优势价格
快速发货
品质保证
技术支持
400-920-2911 sales@csnpharm.cn
Aldose Reductase
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN36334 | Zopolrestat | 110703-94-1 | Zopolrestat is a aldose reductase inhibitor. |
| CSN12110 | Tolrestat | 82964-04-3 | Tolrestat is a potent, orally active aldose reductase inhibitor with IC50 value of 35 nM. |
| CSN27705 | Ponalrestat | 72702-95-5 | Statil is a selective and noncompetitive aldose reductase 2 inhibitor with Ki value of 7.7nM. |
| CSN17888 | Ranirestat | 147254-64-6 | Ranirestat is an aldose reductase inhibitor being developed for the treatment of diabetic neuropathy. |
| CSN16506 | Isoliquiritigenin | 961-29-5 | Isoliquiritigenin is a licorice chalconoid, a type of natural phenols, and a sirtuin-activating compound. |
| CSN21685 | Imirestat | 89391-50-4 | Imirestat is an inhibitor of aldose reductase which is used for the treatment of diabetes. |
| CSN22130 | Fidarestat | 136087-85-9 | Fidarestat is an inhibitor of aldose reductase, with IC50s of 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10 and V301L AKR1B10, respectively; Fidarestat has the potential to treat diabetic disease. |
| CSN12976 | Epalrestat | 82159-09-9 | Epalrestat is an aldose reductase inhibitor with IC50 of 72 nM, and used for the treatment of diabetic neuropathy. |
| CSN14844 | Dehydroglyasperin D | 517885-72-2 | Dehydroglyasperin D, a natural product isolated and purified from the roots of Glycyrrhiza uralensis with anti-obesity, antioxidant, anti-aldose reductase, anticancer, anti-inflammator and strong ferric reducing activities, inhibits the proliferation of HT-29 human colorectal cancer cells through direct interaction with phosphatidylinositol 3-kinase, mediates suppression of both COX-2 expression and the MLK3 signalling pathway through direct binding and inhibition of MLK3, effectively scavenges DPPH, ABTS(+), and singlet oxygen radicals. |
| CSN25218 | AT-007 | 2170729-29-8 | AT-007 is a central nervous system (CNS) penetrant Aldose Reductase inhibitor (ARI) in Phase 1/2 development for treatment of Galactosemia. |
| CSN18314 | Alrestatin sodium | 51876-97-2 | Alrestatin sodium is an inhibitor of aldose reductase, an enzyme involved in the pathogenesis of complications of diabetes mellitus, including diabetic neuropathy. |
| CSN10270 | Alrestatin | 51411-04-2 | Alrestatin is an inhibitor of aldose reductase, an enzyme involved in the pathogenesis of complications of diabetes mellitus, including diabetic neuropathy. |
| CSN17745 | Caficrestat | 1355612-71-3 | Aldose reductase-IN-1 is an inhibitor of aldose reductase with IC50 of 28.9 pM. |
| CSN23670 | AKR1C1-IN-1 | 4906-68-7 | 3-bromo-5-phenyl Salicylic Acid is a cell-permeable salicylic acid compound that acts as a highly potent, active-site directed and substrate competitive AKR1C1 inhibitor (Ki = 4 nM) with moderate to excellent selectivity over AKR1C2, AKR1C3 and AKR1C4 (Ki = 0.087, 4.2 and 18.2 µM, respectively). |
