欢迎来到CSNpharm!产品仅用于科研!

400-920-2911 sales@csnpharm.cn

0

Alkaloids

Alkaloids

货号 产品名 CAS号 信息
CSN14756 Zanthobungeanine 64190-94-9 Zanthobungeanine, a natural product isolated and purified from the roots of Zanthoxylum nitidum with anti-inflammatory activity, shows the inhibitory action on the development of A549 cell only in high concentration and has no antipersonnel effect on A549 cell, moderate NO production inhibitory activity with an IC50 value of 37.26 mg /L, and obviously inhibitoryactivity to platelet aggregation caused by platelet-activating factor (PAF).
CSN12111 Tomatidine 77-59-8 Tomatidine, a natural product isolated and purified from the fruits of Lycopersicon esculentum Mill., shows antibiotic activity against small-colony variants of S. aureus, significantly suppresses the activity of ACAT and leads to reduction of atherogenesis. It also inhibits the phosphorylation of ERK, Akt, and the nuclear content of NF-κB.
CSN20944 Thermopsine 486-90-8 Thermopsine has antibacterial activity.
CSN11911 Securinine 5610-40-2 Securinine, a natural product isolated and purified from the leaves and twigs of Securinega suffruticosa with antifungal activity, induces apoptosis in human leukemia HL-60 cells, is a promising monocytic differentiation inducing agent for Acute Myeloid Leukemia (AML).
CSN15000 Sambutoxin 160047-56-3 Sambutoxin, a natural product isolated and purified from the rotted potato tubers, can cause toxic effects in rats, including body weight loss, feed refusal, hemorrhage in the stomach and intestines, and, finally, death when rats were fed diets supplemented with 0.05 and 0.1% sambutoxin.
CSN12999 Rocaglamide 84573-16-0 Rocaglamide, a naturally occurring product isolated from the herbs of Aglaia odorata Lour, induces apoptosis through the intrinsic death pathway in various human leukemia cell lines and in acute lymphoblastic leukemia, chronic myeloid leukemia and acute myeloid leukemia cells freshly isolated from patients.
CSN21015 Pingpeimine A 82841-67-6 Pingpeimine A is a kind of alkaloid compound.
CSN14002 Pellitorine 18836-52-7 Pellitorine, a natural product isolated and purified from the herbs of Anacyclus pyrethrum, shows cytotoxic, antiprotozoal and potent antiplatelet aggregation activities against HL60 and MCF-7 cell lines.
CSN11639 Oxysophoridine 54809-74-4 Oxysophoridine is a natural product isolated and purified from the herb of Sophora alopecuroidos L. Oxysophoridine inhibited N-methyl-D-aspartate NR1 mRNA and protein expression in the cerebral cortex of mice with cerebral ischemia/reperfusion injury.
CSN20963 Berlambine 549-21-3 Oxyberberine is isolated from the methanol extract of A. mexicana. It has been used to study the SW480 human colon cancer cell line.
CSN14542 Neoechinulin A 51551-29-2 Neoechinulin A, a natural product isolated and purified from Aspergillus chevalieri with anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-κB and p38 MAPK pathways, may block the phosphorylation of mitogen-activated protein kinase (MAPK) molecule p38, apoptosis signal-regulating kinase 1 (ASK-1) and nuclear translocation of nuclear factor-κB (NF-κB) p65 and p50 subunits, and ameliorate rotenone toxicity by activating a cytoprotective machinery that requires ATP and antioxidant/anti-nitration activities.
CSN21042 N-(3-Methoxybenzyl)palmitamide 847361-96-0 N-(3-Methoxybenzyl)palmitamide, found in lepidium meyenii walp., is a promising inhibitor of fatty acid amide hydrolase (FAAH). It could counteract the toxicity produced by Aβ (25-35).
CSN20991 Lycobetaine 2121-12-2 Lycobetaine, a phenanthridine alkaloid, is minor constituent from the amaryllidaceae family that has shown tumor inhibitory effects.
CSN25439 Isoliensinine 6817-41-0 Isoliensinine is a bisbenzylisoquinoline alkaloid extracted from the seed embryo of Nelumbo nucifera, with anti-oxidant and anti-inflammatory and anti-cancer activities. Isoliensinine induces apoptosis in triple-negative human breast cancer cells.
CSN20907 Isofebrifugine 32434-44-9 Isofebrifugine is isolated from the roots of dichroa febrifuga with antimalarial activity.
CSN14540 Gelsevirine 38990-03-3 Gelsevirine, a natural product isolated and purified from the herbs of Gelsemium elegans with anxiolytic activity, may be via the agonist action of glycine receptor in the brain, and can significantly inhibit the proliferation of human carcinoma cell line SW480 and MGC80-3 in a dose-dependent manner, the 50% inhibiting concentration(IC50)of gelsevirine on SW480 cells and MGC80-3 cells are 1.41±0.06 mM and 1.22±0.11 mM respectively.
CSN20957 Evolitrine 523-66-0 Evolitrine is one of the major alkaloids present in sri lankan acronychia pedunculata.
CSN23649 (±)-Evodiamine 518-18-3 Evodiamine, a naturally occurring indole alkaloid, is one of the main bioactive ingredients of Evodiae fructus. It shows effect on cancer, obesity, nociception, inflammation, cardiovascular diseases, Alzheimer's disease, infectious diseases and thermo-regulative effects.
CSN14581 Eriocalyxin B 84745-95-9 Eriocalyxin B, a natural product isolated and purified from the herbs of Isodon eriocalyx, is a potent NF-kappaB inhibitor, can inhibit the NF-kappaB transcriptional activity but not that of cAMP response element-binding protein.
CSN27544 Edpetiline 32685-93-1 Edpetiline is a principal alkaloid from P. eduardi. Edpetiline has significant antiinflammatory effects.
CSN19952 Dendrobine 2115-91-5 Dendrobine, a natural product isolated and purified from the herb of Dendrobium nobile Lindl., is an antagonist of β-alanine, taurine and of presynaptic inhibition in the frog spinal cord, has antitumor activity,can inhibit the growth of A549 cells through inducing apoptosis, which is partially dependent on mitochondrial-mediated pathway, and possesses antiviral activity against influenza A viruses, including A/FM-1/1/47 (H1N1), A/Puerto Rico/8/34 H274Y (H1N1), and A/Aichi/2/68 (H3N2) with IC50 values of 3.39 ± 0.32, 2.16 ± 0.91, 5.32 ± 1.68 ug/mL, respectively.
CSN15660 Daurisoline 70553-76-3 Daurisoline, a natural product isolated and purified from the roots of Menispermum dauricu with antiarrhythmic effects, exerts a blocking effect on hERG at concentrations below 30 uM, but does not affect the expression and function of the hERG channel.
CSN15660 Daurisoline 70553-76-3 Daurisoline, a natural product isolated and purified from the roots of Menispermum dauricu with antiarrhythmic effects, exerts a blocking effect on hERG at concentrations below 30 uM, but does not affect the expression and function of the hERG channel.
CSN10155 Coixol 532-91-2 Coixol is a natural product isolated and purifed from the seeds of Coix lacryma-jobi L.
CSN20855 6- Methoxydihydrosanguinarine 151890-26-5 6-Methoxydihydrosanguinarine is a benzophenanthridine alkaloid derived from the methanol extracts of Hylomecon hylomeconoides.
CSN14545 5-Hydroxy-4-Methoxycanthin-6-One 18110-86-6 5-Hydroxy-4-methoxycanthin-6-one, a natural product isolated and purified from the barks of Picrasma quassioides (D.Don) Benn with anti-inflammatory effect and protective effect on dextran sulfate sodium -induced rat colitis, exhibits significant cytotoxic activity against CNE2 cell line, reduces the development of carrageenan-induced paw edema and complete Freund's adjuvant (CFA)-induced chronic arthritis in rats.
CSN20871 9-Methoxycamptothecin 19685-10-0 10-Methoxycamptothecin is isolated from the barks of camptotheca acuminata decne which possesses high anti-cancer activity.
CSN14152 1-Hydroxyrutaecarpine 53600-24-1 1-Hydroxyrutaecarpine, a natural product isolated and purified from the fruits of Evodia rutaecarpa (Juss.) Benth., exhibits cytotoxicities (ED50 values < 4 mg/mL) against P-388 or HT-29 cell lines in vitro and antiplatelet activity induced by AA and shows an IC50 value of ca.1-2 mg/mL.
CSN20880 (R)-Coclaurine 2196-60-3 (R)-Coclaurine is a compound contained in the dried buds of magnolia salicifolia MAXIM. It showed negative inotropic effects.
CSN21028 (9Z)-N-[(3-Methoxyphenyl)methyl]-9-octadecenamide 883715-21-7 (9Z)-N-[(3-Methoxyphenyl)methyl]-9-octadecenamide has pharmaceutical property against exercise-induced fatigue via by modulating energy metabolism and improving antioxidant status.
CSN20987 (-)-Lotusine 6871-67-6 (-)-Lotusine is a new cyclopeptide alkaloid from zizyphus lotus with antihypertension and antibacterial activities.
CSN20929 (-)-Curine 436-05-5 (-)-Curine, an alkaloid isolated from chondrodendron platyphyllum, can inhibit viability of hepatocellular carcinoma cells in regardless of p53 status.
<< PREV 1 2 3 4 5 6 7 8 9 NEXT >>
联系
我们