400-920-2911 sales@csnpharm.cn
Alkaloids
货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN13605 | (S)-2-Amino-3-(carboxyformamido)propanoic acid | 5302-45-4 | β-ODAP is an analog of glutamic acid present in Lathyrus sativus (grass pea) that activates AMPA receptors. |
CSN12207 | 3-((4-Amino-2-methylpyrimidin-5-yl)methyl)-5-(2-hydroxyethyl)-4-methylthiazol-3-ium chloride | 59-43-8 | Vitamin B1 is a water-soluble vitamin, as are all vitamins of the B complex. |
CSN12204 | Vinpocetine | 42971-09-5 | Vinpocetine is a selective inhibitor for PDE1 with IC50 of 21 μM, it also blocks voltage-gated Na+ channels. It's a natural product isolated and purified from the herbs of Catharanthus roseus (L.) G. Don. |
CSN12193 | Vasicine | 6159-55-3 | Vasicine, a natural product isolated and purified from the leaves of Adhatoda vasica, is a potential cholinesterase inhibitor in development for treatment of Alzheimer's disease, and can regulate the inflammatory reaction. |
CSN12068 | Tetrahydroberberine,THB | 522-97-4 | Tetrahydroberberine is an isoquinoline alkaloid isolated and purified from the barks of Phellodendron chinense Schneid. It has micromolar affinity for dopamine D(2) (pK (i) = 6.08) and 5-HT(1A) (pK (i) = 5.38) receptors but moderate to no affinity for other relevant serotonin receptors(5-HT(1B), 5-HT(1D), 5-HT(3), and 5-HT(4); pK (i) < 5.00). |
CSN12067 | Tetrahydroalstonine | 6474-90-4 | Tetrahydroalstonine, a natural product isolated and purified from the herbs of Uncaria rhynchophylla (Miq.) Miq. ex Havil., preferentially blocks the pressor responses of post-synaptic alpha-adrenergic receptor activation due to exogenous and endogenouse noradrenaline, respectively. |
CSN23862 | Swainsonine | 72741-87-8 | Swainsonine is an inhibitor of α-mannosidase II which inhibits glycoprotein processing. |
CSN11976 | Stachydrine HCl | 4136-37-2 | Stachydrine HCl is a naturally occuring anti-metastatic agent in vitro which is isolated from seed husk and the pulp of the fruit of C. Leonurus. |
CSN11929 | (4bR,8aS,9S)-4-Hydroxy-3,7-dimethoxy-11-methyl-9,10-dihydro-5H-9,4b-(epiminoethano)phenanthren-6(8aH)-one hydrochloride | 6080-33-7 | Sinomenine Hydrocloride is a an alkaloid found in the root of the climbing plant Sinomenium acutum which has anti-inflammatory effects in several animal models of inflammation and inhibits mast cell degranulation and histamine release. It is used to treat inflammatory diseases like rheumatoid arthritis. |
CSN11892 | 13-Methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-c][1,3]dioxolo[4,5-i]phenanthridin-13-ium chloride | 5578-73-4 | Sanguinarine chloride is a naturally occuring benzophenanthridine alkaloid which can inhibit sodium/potassium-ATPase protein (Na+/K+ ATPase) and cause Epidemic dropsy. |
CSN11760 | (S)-N6-Propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine dihydrochloride | 104632-25-9 | Pramipexole 2HCl is an dopamine agonist and can inhibit multiple dopamine receptors including dopamine D2S receptor, dopamine D2L receptor, dopamine D3 receptor, and dopamine D4 receptor with respectively Ki values of 3.9, 2.2, 0.5 and 5.1 nM. |
CSN11731 | Piperlongumine | 20069-09-4 | Piperlongumine, a natural alkaloid from Piper longum L., increases the level of reactive oxygen species (ROS) and selectively kills cancer cells. It is a direct TrxR1 inhibitor with suppressive activity against gastric cancer and an inhibitor of CRM1 and is also an inhibitor of PI3K/Akt/mTOR in human breast cancer cells. |
CSN12413 | (2E,4E)-5-(Benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one | 94-62-2 | Piperine is a major alkaloid isolated from the P. longum fruits which possesses anti-inflammatory and antiarthritic effects. |
CSN11532 | Neferine | 2292-16-2 | Neferine, is a major alkaloid present in the green embryos of Nelumbo nucifera Gaertn with anti-arrhythmia, anti-hypertensive and vaso-relaxant properties , and is also a NF-κB inhibitor. |
CSN11485 | Myricetrin | 17912-87-7 | Myricitrin, a flavonoid compound isolated from the root bark of Myrica cerifera, which exerts antinociceptive effects. |
CSN11233 | Isotetrandrine | 477-57-6 | Isotetrandrine, a natural product isolated and purified from the roots of Stephania tetrandra S.Moore, dose-dependently suppresses the severity of LPS-induced ALI by inactivation of MAPK and NF-κB, which may involve the inhibition of tissue oxidative injury and pulmonary inflammatory process. |
CSN10697 | Gelsemine | 509-15-9 | Gelsemine a natural indole alkaloid isolated from flowering plants of the genus Gelsemium with potent activity as an agonist of the mammalian glycine receptor, showing effect on pathways/systems related to xenobiotic- or diet-induced oxidative stress, and in the treatment of anxiety and other conditions. |
CSN13548 | Evocarpine | 15266-38-3 | Evocarpine has an antimycobacterial activity on antagonistic effects of indoloquinazoline alkaloids. |
CSN13532 | Dihydroberberine | 483-15-8 | Dihydroberberine, a natural product isolated and purified from the tubers of Corydalis decumbens (Thunb.) Pers., has anti-tumor activity. Dihydroberberine improves in vivo efficacy in terms of counteracting increased adiposity, tissue triglyceride accumulation, and insulin resistance in high-fat-fed rodents, thus is potential therapeutic reagents for type 2 diabetes treatment. |
CSN12661 | Dehydroevodiamine | 67909-49-3 | Dehydroevodiamine is an alkaloid isolated from E. rutaecarpa and possesses anti-inflammatory, antiarrhythmic, hypotensive, and anti-amnesic biological activities. |
CSN10751 | Dauricine | 524-17-4 | Dauricine is a plant metabolite, chemically classified as a phenol, an aromatic ether, and an isoquinoline alkaloid. |
CSN10733 | Cytochalasin D | 22144-77-0 | Cytochalasin D, a metabolite of the fungus Drechslera dematoidea, which is about 10-fold more effective than cytochalasin B, inhibits CT26 tumor growth potentially through inhibition of cell proliferation, induction of cell apoptosis and suppression of tumor angiogenesis. |
CSN10732 | Cytochalasin B | 14930-96-2 | Cytochalasin B, a metabolite of the fungus Drechslera dematoidea, is an cell-permeable inhibitor of actin polymerization which inhibits cell division, migration and glucose transport and causes G2/M cell cycle arrest and apoptosis in HCT-116 colorectal carcinoma cells. |
CSN13519 | Corynoxeine | 630-94-4 | Corynoxeine is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation, and is a useful and prospective compound in the prevention and treatment for vascular diseases. |
CSN10698 | Corydaline | 518-69-4 | Corydaline is an acetylcholinesterase inhibitor isolated from Corydalis yanhusuo. |
CSN10506 | Bulleyaconitine A | 107668-79-1 | Bulleyaconitine A is an alkaloid with analgesic and anti-inflammatory activities. It is found in Aconitum bulleyanum and used for the treatment of chronic pain and rheumatoid arthritis. |
CSN10330 | Arecaidine | 499-04-7 | Arecaidine but-2-ynyl ester tosylate is a potent muscarinic agonist that shows 4.6-fold that is selectivity for mAChR M2 in the atrium versus those in the ileum. |
CSN10246 | Allantoin | 97-59-6 | Allantoin is a diureide of glyoxylic acid used as a skin conditioning agent. |
CSN10068 | Ajmaline | 4360-12-7 | Ajmaline, a natural alkaloid isolated and purified from the roots of Rauvolfia verticillata, is a class Ia antiarrhythmic agent. |
CSN10208 | 2-Acetoxy-N,N,N-trimethylethanaminium chloride | 60-31-1 | Acetylcholine chloride is a neurotransmitter that can induce the opening of calcium channels. |
CSN13080 | 9-Aminocamptothecin | 91421-43-1 | 9-Aminocamptothecin, a natural product isolated and purified from the barks of Camptotheca acuminata Decne, is an active derivative of camptothecin, which belongs to the general group of chemotherapy drugs called topoisomerase inhibitors. 9-Aminocamptothecin is an inhibitor of Topo I. |
CSN10176 | 7-Ethylcamptothecin | 78287-27-1 | 7-Ethylcamptothecin is derived from Camptothecin with anti-cancer activity against various murine tumors through inhibition of Topo I (topoisomerase). |
CSN13176 | (-)-Isocorypalmine | 483-34-1 | (-)-Isocorypalmine, a natural product isolated and purified from the tubers of Corydalis yanhusuo W. T. Wang, with significant antifungal activity, also acts as a D1 partial agonist and a D2 antagonist to produce its in vivo effects and may be a promising agent for treatment of cocaine addiction. |
CSN52428 | (4bR,8aS,9S)-4-Hydroxy-3,7-dimethoxy-11-methyl-9,10-dihydro-5H-9,4b-(epiminoethano)phenanthren-6(8aH)-one hydrochloride | 6080-33-7 | |
CSN98265 | N-Methyl-3-phenylpropan-1-amine | 23580-89-4 |