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Gli

Gli

货号 产品名 CAS号 信息
CSN11904 Sclareolide 564-20-5 Sclareolide is a sesquiterpene lactone natural product derived from various plant sources including Salvia sclarea, Salvia yosgadensis, and cigar tobacco, which may enhance gemcitabine‑induced cell death through mediating the NICD and Gli1 pathways in gemcitabine‑resistant human pancreatic cancer.
CSN15750 HhAntag 496794-70-8 HhAntag is a small molecule inhibitor of GLI1-mediated transcription, an essential down-stream element of the Hedgehog (Hh) pathway, and is an antitumor agent.
CSN15989 2,2'-((2-(Pyridin-4-yl)dihydropyrimidine-1,3(2H,4H)-diyl)bis(methylene))bis(N,N-dimethylaniline) 500579-04-4 GANT61 is an inhibitor for GLI1 as well as GLI2-induced transcription, inhibits hedgehog with IC50 of 5 μM in GLI1 expressing HEK293T cell, and displays selectivity over other pathways.
CSN18697 4,4',4'',4'''-(Thiophene-2,3,4,5-tetrayl)tetrapyridine 64048-12-0 GANT 58 is a potent Gli antagonist that inhibits GLI1-induced transcription (IC50 = 5 μM).
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