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ALDH
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN24614 | Win 18446 | 1477-57-2 | WIN 18446 is an inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2) with IC50 of 0.3 μM. |
| CSN15746 | NCT-501 | 1802088-50-1 | NCT-501 is a potent and selective theophylline-based inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1), inhibits hALDH1A1 with IC50 of 40 nM, typically shows better selectivity over other ALDH isozymes and other dehydrogenases (hALDH1B1, hALDH3A1, and hALDH2, IC50 > 57 μM). |
| CSN10460 | Disulfiram | 97-77-8 | Disulfiram is a specific inhibitor of aldehyde-dehydrogenase (ALDH1), used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram acts as an allosteric inhibitor of MERS-CoV PLpro but as a competitive (or mixed) inhibitor of SARS-CoV PLpro. |
| CSN16397 | Daidzin | 552-66-9 | Daidzin can inhibit mitochondrial aldehyde dehydrogenase2 with IC50 of 80 nM and ALDH-I selectively (Ki=20 nM). Daidzin is purified from the root of Pueraria lobata with effective anti-atherosclerotic activities. |
| CSN22782 | CVT-10216 | 1005334-57-5 | CVT 10216 is a potent and selective aldehyde dehydrogenase-2 (ALDH2) inhibitor with IC50s of 29 and 1300 nM for ALDH2 and ALDH1, respectively. |
| CSN25276 | CM10 | 692269-09-3 | CM10 is an ALDH1A inhibitor that depletes CD133+ cancer stem cells. |
| CSN18233 | Alda-1 | 349438-38-6 | Alda-1 is an ALDH2 agonist, cell-permeable activator of both the wild-type ALDH2*1 and the asian E487K mutant ALDH2*2 forms of mitochondrial aldehyde dehydrogenase 2 (mtALDH2). |
| CSN23590 | 3,4-Dihydroxybenzeneacetic acid | 102-32-9 | 3,4-Dihydroxyphenylacetic Acid is a metabolite of dopamine, it can modulate the aldehyde dehydrogenase (ALDH) activity and protects the cells from the acetaldehyde-induced cytotoxicity in vitro. |
| CSN22659 | CM037 | 896795-60-1 |
