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Adrenergic Receptor
货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN16167 | Yohimbine | 146-48-5 | Yohimbine, a natural product isolated and purified from the peel of Corynante yohimbe, is a potent and relatively nonselective alpha 2-adrenergic receptor (AR) antagonist, with IC50 of 0.6 μM. |
CSN16445 | Methyl (1R,2S,4aR,13bS,14aS)-2-hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylate hydrochloride | 65-19-0 | Yohimbine HCl is naturall occuring alpha-2 adrenergic antagonist derived from the bark of the African tree Pausinystalia johimbe, used as a veterinary drug to reverse sedation in dogs and deer. |
CSN18767 | Tolazoline HCl | 59-97-2 | Tolazoline HCl is a competitive non-selective α-adrenergic receptor antagonist, used as a a vasodilator directly acting on blood vessels and also increasing cardiac output. |
CSN19307 | Tetrahydrozoline HCl | 522-48-5 | Tetrahydrozoline HCl is an imidazole-derived alpha-adrenergic receptor agonist which can result vasoconstriction and decreased nasal and ophthalmic congestion. |
CSN16773 | Terazosin | 63590-64-7 | Terazosin is a selective alpha1-antagonist used for treatment of symptoms of benign prostatic hyperplasia (BPH). |
CSN16688 | Tamsulosin | 106133-20-4 | Tamsulosin is an α1 adrenergic receptor blocker used to treat symptomatic benign prostatic hyperplasia (BPH), chronic prostatitis, and to help with the passage of kidney stones. |
CSN18749 | Piribedil | 3605-01-4 | Piribedil is an antiparkinsonian agent and piperazine derivative which acts as a D2 and D3 receptor agonist. |
CSN18980 | Piperoxan HCl | 135-87-5 | Piperoxan HCl is an α2 adrenoceptor antagonist. |
CSN16735 | Nicergoline | 27848-84-6 | Nicergoline is a non-selective alpha-adrenergic receptor antagonist which can decrease vascular resistance and increase arterial blood flow in the brain, improving the utilization of oxygen and glucose by brain cells. |
CSN18661 | Naphazoline | 835-31-4 | Naphazoline is the common name for 2-(1-naphthylmethyl)-2-imidazoline HCl, it is a sympathomimetic agent with marked alpha adrenergic activity. |
CSN16498 | 4-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazole hydrochloride | 86347-15-1 | Medetomidine HCl is an α2 adrenergic agonist used as both a surgical anesthetic and analgesic. |
CSN18745 | Lofexidine HCl | 21498-08-8 | Lofexidine HCl is an α2A-adrenergic receptor agonist, commonly used to alleviate the physical symptoms of heroin and other types of opioid withdrawal. |
CSN17318 | L755507 | 159182-43-1 | L-755507 is characterized as a potent and selective β3 adrenergic receptor partial agonist with EC50 of 0.43 nM. It is also recently identified to enhance CRISPR-mediated homology-directed repair (HDR) efficiency in human induced pluripotent stem cells (iPSCs) and other cell types. |
CSN20251 | L748337 | 244192-94-7 | L-748337 is a competitive β3-adrenoceptor antagonist that displays selectivity over β1 and β2 receptors (Ki values are 4.0, 204 and 390 nM for β3-, β2- and β1-adrenoceptors respectively). Inhibits cAMP accumulation in response to isoproterenol (IC50 = 6 nM). Reduces iNOS expression, attenuates nitric oxide-induced cell proliferation and induces apoptosis in a melanoma cell line. |
CSN18526 | Methyldopa HCl | 884-39-9 | L-(-)-α-Methyldopa HCl is an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive drug used as a sympatholytic or antihypertensive. |
CSN19723 | 4-(1-Hydroxy-2-((1-phenoxypropan-2-yl)amino)propyl)phenol hydrochloride | 579-56-6 | Isoxsuprine is a modulator of β2 adrenoreceptor and has agonist or antagonist effects. |
CSN19742 | Idazoxan HCl | 79944-56-2 | Idazoxan is an alpha2-adrenoceptor antagonist potentially for the treatment of schizophrenia. |
CSN18407 | rel-(2R,3R)-3-(Isopropylamino)-1-((7-methyl-2,3-dihydro-1H-inden-4-yl)oxy)butan-2-ol hydrochloride | 72795-01-8 | ICI 118551 HCl is a selective and inverse β2 adrenergic receptor antagonist with Ki values of 1.2, 120 and 257nM for β2, β1 and β3 receptors, respectively. |
CSN18342 | HOKU-81 | 58020-43-2 | HOKU-81, a bronchodilator, is one of the metabolites of tulobuterol. |
CSN19298 | Fenspiride HCl | 5053-08-7 | Fenspiride HCl is an antagonist of α-adrenergic receptors and H1 histamine receptors and also inhibits phosphodiesterase 4 and phosphodiesterase 3 activities with logIC50 values of 4.16 and 3.44, respectively. |
CSN19404 | Detomidine | 76631-46-4 | Detomidine produce dose-dependent sedative and analgesic effects, is a nonnarcotic, synthetic α2-adrenergic agonist. |
CSN20033 | CL 316243 | 138908-40-4 | CL-316243 is a potent and highly selective β3-adrenoceptor agonist (EC50 = 3 nM) and > 10000-fold selective over β1 and β2 receptors. CL-316243 restores the expression of down-regulated fatty acid oxidation genes in type 2 diabetic mice. |
CSN19303 | Bopindolol | 62658-63-3 | Bopindolol is a beta blocker. It is an ester which acts as a prodrug for its active metabolite 4-(3-t-butylamino-2-hydroxypropoxy)-2-methylindole. |
CSN20183 | Batefenterol | 743461-65-6 | Batefenterol is a Muscarinic antagonist and β2-Agonist possessing both muscarinic antagonist (MA) and β2-adrenoceptor agonist (BA) properties (MABA). |
CSN17267 | Atipamezole HCl | 104075-48-1 | Atipamezole HCl is a competitive α2-adrenergic receptor antagonist, mainly used in veterinary medicine. |
CSN18702 | Apraclonidine HCl | 73218-79-8 | Apraclonidine HCl is a clonidine-derived selective agonist of alpha2-adrenergic receptor. |
CSN17099 | N'-(2,4-Dimethylphenyl)-N-(((2,4-dimethylphenyl)imino)methyl)-N-methylformimidamide | 33089-61-1 | Amitraz is a broad spectrum insecticide and acaricide which works as an α2 adrenergic agonist. |
CSN21296 | AGN 192836 | 171102-29-7 | AGN 192836 is a potent and selective α2 adrenergic agonist with EC50s of 8.7, 41 and 6.6 nM for α2A, α2B and α2C receptor, respectively. |