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ADC Linker with Payload

ADC Linker with Payload

货号 产品名 CAS号 信息
CSN20152 Vat-Cit-PAB-Monomethyl Dolastatin 10 1415329-13-3 Vat-Cit-PAB-Monomethyl Dolastatin 10 is an antibody drug conjugate cytotoxin.
CSN18875 Val-Cit-PAB-MMAE 644981-35-1 Val-Cit-PAB-MMAE is a potent tubulin inhibitor (MMAE), Val-Cit-PAB-MMAE is an antibody drug conjugate.
CSN26872 MC-VC-PAB-Tubulysin M 1639939-56-2 MC-vc-PAB-Tubulysin M consists a cleavable ADC linker (MC-vc-PAB) and a cytotoxic tubulin inhibitor Tubulysin M (HY-N7053). Tubulysin M is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis[1].
CSN20151 MC-Val-Ala-PBD 1342820-51-2 MC-Val-Ala-PBD is an antibody drug conjugate cytotoxin.
CSN26875 MC-PBD 1342820-52-3 MC-PBD consists a non-cleavable ADC linker MC and a cytotoxic DNA crosslinking pyrrolobenzodiazepine (PBD). MC-PBD can be used in the synthesis of antibody-drug conjugates (ADCs)[1].
CSN20147 DM4-SPDP 2245698-48-8 DM4-SPDP is an antibody drug conjugate cytotoxin.
CSN20154 DM4-SMCC 1228105-52-9 DM4-SMCC is an antibody drug conjugate cytotoxin.
CSN20146 DM1-SPP 452072-20-7 DM1-SPP is an antibody drug conjugate cytotoxin.
CSN20153 DM1-SMCC 1228105-51-8 DM1-SMCC is an antibody drug conjugate cytotoxin.
CSN26873 DBM-MMAF 1810001-93-4 DBM-MMAF is a drug-linker conjugate composed of a potent antitubulin agent MMAF and a linker DBM to make antibody drug conjugate (ADC)[1].
CSN26871 DBCO-PEG4-VC-PAB-MMAE 2129164-91-4 DBCO-PEG4-VC-PAB-MMAE consists a ADC linker (DBCO-PEG4-VC-PAB) and a tubulin polymerization inhibitor MMAE (HY-15162). DBCO-PEG4-VC-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs). MMAE is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization[1].
CSN26868 DBCO-PEG4-Val-Cit-PAB-MMAF 2244602-23-9 DBCO-PEG4-Val-Cit-PAB-MMAF consists a cleavable 4 unit PEG ADC linker (DBCO-PEG4-Val-Cit-PAB) and a potent tubulin polymerization inhibitor (MMAF). DBCO-PEG4-Val-Cit-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs)[1].
CSN15788 Ansamitocin P-3' 66547-09-9 Ansamitocin P 3' exhibits antitumour activity, is an antibody drug conjugate cytotoxin.
CSN26866 AcLysValCit-PABC-DMAE-SW-163D 2411007-69-5 AcLysValCit-PABC-DMAE-SW-163D is a drug-linker conjugates for ADC which consists of a natural bis-intercalator, SW-163D, conjugated via an AcLysValCitPABC-DMAE linker[1].
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