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Ack1
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN18846 | XMD8-87 | 1234480-46-6 | XMD8-87 is a tyrosine kinase nonreceptor 2 (TNK2) inhibitor with IC50s of 38 nmol/L and 113 nmol/L for the D163E and R806Q mutations. |
| CSN18847 | XMD16-5 | 1345098-78-3 | XMD16-5 is an inhibitor of TNK2 with IC50 value of 0.38µM, potently inhibiting phosphorylation of TNK2 truncation mutations found in solid tumor types. |
| CSN16660 | AIM-100 | 873305-35-2 | AIM-100 is a potent and selective Ack1 (TNK2) inhibitor with IC50 value of 22nM, showing suppression phosphorylation of Tyr267 of the androgen receptor in prostate cancer cells. |