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ADC Linker
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN28769 | Mc-Phe-Lys(Boc)-PAB | 756487-18-0 | TKN8718 is a hydrolyzable ADC linker. |
| CSN26807 | Tetrazine-biotin | 1714123-51-9 | Tetrazine-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
| CSN27345 | Dihydrofuran-2,5-dione | 108-30-5 | Succinic anhydride is a cyclic anhydride and a nonclaevable ADC linker extracted from patent WO2009064913A1. Succinic anhydride can react with compound 4 of the patent to link the prodrug to an amine or hydroxy 1 group of a targeting polypeptide. |
| CSN27321 | N-Succinimidyl iodoacetate | 39028-27-8 | SIA Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| CSN27316 | Propargyl-PEG3-acid | 1347760-82-0 | Propargyl-PEG3-acid is a non-cleavable (3 unit PEG) ADC linker and also a PEG-based PROTAC linker that can be used to synthesis 6-OHDA-PEG3-yne. 6-OHDA-PEG3-yne contains 6-OHDA (HY-B1081, HY-B1081A) and Propargyl-PEG3-acid. |
| CSN27342 | Propargyl-PEG2-amine | 944561-44-8 | Propargyl-PEG2-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
| CSN27339 | PDEC-NB | 874302-76-8 | PDEC-NB is a disulfide cleavable linker used for the antibody-drug conjugate (ADC). |
| CSN27315 | NH2-PEG6-Boc | 1286281-32-0 | NH2-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. NH2-PEG6-Boc is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| CSN27328 | NH2-PEG4-CH2CH2COOH | 663921-15-1 | NH2-PEG4-CH2CH2COOH is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| CSN27338 | NH-bis(C1-Boc) | 85916-13-8 | NH-bis(C1-Boc)is a uncleavable linker used for antibody-drug conjugates (ADC). |
| CSN27344 | N-Hydroxysulfosuccinimide sodium salt | 106627-54-7 | N-Hydroxysulfosuccinimide (sodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| CSN27330 | (S)-N-(2-Oxotetrahydrofuran-3-yl)butyramide | 67605-85-0 | N-Butanoyl-L-homoserine lactone is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm. |
| CSN27318 | N-Boc-PEG3-bromide | 165963-71-3 | N-Boc-PEG3-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| CSN27317 | N-Boc-PEG2-bromide | 164332-88-1 | N-Boc-PEG2-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| CSN27343 | 2,5-Dioxopyrrolidin-1-yl 3-(2-(2-(3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido)ethoxy)ethoxy)propanoate | 955094-26-5 | Mal-amido-PEG2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. |
| CSN26805 | m-PEG6-SS-PEG6-methyl | 1007386-15-3 | m-PEG6-SS-PEG6-methyl is a cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
| CSN27329 | m-PEG3-CH2CH2COOH | 67319-28-2 | m-PEG3-CH2CH2COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| CSN27352 | m-PEG3-Amine | 74654-07-2 | m-PEG3-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| CSN27349 | m-PEG2-Amine | 31576-51-9 | m-PEG2-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| CSN27320 | m-PEG10-alcohol | 27425-92-9 | m-PEG10-alcohol (Decaethylene glycol monomethyl ether) is a non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG10-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
| CSN27341 | Hydroxy-PEG4-acid | 937188-59-5 | Hydroxy-PEG4-acid is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| CSN27325 | Hydroxy-PEG4-(CH2)2-Boc | 518044-32-1 | Hydroxy-PEG4-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG4-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 191). |
| CSN27348 | Hydroxy-PEG3-(CH2)2-Boc | 186020-66-6 | Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196). |
| CSN27346 | Hydroxy-PEG2-(CH2)2-Boc | 133803-81-3 | Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196). |
| CSN27335 | Hydroxy-PEG10-Boc | 778596-26-2 | Hydroxy-PEG10-Boc is extacted from patent CN108707228 (example 0024). Hydroxy-PEG10-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG10-Boc can be conjugated to Paclitaxel (HY-B0015) or docetaxel (HY-B0011). |
| CSN26808 | Gly-Gly-Gly-PEG4-DBCO | 2353409-80-8 | Gly-Gly-Gly-PEG4-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
| CSN26806 | Gly-Gly-Gly-PEG3-TCO | 2353409-81-9 | Gly-Gly-Gly-PEG3-TCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
| CSN28768 | Fmoc-Phe-Lys(Boc)-PAB | 206133-42-8 | Fmoc-Phe-Lys(Boc)-PAB is a hydrolyzable ADC linker. |
| CSN27333 | Fmoc-NH-PEG8-CH2CH2COOH | 756526-02-0 | Fmoc-NH-PEG8-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| CSN27323 | Fmoc-NH-PEG6-CH2COOH | 437655-96-4 | Fmoc-NH-PEG6-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| CSN27327 | Fmoc-NH-PEG5-CH2COOH | 635287-26-2 | Fmoc-NH-PEG5-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| CSN27322 | 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azaoctadecan-18-oic acid | 437655-95-3 | Fmoc-NH-PEG4-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| CSN27326 | Fmoc-NH-PEG4-CH2CH2COOH | 557756-85-1 | Fmoc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| CSN27353 | Fmoc-NH-PEG3-CH2CH2COOH | 867062-95-1 | Fmoc-NH-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| CSN27355 | Fmoc-NH-PEG2-CH2CH2COOH | 872679-70-4 | Fmoc-NH-PEG2-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| CSN27319 | Fmoc-NH-PEG1-CH2COOH | 260367-12-2 | Fmoc-NH-PEG1-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| CSN28435 | EC1167 | 1610414-00-0 | EC1167 is the linker for EC1169 which is a PSMA-targeted tubulysin B-containing conjugate. |
| CSN27351 | Di(N-succinimidyl)suberate | 68528-80-3 | DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| CSN27350 | Di(N-succinimidyl) 3,3-Dithiodipropionate [Cross-linking Reagent] | 57757-57-0 | DSP Crosslinker is a cleavable ADC linker, used in the synthesis of antibody-drug conjugates (ADCs). |
| CSN26803 | BS3 Crosslinker disodium | 127634-19-9 | BS3 Crosslinker disodium is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
| CSN27340 | Boc-NH-PEG6-CH2CH2COOH | 882847-13-4 | Boc-NH-PEG6-CH2CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC). |
| CSN27337 | Boc-NH-PEG4-CH2CH2NH2 | 811442-84-9 | Boc-NH-PEG4-CH2CH2NH2 a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| CSN27313 | t-Boc-N-amido-PEG1-acid | 1260092-44-1 | Boc-NH-PEG1-CH2CH2COOH is a cleavable (1 unit PEG) ADC linker and also a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of antibody-drug conjugates (ADCs) or PROTACs. |
| CSN27324 | Boc-NH-ethyl-SS-propionic acid | 485800-27-9 | Boc-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| CSN27347 | Boc-NH-C6-Br | 142356-33-0 | Boc-NH-C6-Br is a cleavable linker used for antibody-drug conjugates (ADC). |
| CSN27314 | Bis-PEG9-acid | 1268488-70-5 | Bis-PEG9-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG9-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| CSN26810 | Bis-(PEG6-acid)-SS | 2055014-97-4 | Bis-(PEG6-acid)-SS is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
| CSN27334 | Amino-PEG8-Boc | 756526-06-4 | Amino-PEG8-Boc is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| CSN27336 | Amino-PEG3-C2-acid | 784105-33-5 | Amino-PEG3-C2-acid is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
