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ALK

ALK

货号 产品名 CAS号 信息
CSN22607 TP0427736 HCl 2459963-17-6 TP0427736 HCl is the HCl form of TP0427736 which is an inhibitor of ALK5 with IC50 of 2.72 nM and can reduce TGF-β induced growth.
CSN12422 NVP-TAE 684 761439-42-3 NVP-TAE684 is a potent and selective ALK inhibitor with IC50 of 3 nM in a cell-free assay, 100-fold more sensitive for ALK than InsR.
CSN16207 LDK378 2HCl 1380575-43-8 LDK378 2HCl is a selective ALK inhibitor with an IC50 of 0.2 nM, and also inhibits InsR, IGF-1R, STK22D, FLT3 and FGFR2 with IC50 values of 7 nM, 8 nM, 23 nM, 60 nM and 260 nM.
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