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ADC Linker with Payload
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN20152 | Vat-Cit-PAB-Monomethyl Dolastatin 10 | 1415329-13-3 | Vat-Cit-PAB-Monomethyl Dolastatin 10 is an antibody drug conjugate cytotoxin. |
| CSN18875 | Val-Cit-PAB-MMAE | 644981-35-1 | Val-Cit-PAB-MMAE is a potent tubulin inhibitor (MMAE), Val-Cit-PAB-MMAE is an antibody drug conjugate. |
| CSN26872 | MC-VC-PAB-Tubulysin M | 1639939-56-2 | MC-vc-PAB-Tubulysin M consists a cleavable ADC linker (MC-vc-PAB) and a cytotoxic tubulin inhibitor Tubulysin M (HY-N7053). Tubulysin M is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis[1]. |
| CSN20151 | MC-Val-Ala-PBD | 1342820-51-2 | MC-Val-Ala-PBD is an antibody drug conjugate cytotoxin. |
| CSN26875 | MC-PBD | 1342820-52-3 | MC-PBD consists a non-cleavable ADC linker MC and a cytotoxic DNA crosslinking pyrrolobenzodiazepine (PBD). MC-PBD can be used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
| CSN20147 | DM4-SPDP | 2245698-48-8 | DM4-SPDP is an antibody drug conjugate cytotoxin. |
| CSN20154 | DM4-SMCC | 1228105-52-9 | DM4-SMCC is an antibody drug conjugate cytotoxin. |
| CSN20146 | DM1-SPP | 452072-20-7 | DM1-SPP is an antibody drug conjugate cytotoxin. |
| CSN20153 | DM1-SMCC | 1228105-51-8 | DM1-SMCC is an antibody drug conjugate cytotoxin. |
| CSN26873 | DBM-MMAF | 1810001-93-4 | DBM-MMAF is a drug-linker conjugate composed of a potent antitubulin agent MMAF and a linker DBM to make antibody drug conjugate (ADC)[1]. |
| CSN26871 | DBCO-PEG4-VC-PAB-MMAE | 2129164-91-4 | DBCO-PEG4-VC-PAB-MMAE consists a ADC linker (DBCO-PEG4-VC-PAB) and a tubulin polymerization inhibitor MMAE (HY-15162). DBCO-PEG4-VC-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs). MMAE is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization[1]. |
| CSN26868 | DBCO-PEG4-Val-Cit-PAB-MMAF | 2244602-23-9 | DBCO-PEG4-Val-Cit-PAB-MMAF consists a cleavable 4 unit PEG ADC linker (DBCO-PEG4-Val-Cit-PAB) and a potent tubulin polymerization inhibitor (MMAF). DBCO-PEG4-Val-Cit-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
| CSN15788 | Ansamitocin P-3' | 66547-09-9 | Ansamitocin P 3' exhibits antitumour activity, is an antibody drug conjugate cytotoxin. |
| CSN26866 | AcLysValCit-PABC-DMAE-SW-163D | 2411007-69-5 | AcLysValCit-PABC-DMAE-SW-163D is a drug-linker conjugates for ADC which consists of a natural bis-intercalator, SW-163D, conjugated via an AcLysValCitPABC-DMAE linker[1]. |
