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货号 产品名称 CAS号 简介
CSN20392 Benzyl ((2S)-3-methyl-1-oxo-1-((1-oxo-3-phenylpropan-2-yl)amino)butan-2-yl)carbamate  88191-84-8 MDL28170 is a potent, selective inhibitor of calpain and cathepsin B (Ki values are 10 and 25 nM respectively) that does not inhibit trypsin-like seri
CSN26140 N-(3-Benzylthiazol-2(3H)-ylidene)-1H-pyrrolo[2,3-b]pyridine-3-carboxamide  1424635-83-5 TRULI is an ATP-competitive inhibitor of Lats kinases. It is a potent, non-toxic, and reversible inhibitor of Hippo signaling which causes Yap-depende
CSN26180 6-((Naphthalen-1-ylmethyl)thio)-7H-purine  313984-77-9 PU-02 is an antagonist of serotonin (5-HT) receptor subtype 5-HT3.
CSN27205 4-((4-Methoxyphenyl)diazenyl)-1H-pyrazole-3,5-diamine  6975-75-3 ILK-IN-3 is an integrin linked kinase inhibitor.
CSN27206 9-(2,4-Dihydroxyphenyl)-3,3,6,6-tetramethyl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-dione  117593-36-9 CIL56 is a inducer of regulated, non-apoptotic cell death. It is a lead compound of FIN56,
CSN27211 Bis(morpholinothiocarbonyl) disulfide  729-46-4 JX06 is a selective covalent PDK1 inhibitor with IC50 values of 49, 101 and 313nM for PDK-1, PDK-2 and PDK-3, respectively.
CSN27238 2-Methyl-2-(4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy)propanoic acid  3771-19-5 Nafenopin is a peroxisome proliferator that is used to promote liver tumors. It has been used as an antihyperlipoproteinemic agent.
CSN27244 (2R,3S,5R)-5-(6-Amino-9H-purin-9-yl)-2-methyltetrahydrofuran-3-ol  6698-26-6 2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor via binding the P-site with an IC50 of 3 µM . 2',5'-Dideoxyadenosine
CSN27600 1-Methyl-8-(4-(quinolin-2-ylmethoxy)phenoxy)-4,5-dihydro-1H-thieno[3,4-g]indazole-6-carboxamide  364762-86-7 TD-198946, a thienoindazole derivative, is a potent chondrogenic agent.
CSN26189 4-(1-(4-(2-(Dimethylamino)ethoxy)phenyl)-2-phenylbut-1-en-1-yl)phenol  68392-35-8 Afimoxifene is the active metabolite of tamoxifen and a selective estrogen receptor (ER) modulator that is widely used in the therapeutic and chemopre
CSN27722 2-(4-(3-((4-Oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)nicotinonitrile  1825345-33-2 AZ9482 is a PARP inhibitor with IC50 values of 1, 1, 46, 640, 9, and 160nM for PARP1, -2, -3, -6, TNKS1/PARP5a, and TNKS2, respectively.
CSN27723 4-Ethoxy-N-(5-nitrothiazol-2-yl)benzamide  312608-54-1 MID-1 is a MG53-IRS-1 interaction disruptor. It abolished MG53-mediated IRS-1 ubiquitination and degradation, as well as sensitized insulin signaling
CSN27735 N-(3-Methoxybenzyl)-5-(4-methoxyphenyl)-1-methyl-1H-imidazol-2-amine  827327-28-6 MALAT1-IN-1 is a potent and specific Malat1 (Metastasis-associated lung adenocarcinoma transcript 1) inhibitor.
CSN27743 3-((4-(Methyl(4-(3-(4-(trifluoromethoxy)phenyl)ureido)phenyl)amino)pyrimidin-2-yl)amino)benzenesulfonamide  579515-63-2 GW806742X is an ATP mimetic MLKL inhibitor with Kd value of 9.3μM, and a VEGFR2 inhibitor with IC50 value of 2nM.
CSN27773 3-Bromo-N'-(1-(2,4-dihydroxyphenyl)ethylidene)-4-methylbenzohydrazide  468747-17-3 mTOR inhibitor-1 is an ATP-competitive inhibitor of mTOR. It suppressed A549 cell proliferation and induced autophagy.
CSN27768 1-(4-(2H-Tetrazol-5-yl)butyl)-4-(5H-dibenzo[a,d][7]annulen-5-ylidene)piperidine  162640-98-4 AT 56 is an orally active L-PGDS inhibitor with IC50 value of 95μM. It inhibits the production of PGD2 from PGH2 in vitro, with no effect on PG
CSN27779 (E)-6-Fluoro-2-(2-(5-nitrofuran-2-yl)vinyl)-3-phenylquinazolin-4(3H)-one  2374285-52-4 CEBPα inducer 1 is a potent inducer of C/EBPα and myeloid differentiation.
CSN27841 (Z)-5-(4-Hydroxybenzylidene)-3-isobutyl-2-thioxothiazolidin-4-one  1558598-41-6 PFM 01 is a MRE11 endonuclease inhibitor which can prevent double-stranded break resection. It enhances NHEJ and reduces homologous recombination.
CSN27839 4-Cyano-N-cyclopropyl-N-(thiophen-2-ylmethyl)benzamide  1210906-48-1 NSD2-PWWP1 antagonist 3f can bind to the NSD2-PWWP1 domain with Kd value of 3.4μM and abrogates histone H3K36me2 binding to the PWWP1 domain in cells.
CSN27842 5-(5-Bromo-2-hydroxy-3-methoxybenzylidene)-2-thioxoimidazolidin-4-one  292168-90-2 IT-603 is a c-Rel inhibitor with IC50 value of 3μM.
CSN27837 3,6-Diamino-9-(2-(methoxycarbonyl)phenyl)xanthylium chloride  62669-70-9
CSN27843 9-(2,4-Disulfophenyl)-2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium inner salt  60311-02-6 Sulforhodamine 101, a fluorescent dye (Ex ~586nm, Em ~606nm), is a selective astrocyte marker.
CSN27847 4-((4-(2,4-Dichlorophenyl)-3-ethylthiazol-2(3H)-ylidene)amino)benzenesulfonamide  2561476-24-0 EMAC10101d is a potent and selective Carbonic Anhydrase II inhibitor.
CSN27848 5-(5-(6-(4-Acetylpiperazin-1-yl)-3-nitropyridin-2-yl)-2-fluorobenzylidene)thiazolidine-2,4-dione  853953-65-8 GW604714X is a highly specific MPC (mitochondrial pyruvate carrier) inhibitor with Ki value<0.1nM.
CSN27850 N-(Benzo[d][1,3]dioxol-5-yl(5-chloro-8-hydroxyquinolin-7-yl)methyl)butyramide  423145-35-1 YUM70 is a GRP78 inhibitor with IC50 value of 1.5μM and resulted in ER stress-mediated apoptosis. It inhibited pancreatic cancer cell growth in vit
CSN27849 (S)-N-(3-(1-((6-(3,4-Dimethoxyphenyl)pyrazin-2-yl)amino)ethyl)phenyl)-5-methylnicotinamide  1619931-27-9 Seralutinib is a potent and novel inhaled PDGFR inhibitor, used in the study for pulmonary arterial hypertension.
CSN27868 (S)-N-(4-(tert-Butyl)phenyl)-N-(2-(tert-butylamino)-2-oxo-1-(pyridin-3-yl)ethyl)furan-2-carboxamide  1417700-12-9 16-(S)-ML188 is a non-covalent SARS-CoV 3CLpro inhibitor with good enzyme and antiviral inhibitory activity.
CSN27872 rel-N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)-5-((3aR,4R,6aS)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide  2193462-87-0 Melatonin Biotin is compound conjuncted melatonin with biotin.
CSN27873 N-(1-(Dimethylamino)propan-2-yl)-2-(pyridin-4-yl)-1H-benzo[d]imidazole-7-carboxamide  2438721-44-7 ChX710 can boost cellular response to cytosolic DNA via STING. It efficiently primed cellular response to transfected plasmid DNA as assessed by poten
CSN28337 5-((2S,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione  1445-07-4 Pseudouridine is a modified nucleoside.
CSN27986 (R)-2,3-Bis(oleoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate  4235-95-4 1,2-DOPC is a phospholipid utilized for liposome production.
CSN28422 2-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one  724711-21-1 MK2 Inhibitor III is a potent and selective MK-2 inhibitor with IC50 value of 8.5nM.
CSN28421 2-(((5-Bromothiophen-2-yl)methylene)amino)benzamide  304456-62-0 MDK6620 is a potent and selective IMP1 inhibitor by inhibiting IMP1 binding to c-Myc mRNA with IC50 value of 5μM. It downregulates several mRNA transc
CSN28430 3-((3-(N-Cyclopropylsulfamoyl)-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)-5-(3,5-difluorophenoxy)benzoic acid  1445879-21-9 GSK2837808A is a potent and selective LDHA and LDHB inhibitor with IC50 values of 2.6nM and 43nM for LDHA and LDHB, respectively. It reduces glucose u
CSN28431 3-(2-Chloro-6-methylphenyl)-7-((2-methoxy-4-(1-methylpiperidin-4-yl)phenyl)amino)-1-(5-methoxypyridin-2-yl)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one  1936529-65-5 YKL-05-099 is a selective SIK inhibitor with IC50 values of 10 nM, 40 nM and 30 nM for SIK1, SIK2 and SIK3, respectively.
CSN26245 N-(2-Oxo-2-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)ethyl)-[1,1'-biphenyl]-4-carboxamide  850467-66-2 TAO Kinase inhibitor 1 is a selective, ATP-competitive thousand-and-one amino acid kinases (TAOK) inhibitor with IC50s of 11 to 15 nM for TAOK1 and 2,
CSN28747 ((4-Hydroxybutyl)azanediyl)bis(hexane-6,1-diyl) bis(2-hexyldecanoate)  2036272-55-4 ALC-0315, a cationic lipid, is a potent siRNA delivery vehicle. It can be used to form LNPs.
CSN28763 2-(3-(3-((5-Ethyl-4'-fluoro-2-hydroxy-[1,1'-biphenyl]-4-yl)oxy)propoxy)-2-propylphenoxy)benzoic acid  161172-51-6 LY293111 is a potent LTB4 receptor antagonist with IC50 values of 17.6nM and 6.3nM for inhibition of the specific binding of radiolabeled-LTB4 to isol
CSN28765 N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3-methyl-1-phenyl-1H-thieno[2,3-c]pyrazole-5-carboxamide  306959-01-3 MYLS22 is a first-in-class small molecule-specific OPA1 inhibitor which inhibits tumor angiogenesis, impacts tumor growth and metastatization dependen
CSN28769 tert-Butyl ((S)-5-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-phenylpropanamido)-6-((4-(hydroxymethyl)phenyl)amino)-6-oxohexyl)carbamate  756487-18-0 TKN8718 is a hydrolyzable ADC linker.
CSN28768 (9H-Fluoren-9-yl)methyl ((S)-1-(((S)-6-((tert-butoxycarbonyl)amino)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxohexan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate  206133-42-8 Fmoc-Phe-Lys(Boc)-PAB is a hydrolyzable ADC linker.
CSN28771 (2R,3R,4S,5R)-2-(7-Amino-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol  10299-44-2 8-Azaadenosine is an ADAR1inhibitor.
CSN28783 1,1'-(2,2-Dimethylpropane-1,3-diyl)bis(3,4-dichloro-1H-pyrrole-2,5-dione)  203115-63-3 NSC 617145 is a WRN helicase inhibitor with IC50 value of 250nM.
CSN28782 (R)-N-(5-(3-Hydroxypyrrolidin-1-yl)-2-morpholinooxazolo[4,5-b]pyridin-6-yl)-2-(2-methylpyridin-4-yl)oxazole-4-carboxamide  1801344-14-8 CA-4948 is a selective and orally bioavailable IRAK4 Inhibitor. It exhibited desirable ADME and PK profiles including good oral bioavailability in mic
CSN28781 N2-(2-Ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl)-6-methyl-N8-neopentylpyrido[3,4-d]pyrimidine-2,8-diamine  1578245-44-9 BOS172722 is clinical candidate Mps1 inhibitor with IC50 value of 11nM.
CSN28785 (1-(6-((5-(4-(Dimethylamino)piperidin-1-yl)pyridin-2-yl)amino)-2-((4-fluorophenyl)amino)pyrido[3,4-d]pyrimidin-4-yl)piperidin-4-yl)methanol  2225887-26-1 EGFR-IN-5 is an inhibitor of EGFR with IC50 values of 10.4 nM, 1.1 nM, 34 nM and 7.2 nM for EGFR, EGFRL858R, EGFRL858R/T790M, and EGFRL858R/T790M/C797
CSN29557 5-Amino-2-(2,6-diisopropylphenyl)isoindoline-1,3-dione  100823-03-8 TC11 is a potent inhibitor of tumor cell proliferation and an inducer of apoptosis via activation of caspase-3, 8 and 9.
CSN29564 N-(3-(4-Fluorophenylsulfonamido)-4-methoxyphenyl)-[1,1'-biphenyl]-4-carboxamide  727699-84-5 DUN99845 was reported as a STING inhbiitor, which inhibited the activation of the STING signal pathway and to prevent or treat a STING-​mediated disea
CSN29561 7-(4-(tert-Butyl)benzyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione  333415-38-6 VU0071063 can activate native Kir6.2/SUR1 channels, thereby inhibiting glucose-stimulated calcium entry in isolated mouse pancreatic β cells.
CSN29565 N-(3-(4-Fluorophenylsulfonamido)-4-hydroxyphenyl)-[1,1'-biphenyl]-4-carboxamide  2249435-90-1 SN-011 is a STING inhibitor, which inhibited the activation of the STING signal pathway and to prevent or treat a STING-​mediated disease. SN-011 is a
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