Adenosylhomocysteinase

Adenosylhomocysteinase
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货号	产品名	CAS号	信息
CSN25865	WWL70	947669-91-2	WWL 70 is an inhibitor of α/β-hydrolase domain 6 (ABHD6) with IC50 of 70 nM.
CSN13147	2-(4-Carbamimidoyl-2,3-dihydro-1H-inden-1-ylidene)hydrazine-1-carboximidamide	149400-88-4	Sardomozide is a second-generation polyamine synthesis inhibitor.
CSN21126	Sardomozide dihydrochloride	138794-73-7	Sardomozide 2HCl is an S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC50 of 5 nM.
CSN29538	Mitoguazone	459-86-9	Mitoguazone is a guanylhydrazone with potential antineoplastic activity. Mitoguazone competitively inhibits S-adenosyl-L-methionine decarboxylase (SAMD), an enzyme involved in the synthesis of polyamines, resulting in decreased proliferation of tumor cells, antimitochondrial effects, and p53-independent apoptosis. Polyamines, specifically spermine and spermidine, are essential for thymidine kinase production, DNA synthesis, and cell proliferation. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).
CSN25677	JZP-430	1672691-74-5	JZP 430 is an irreversible α/β-hydrolase domain 6 (ABHD6) inhibitor with IC50 value of 44 nM.
CSN22021	Adenosine dialdehyde	34240-05-6	Adenosine dialdehyde (AdOx), an indirect inhibitor that can be incorporated by cells.
CSN21115	3-Deazaadenosine	6736-58-9	3-Deazaadenosine is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 µM; has anti-inflammatory, anti-proliferative and anti-HIV activity.