欢迎来到CSNpharm！产品仅用于科研！

400-920-2911 sales@csnpharm.cn

NEW 新产品
0

AChE

AChE

货号 产品名 CAS号 信息
CSN12179 Valethamate bromide 90-22-2 Valethamate bromide is generally used as an anticholinergic agent.
CSN12024 1,2,3,4-Tetrahydroacridin-9-amine hydrochloride 1684-40-8 Tacrine HCl is a parasympathomimetic reversible cholinesterase inhibitor.
CSN15659 Skimmianine 83-95-4 Skimmianin, a natural product isolated and purified from the herbs of Skimmia japonica, is an inhibitor against the Leishmania APRT enzyme and a strong acetylcholinesterase (AChE) inhibitor, and has a selective inhibitory effect on the 5-hydroxytryptamine-induced vasopressor responses of rats.
CSN11851 (S)-3-(1-(Dimethylamino)ethyl)phenyl ethyl(methyl)carbamate 123441-03-2 Rivastigmine is a acetylcholinesterase inhibitor with IC50 value of 5.5 μM for cholinesterase, used for the treatment of mild to moderate Alzheimer's disease and Parkinson's disease.
CSN11807 Pyridostigmine bromide 101-26-8 Pyridostigmine Bromide is a reversible cholinesterase inhibitor to treat myasthenia gravis.
CSN14156 Pseudopalmatine 19716-66-6 Pseudocolumbamine is a natural product isolated and purified from the herbs of Tinospora sinensis with antiplasmodial activity ,it's also a AChE inhibitor with IC50 of 1.8 μM.
CSN17059 Pralidoxime chloride 51-15-0 Pralidoxime chloride is an AChE reactivator, used as an antidote to organophosphate pesticides and chemicals.
CSN22325 Buntanetap 116839-68-0 Posiphen is a selective cholinesterase noncompetitive inhibitor with an IC50 of 45.3 μM.
CSN24045 Pitofenone HCl 1248-42-6 Pitofenone hydrochloride, a spasmolytic compound, inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and from electric eel with Kis of 36 and 45 μM, respectively.
CSN20476 Pitofenone 54063-52-4 Pitofenone an AChE inhibitor with Ki values of 36 and 45 μM for bovine erythrocyte and electric eel enzyme, which shows anti-spasmodic activity in combination with Fenpiverinium and Diclofenac.
CSN19869 Picfeltarraenin IA 97230-47-2 Picfeltarraenin IA, a natural product isolated and purified from the herbs of Picria felterrae Lour., is a stronger AChE inhibitor than the known AChE inhibitor Tacrine, a potential PI3K and epidermal growth factor receptor (EGFR ) inhibitor with anti-inflammatory activity, and acts as an inhibitor on both the classical and alternative pathways of the complement system.
CSN14039 N-p-trans-Coumaroyltyramine 36417-86-4 N-p-trans-Coumaroyltyramine, a natural product isolated and purified from the herbs of Exochorda racemosa, is an α-glucosidase inhibitor(Ki = 840 nM in yeast) and an AChE inhibitor (IC50 = 34.5 mg/mL/122 mM), exhibits potent inhibition of cell proliferation, platelet aggregation, and shows antioxidant activity.
CSN15252 Lucidadiol 252351-95-4 Lucidadiol is a natural product isolated and purified from the herbs of fungus Ganoderma pfeifferi with inhibitory activity against acetylcholinesterase (AChE) with the percentage inhibition at 100 uM, butyrylcholinesterase-inhibitory activity at concentrations up to 200 uM, and antiviral activity against influenza virus type A and HSV type 1.
CSN16680 topride HCl 122892-31-3 Itopride HCl is a D2 antagonist and an AChE inhibitor with an IC50 value of 2.04±0.27 μM. It is a prokinetic benzamide derivative unlike domperidone.
CSN19925 7,2-Dihydroxy-3,4-Dimethoxyisoflavan 52250-35-8 Isomucronulatol, a natural product isolated and purified from the roots of Astragalus membranaceus, exhibits significant inhibitory effects on LPS-induced IL-6 and IL-12 p40 production, with IC 50 values ranging from 2.7 to 6.102uM, shows a moderate inhibitory effect on LPS-stimulated production of TNF-α with an IC 50 value of 20.102 uM, and exhibits moderate inhibition against butyrylcholinesterase.
CSN16369 Imperatorin 482-44-0 Imperatorin is a naturally occuring multiple-target inhibitor of NOS with IC50 value of 9.2 μM, BChE with IC50 value of 31.4 μM, a potent calcium antagonist on vascular smooth muscle. It is also a weak agonist of TRPV1 with EC50 of 12.6±3.2 μM.
CSN19291 (5R,9R,E)-5-Amino-11-ethylidene-7-methyl-5,6,9,10-tetrahydro-5,9-methanocycloocta[b]pyridin-2(1H)-one 102518-79-6 Huperzine A is a naturally occurring sesquiterpene alkaloid AChE inhibitor.
CSN11139 Hederacoside C 14216-03-6 Hederacoside C is a naturally occuring saponin found in K. pictus with anti-inflammatory activity. It inhibited AChE with IC50 value of 31.3 μM.
CSN14086 Garcinone C 76996-27-5 Garcinone C, a natural product isolated and purified from the fruits of Garcinia mangostana, is the most potent inhibitor of AChE, the most active compound against both of pathogenic (MIC =100 μg/mL) and non-pathogenic leptospira (MIC = 200 μg/mL), and exhibits either significant or moderate cytotoxicity against MCF-7, A549, Hep-G2 and CNEhuman cancer cell lines in vitro.
CSN19397 (4aS,6R,8aS)-3-Methoxy-11-methyl-5,6,9,10,11,12-hexahydro-4aH-benzo[2,3]benzofuro[4,3-cd]azepin-6-ol 357-70-0 Galanthamine is a long-acting, centrally active acetylcholinesterase (AChE) inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors.
CSN19398 Galanthamine HBr 1953-04-4 Galanthamine hydrobromide is a natural occuring AchE inhibitor with IC50 value of 410nM and allosteric potentiator at neuronal nAchRs, used for the treatment of cognitive decline in mild to moderate Alzheimer's disease and various other memory impairments.
CSN12443 Galanthaminone 510-77-0 Galantamine is a competitive and reversible cholinesterase (AChE) inhibitor and is used for the treatment of mild to moderate Alzheimer's disease and various other memory impairments.
CSN13455 5-Methoxy-9-methyl-2,3,3a,3a1,8,9,10,11-octahydro-4-oxa-9-azacycloocta[def]fluoren-2-ol hydrobromide 69353-21-5 Galantamine hydrobromid is used for treatment of mild to moderate dementia of the Alzheimer type. It is a selective, reversible, competitive, alkaloid AChE inhibitor, with an IC50 value of 0.35µM.
CSN10888 N-Ethyl-3-hydroxy-N,N-dimethylbenzenaminium chloride 116-38-1 Edrophonium chloride is a competitive AchE inhibitor which can prevent breakdown of the neurotransmitter acetylcholine.
CSN16651 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one 120014-06-4 Donepezil is a centrally acting reversible AchE inhibitor with IC50 of 8.12 nM and 11.6 nM for bAChE and hAChE, respectively, a medication used to treat Alzheimer's disease.
CSN21326 Dimetacrine 4757-55-5 Dimetacrine is a useful antidepressant which can be used for the treatment of various types of depression.
CSN23810 Demecarium Bromide 56-94-0 Demecarium Bromide (BC-48) is a potent cholinesterase inhibitor, with an apparent affinity (Kiapp) of 0.15 μM[1]. Demecarium Bromide (BC-48) is used as a glaucoma agent[2].
CSN27305 Coumaran 496-16-2 Coumaran (2,3-Dihydrobenzofuran) is an acetylcholinesterase (AChE) inhibitor isolated from leaves of L. camara. Coumaran can be used as a biopesticide.
CSN10698 Corydaline 518-69-4 Corydaline is an acetylcholinesterase inhibitor isolated from Corydalis yanhusuo.
CSN10483 Bretylium tosylate 61-75-6 Bretylium tosylate is an antiarrhythmic agent.
CSN14035 β-Amyrone 638-97-1 beta-Amyrone, a natural product isolated and purified from the leaves of Cyclocarya paliums with snakevenom inactivating action, exhibits moderate anti-acetylcholinesterase (AChE) activity.
CSN14397 α-Viniferin 62218-13-7 alpha-Viniferin, a natural product isolated and purified from the herb of Carex humilis Leyss., a specific, reversible and noncompetitive AChE inhibitor (IC50 = 2.0 mM), exhibits a dose-dependent inhibition on cyclooxygenase activity, where 50% of inhibition (IC50) was shown at a final concentration of about 7 mM, and has anti-inflammatory activity, down-regulating STAT-1-inducible inflammatory genes via inhibiting ERK-mediated STAT-1 activation in IFN-gamma-stimulated macrophages.
CSN10233 Aldicarb sulfone 1646-88-4 Aldicarb sulfone, a carbamate insecticide, is a cholinesterase inhibitor which prevents the breakdown of acetylcholine in the synapse.
CSN19809 Acotiamide 185106-16-5 Acotiamide is a drug approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. It acts as an acetylcholinesterase inhibitor.
CSN23387 Acotiamide HCl 185104-11-4 Acotiamide HCl is the 2HCl form of acotiamide which is an inhibitor of AChE. It also acts as a prokinetic drug through acetylcholinesterase inhibition and muscarinic receptor antagonism that is used for the treatment of functional dyspepsia.
CSN22581 Acotiamide HCl trihydrate 773092-05-0 Acotiamide HCl 3H2O is AchE inhibitor which can increased Ach concentrations and lead to an improvement of gastric emptying and gastrointestinal motility and eventually to a reduction of dyspepsia symptoms.
CSN19329 Isochlorogenic acid B 14534-61-3 3,4-Dicaffeoylquinic Acid is a polyphenol with diverse biological activities, it inhibits acetylcholinesterase (ACE) and α-glucosidase in a concentration-dependent manner, shows cytotoxic to NCI-H23 lung adenocarcinoma cells, as well as increases tumor necrosis factor-related apoptosis inducing ligand (TRAIL) mRNA, reduces influenza H1N1 hemagglutinin (HA) mRNA and increases survival in a mouse model of influenza A infection.
CSN24966 Naphthalen-1-yl acetate 830-81-9 1-Naphthyl acetate is usually used in a rapid staining method for identification of macrophages.
CSN16855 (±)-Huperzine A 120786-18-7 (±)-Huperzine A is an active Lycopodium alkaloid extracted from traditional Chinese herbs of Lycopodium serratum, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimer's disease (AD).
CSN10699 Corynoline 18797-79-0 (+)-Corynoline is an AChE inhibitor isolated from Corydalis incisa.
<< PREV 1 2 3 4 NEXT >>
dandb BBB norton fedex dhl ups 顺丰

csnpharm版权所有2023，产品仅用于科研！

联系
我们