400-920-2911 sales@csnpharm.cn
Adenosine Receptor
货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN24475 | Xanthine amine congener hydrochloride | 1783977-95-6 | XAC is an adenosine receptor antagonist with IC50 value of 16μM for Adenosine Receptor A2. |
CSN19829 | Trabodenoson | 871108-05-3 | Trabodenoson is a potent and highly selective adenosine A1 receptor agonist. |
CSN16416 | Theophylline | 58-55-9 | Theophylline is a natural product present in tea and cocoa, working as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. |
CSN21258 | Tecadenoson | 204512-90-3 | Tecadenoson is a selective A1 adenosine receptor agonist. |
CSN27356 | Taminadenant | 1337962-47-6 | Taminadenant is an antagonist of adenosine receptor. |
CSN23108 | SCH442416 | 316173-57-6 | SCH-442416 is a selective adenosine A2A receptor antagonist. SCH-442416 binds to human and rat A2A receptors with high affinity (Ki values are 0.048 and 0.5 nM respectively). It displays > 23000-fold selectivity for hA2A over hA1 in vitro with minimal affinity for hA2B and hA3 receptors (IC50 > 10 μM). |
CSN23057 | PSB-603 | 1092351-10-4 | PSB 603 is a adenosine A2B receptor antagonist with Ki of 0.553 nM. |
CSN23056 | PSB36 | 524944-72-7 | PSB 36 is a potent and selective A1 adenosine receptor antagonist that displays binding affinity of 0.12 nM for rA1. |
CSN23054 | PSB-0788 | 1027513-54-7 | PSB 0788 is a potent and selective adenosine A2B receptor antagonist with IC50 of 3.64 nM at human A2B receptor. |
CSN21946 | Proxyphylline | 603-00-9 | Proxyphylline is a xanthine-derivatived antagonists of A1 and A2 adenosine receptors, which relaxe smooth muscles, particularly bronchial muscles. |
CSN23050 | PQ-69 | 910045-32-8 | PQ 69 is a potent and selective A1 receptor inverse agonist taht exhibits high binding affinity at A1 receptor with Kis of 0.07 and 0.96 nM for rat and human receptors respectively. |
CSN23113 | (2R,3R,4R,5R)-5-(6-(Cyclohexylamino)-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol | 130714-47-5 | Potent, selective A1 agonist |
CSN23153 | TC-G 1004 | 1061747-72-5 | Potent and selective A2A antagonist |
CSN20000 | Neladenoson dalanate | 1239309-58-0 | Neladenoson dalanate is a potent and selective adenosine A1 receptor agonist, and potentially useful for treatment of cardiovascular diseases. |
CSN21751 | 5'-N-Ethylcarboxamidoadenosine | 35920-39-9 | NECA, an analog of adenosine, is agonist of adenosine receptors with Kis of 1880, 6660, and 3.5 nM for A1, A2A, and A3, respectively. |
CSN22994 | N6-Cyclopentyladenosine | 41552-82-3 | N6-Cyclopentyladenosine is a potent and selective adenosine A1 receptor agonist with Ki of 2.3 nM for human A1 receptor. |
CSN25517 | N-(2-Hydroxyethyl)adenosine | 4338-48-1 | N-(2-Hydroxyethyl)adenosine has been studied as an anticonvulsant through the activation of adenosine A1 receptor (AA1R). It attenuates cell death induced by H2O2 through antioxidant action. |
CSN24570 | MRS1220 | 183721-15-5 | MRS1220 is a potent and highly selective antagonist at the human A3 adenosine receptor. Ki values are 0.65, 305, and 52 nM at hA3, rA1 and rA2A respectively. MRS1220 displays an IC50 > 1 μM for inhibition of binding to rat A3 receptors. |
CSN22990 | MRS5698 | 1377273-00-1 | MRS 5698 is a high affinity and selective A3 adenosine receptor agonist with Ki ~ 3 nM. |
CSN22989 | MRS-3777 hemioxalate | 1186195-57-2 | MRS 3777 Hemioxalate is a high affinity adenosine A3 receptor antagonist with Ki of 47 nM. |
CSN22988 | MRS 1754 | 264622-58-4 | MRS 1754 is a selective adenosine A2B receptor antagonist with Ki of 1.97 nM for hA2B. |
CSN22987 | MRS-1706 | 264622-53-9 | MRS 1706 is a potent and selective adenosine A2B receptor inverse agonist with Ki of 1.39 nM. |
CSN22873 | Rolofylline | 136199-02-5 | KW 3902 is a Selective adenosine A1 receptor antagonist with Ki of 0.19 nM. |
CSN22860 | ISAM-140 | 932191-62-3 | ISAM 140 is a high affinity A2B receptor antagonist with Ki of 3.49 nM. |
CSN23107 | SCH 202676 Hydrobromide | 265980-25-4 | Inhibitor of ligand binding to G-protein-coupled receptors |
CSN22848 | HEMADO | 403842-38-6 | HEMADO is a high affinity and selective adenosine A3 receptor agonist with Ki of 1.1 nM for human A3. |
CSN22792 | DPCPX | 102146-07-6 | DPCPX is a potent and selective A1 adenosine receptor antagonist, both in vitro and in vivo, with Ki of 3.9 nM for human A1. |
CSN23120 | Derenofylline | 251945-92-3 | Derenofylline (SLV 320) is a potent, selective and orally active adenosine A1 receptor antagonist, with Ki values of 1 nM, 200 nM and 398 nM for human A1, A3 and A2A receptors respectively. Derenofylline suppresses cardiac fibrosis and attenuates albuminuria without affecting blood pressure in rats[1]. |
CSN22838 | GS-6201 | 752222-83-6 | CVT-6883 is a selective antagonist of adenosine A2B receptors with Ki of 22 nM for human A2B. |
CSN21199 | Ciforadenant(CPI-444) | 1202402-40-1 | CPI-444 is an orally administered antagonist of the adenosine A2A receptor. Upon oral administration, CPI-444 binds to adenosine A2A receptors expressed on the surface of immune cells, including T-lymphocytes, natural killer (NK) cells, macrophages and dendritic cells (DCs). |
CSN24568 | CGS 15943 | 104615-18-1 | CGS 15943 is a potent adenosine receptor antagonist with Ki values of 3.5, 4.2, 16 and 51 nM for human A1, A2A, A2B and A3 receptors respectively. |
CSN23897 | BAY-545 | 1699717-32-2 | BAY-545 is a structure-optimizd adenosine receptor A2B antagonist with IC50 value of of 59 nM. |
CSN24164 | BAY-218 | 2162982-11-6 | BAY-218 is an AHR antagonist. |
CSN22708 | BAY 60-6583 | 910487-58-0 | BAY 60-6583 is a potent adenosine A2B receptor agonist with EC50 of 2.83 nM for murine A2B receptor. |
CSN27286 | BAY 2416964 | 2242464-44-2 | BAY 2416964 is an antagonist of aryl hydrocarbon receptor (AhR) with IC50 of 341 nM. |
CSN21201 | Imaradenant (AZD4635) | 1321514-06-0 | AZD4635 is an A2AR antagonist which can reverse adenosine mediated T cell suppression. |
CSN21468 | Alloxazine | 490-59-5 | Alloxazine is a selective antagonist of A2B adenosine receptor. |
CSN23524 | Adenosine | 58-61-7 | Adenosine is a nucleoside that is composed of adenine and d-ribose and plays many important biological roles in addition to being components of DNA and RNA. |
CSN21333 | Adenosine antagonist-1 | 431040-19-6 | Adenosine antagonist-1 is an adenosine A3 receptor (AA3R) antagonist. |
CSN25244 | Adenosine amine congener | 96760-69-9 | Adenosine amine congener hydrate is a potent aqueous-soluble A1 adenosine receptor agonist with Ki value of 0.85nM for binding against [3H]N6-cyclohexyladenosine in rat cerebral cortex membranes. |
CSN24753 | AB928 | 2239273-34-6 | AB928 is a dual A2aR/A2bR antagonist that inhibits A2aR and A2bR with an equilibrium binding constant of 1.4 and 2 nM, respectively. |
CSN18264 | A2AR-agonist-1 | 41552-95-8 | A2AR-agonist-1 is a potent A2AR and ENT1 agonist with Ki of 4.39 and 3.47 for A2AR and ENT1. |
CSN24565 | 8-Cyclopentyl-1,3-dimethylxanthine | 35873-49-5 | 8-Cyclopentyl-1,3-dimethylxanthine is a selective antagonist of adenosine A1 receptor with pKi of 7.5-8. |
CSN24575 | (E)-8-(3-Chlorostyryl)caffeine | 147700-11-6 | 8-(3-Chlorostyryl)caffeine is a selective adenosine A2A receptor antagonist (Ki = 54 nM at rat A2) and monoamine oxidase B (MAO-B) inhibitor (Ki = 100 nM). |
CSN22645 | (2R,3R,4S,5R)-2-(2-Chloro-6-(cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | 37739-05-2 | 2-Chloro-N6-cyclopentyladenosine is a potent and selective adenosine A1 receptor agonist with Ki of 0.8 nM for human A1. |
CSN22617 | (±)-5'-Chloro-5'-deoxy-ENBA | 103626-26-2 | (±)-5'-Chloro-5'-deoxy-ENBA is a highly selective adenosine A1 receptor agonist with Ki of 0.51 nM. |
CSN32734 | KI-7 | 1489263-00-4 | |
CSN106584 | 2-Butyl-9-methyl-8-(2H-1,2,3-triazol-2-yl)-9H-purin-6-amine | 496955-42-1 | |
CSN107412 | (2-Amino-4,5-dimethylthiophen-3-yl)(3-(trifluoromethyl)phenyl)methanone | 132861-87-1 | |
CSN51551 | 4-Nitrophenyl hydrogen phenylphosphonate | 57072-35-2 |