Activated CDC42 Kinase 1 | Protein Tyrosine Kinase/RTK| CSNpharm

Ack1

Ack1
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货号	产品名	CAS号	信息
CSN18846	XMD8-87	1234480-46-6	XMD8-87 is a tyrosine kinase nonreceptor 2 (TNK2) inhibitor with IC50s of 38 nmol/L and 113 nmol/L for the D163E and R806Q mutations.
CSN18847	XMD16-5	1345098-78-3	XMD16-5 is an inhibitor of TNK2 with IC50 value of 0.38µM, potently inhibiting phosphorylation of TNK2 truncation mutations found in solid tumor types.
CSN26520	Mps1-IN-1 dihydrochloride	1883548-93-3	Mps1-IN-1 dihydrochloride is a potent, selective and ATP-competitive Mps1 kinase inhibitor, with an IC50 and a Kd of 367 nM and 27 nM[1].
CSN17890	KRCA-0008	1472795-20-2	KRCA-0008 is a potent and selective ALK/Ack1 inhibitor with IC50 of 12 nM/4 nM for ALK and Ack1 respectively and displays drug-like properties without hERG liability.
CSN16660	AIM-100	873305-35-2	AIM-100 is a potent and selective Ack1 (TNK2) inhibitor with IC50 value of 22nM, showing suppression phosphorylation of Tyr267 of the androgen receptor in prostate cancer cells.