is a broad spectrum MMPs inhibitor for MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-12, MMP-14, and MMP-26 with Ki of 0.4 nM, 0.5 nM, 27 nM, 3 |
| CSN11190 |
Imatinib |
152459-95-5 |
Imatinib is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM in cell-free or cell-based assays, respectively. |
| CSN11280 |
Lenalidomide |
191732-72-6 |
Lenalidomide, a analog of thalidomide, is TNF-α secretion inhibitor with IC50 of 13 nM. |
| CSN11339 |
Lubiprostone |
136790-76-6 |
Lubiprostone is an ClC-2 chloride channel activator used in the treatment of idiopathic chronic constipation. |
| CSN11455 |
Montelukast Sodium |
151767-02-1 |
Montelukast Sodium is a potent, selective and competitive LTR1 antagonist with IC50 value < 5 nM, possesssing anti-inflammatory and bronchodilating ac |
| CSN11667 |
Pemetrexed |
137281-23-3 |
Pemetrexed is an antifolate and antimetabolite for TS(thymidylate synthase), DHFR(dihydrofolate reductase) and GARFT(glycinamide ribonucleotide formyl |
| CSN11857 |
Roflumilast |
162401-32-3 |
Roflumilast is a selective and long-acting inhibitor of PDE-4 with IC50 of 0.8 nM. |
| CSN11862 |
Roscovitine |
186692-46-6 |
Roscovitine is a potent and selective CDK inhibitor for Cdc2, CDK2 and CDK5 with IC50 of 0.65 μM, 0.7 μM and 0.16 μM and shows little effect on CDK4/6 |
| CSN11899 |
SB-203580 |
152121-47-6 |
SB-203580 is a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM. |
| CSN12170 |
Tyrphostin AG 879 |
148741-30-4 |
Tyrphostin AG 879 potently inhibits HER2/ErbB2 with IC50 of 1 μM, 100- and 500-fold higher selective to ErbB2 than PDGFR and EGFR. |
| CSN12304 |
BSI-201 |
160003-66-7 |
BSI-201 is a PARP1 inhibitor with demonstrated effectiveness in triple-negative breast cancer (TNBC). |
| CSN12327 |
Pixantrone Dimaleate |
144675-97-8 |
Pixantrone dimaleate is a topoisomerase II inhibitor and DNA intercalator, with anti-tumor activity. Pixantrone dimaleate is an experimental antineopl |
| CSN12330 |
Piceatannol |
10083-24-6 |
Piceatannol, a natural stilbene, is selective Syk inhibitor extracted from the rhizomes of Polygonum cuspidatum Sieb. et Zucc.. |
| CSN12357 |
PD153035 |
153436-54-5 |
PD153035 is EGFR inhibitor with Ki and IC50 of 5.2 pM and 29 pM and could rapidly suppress autophosphorylation of EGFR. |
| CSN12358 |
AG-1478 |
153436-53-4 |
AG-1478 selectively inhibits EGFR with IC50 of 3 nM in cell-free assay. |
| CSN12447 |
Fondaparinux Sodium |
114870-03-0 |
Fondaparinux sodium is a pentasaccharide inhibitor of antithrombin-dependent factor Xa (IC50 = 40 nM). It can bind to antithrombin III. |
| CSN12489 |
Pioglitazone HCl |
112529-15-4 |
Pioglitazone HCl is a selective agonist of PPARγ with EC50 of 0.93 μM which is used to treat diabetes. |
| CSN12500 |
Combretastatin A4 |
117048-59-6 |
Combretastatin A4 is a tubulin polymerization inhibitor with Kd value of 0.4 μM for binding to β-tubulin. |
| CSN12559 |
Tenofovir |
147127-20-6 |
Tenofovir is an antiretroviral drug known as nucleotide analogue reverse transcriptase inhibitors (NRTIs), which block reverse transcriptase, a crucia |
| CSN12570 |
Rosiglitazone Maleate |
155141-29-0 |
Rosiglitazone maleate is the maleate form of rosiglitazone which is a high-affinity selective agonist of the peroxisome proliferator-activated recepto |
| CSN12700 |
PD153035 HCl |
183322-45-4 |
PD153035 HCl is an reversible inhibitor of EGFR with Ki and IC50 of 5.2 pM and 29 pM. |
| CSN12964 |
Cabazitaxel |
183133-96-2 |
Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity. Cabazitaxel exerts it |
| CSN13185 |
Pomalidomide |
19171-19-8 |
Pomalidomide can inhibit LPS-induced TNF-α release with IC50 of 13 nM in PBMCs. |
| CSN13562 |
Triapine |
143621-35-6 |
Triapine is a ribonucleotide reductase inhibitor and a CDK inhibtor. |
| CSN16276 |
PF-06840003 |
198474-05-4 |
PF-06840003 is a highly selective orally bioavailable IDO-1 inhibitor with IC50 of 0.41 μM. |
| CSN16424 |
Licochalcone A |
58749-22-7 |
Licochalcone A, an estrogenic flavanoid, can be an inhibitor of p-glycoprotein and has anti-inflammatory actions. |
| CSN16694 |
Metformin HCl |
1115-70-4 |
Metformin HCl, a widely used anti-diabetic drug has potential efficacy as an anti-cancer drug, decreasing hyperglycemia in hepatocytes primarily by su |
| CSN16698 |
Alendronate Sodium Trihydrate |
121268-17-5 |
Alendronate Sodium Trihydrate is an inhibitor of farnesyl diphosphate synthase with IC50 of 460 nM. It is used to treat osteoporosis. |
| CSN16708 |
Calcifediol |
19356-17-3 |
Calcifediol is an active metabolite of vitamin D. It can inhibit the secretion of parathyroid hormone with 2 nM and commonly used as an indicator of b |
| CSN16716 |
Everolimus |
159351-69-6 |
Everolimus is a mTOR inhibitor of FKBP12 with IC50 of 1.6-2.4 nM. |
| CSN16720 |
Fingolimod HCl |
162359-56-0 |
Fingolimod HCl is a S1P antagonist with IC50 of 0.033 nM. |
| CSN16725 |
Erlotinib HCl |
183319-69-9 |
Erlotinib HCl is a directly acting inhibitor of human EGFR tyrosine kinase with an IC50 of 2 nM. |
| CSN19413 |
Polydatin |
27208-80-6 |
Polydatin, extracted from the roots ofPolygonum cuspidatumSieb, a widely used traditional Chinese remedies, possesses anti-inflammatory activity in se |
| CSN19473 |
Bexarotene |
153559-49-0 |
Bexarotene is a selective agonist of RXRβ (IC50 = 24 nM), RXRγ (IC50 = 25 nM) and RXRα (IC50 = 33 nM) with antineoplastic activity. |
| CSN19160 |
H 89 2HCl |
130964-39-5 |
H 89 2HCl is a potent and selective inhibitor of cyclic AMP-dependent protein kinase (protein kinase A) with IC50 of 48 nM. It also shows weak inhibit |
| CSN16987 |
ABT-751 |
141430-65-1 |
ABT-751 can inhibit microtubule polymerization through binding to β-tubulin on the colchine site. |
| CSN12943 |
Marimastat |
154039-60-8 |
Marimastat is a competitive and broad-spectrum MMP inhibitor with IC50 values of 3, 5, 6, 9 and 13 nM for MMP-9, MMP-1, MMP-2, MMP-14 and MMP-7, respe |
| CSN10894 |
Elacridar |
143664-11-3 |
Elacridar is a P-glycoprotein inhibitor, and has been used both in vitro and in vivo as a tool inhibitor of P-glycoprotein (Pgp) to investigate the ro |
| CSN11329 |
Lopinavir |
192725-17-0 |
Lopinavir is an antiretroviral of the protease inhibitor class, as well as an inhibitor of P-Glycoprotein, Cytochrome P450 3A and Organic Anion Transp |
| CSN13587 |
Ritonavir |
155213-67-5 |
Ritonavir is both an HIV protease inhibitor and a Cytochrome P450 3A inhibitor. |
400-920-2911
上海市杨浦区翔殷路128号1号楼101
