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AMPAR
货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN21669 | gamma-DGG | 6729-55-1 | γDGG is a blocker of AMPA receptor. |
CSN17953 | Fanapanel | 161605-73-8 | ZK200775 is a highly selective AMPA/kainate antagonist with little activity against NMDA with Ki values of 3.2 nM, 100 nM, and 8.5 μM against quisqualate, kainate, and NMDA, respectively. |
CSN17630 | Fanapanel hydrate | 1255517-78-2 | ZK200775 is a highly selective AMPA/kainate antagonist with little activity against NMDA and has Ki values of 3.2 nM, 100 nM, and 8.5 μM against quisqualate, kainate, and NMDA, respectively. |
CSN23205 | YM90K | 154164-30-4 | YM90K hydrochloride is an AMPA receptor antagonist. |
CSN22000 | Zonampanel | 210245-80-0 | YM 872 is an AMPA receptor antagonists and acts as antiepileptic drugs. |
CSN23175 | UBP-282 | 544697-47-4 | UBP-282 is an α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) and kainate receptor antagonist. |
CSN24615 | UBP310 | 902464-46-4 | UBP 310 is an antagonist of GluK1 (formerly GLUK5) kainate receptor with IC50 of 130 nM. |
CSN24617 | UBP 302 | 745055-91-8 | UBP 302 is a potent and selective GluK1 (formally GluR5)-subunit containing kainate receptor antagonist with KD of 402 nM. |
CSN24618 | U-54494ahydrochloride | 112465-94-8 | U-54494A hydrochloride is a selective non-competitive AMPA receptor antagonist with IC50 of 10-20 mM. |
CSN17301 | SYM2206 | 173952-44-8 | SYM2206 is a potent, non-competitive AMPA receptor antagonist (IC50= 2.8 μM). |
CSN13864 | Sunifiram | 314728-85-3 | Sunifiram is a piperazine derived ampakine-like drug(acting via AMPA receptors) which has nootropic effects in animal studies with significantly higher potency than piracetam. |
CSN20167 | Selurampanel | 912574-69-7 | Selurampanel is a competitive AMPA/kainate receptor antagonist drug for epilepsy. |
CSN24155 | Philanthotoxin 74 dihydrochloride | 1227301-51-0 | Philanthotoxin 74 dihydrochloride (PhTx 74) is an AMPAR antagonist; inhibits GluR3 and GluR1 with IC50s of 263 and 296 nM, respectively. |
CSN22487 | PF-4778574 | 1219633-99-4 | PF-4778574 is a positive allosteric modulation of AMPA receptor with EC50 of 45 to 919 nM in differenct cells. |
CSN32485 | Pesampator | 1258963-59-5 | PF-04958242 is an AMPA receptor positive allosteric modulator. |
CSN17813 | PEPA | 141286-78-4 | PEPA is an allosteric modulator of AMPA receptors and binds to the GluA2o and GluA3o LBDs and can be utilized as an indicator of AMPA receptor heterogeneity. |
CSN23006 | NPEC-caged-(S)-AMPA | 1257323-84-4 | NPEC-caged-(S)-AMPA is an agonist at the AMPA receptor. |
CSN22241 | NBQX | 118876-58-7 | NBQX is a potent, selective and competitive AMPAR antagonist, which shows activity of neuroprotective and anticonvulsant. |
CSN22999 | NBQX disodium | 479347-86-9 | NBQX Disodium Salt is a potent, selective and competitive AMPA receptor antagonist. |
CSN17585 | Naspm | 122306-11-0 | Naspm is a potent and selective Ca2+ permeable AMPA receptor (Ca-perm AMPAR) blocker. |
CSN17275 | Naspm trihydrochloride | 1049731-36-3 | Naspm 3HCl is a potent and selective Ca2+ permeable AMPA receptor (Ca-perm AMPAR) blocker. |
CSN20510 | LY3130481 | 1610802-47-5 | LY3130481 is the the first α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist that is dependent on the presence of TARP γ-8. LY3130481 is fully protective against pentylenetetrazole-induced convulsions in rats without the motor impairment associated with non-TARP-dependent AMPA receptor antagonists. |
CSN22957 | LY-404187 | 211311-95-4 | LY 404187 is a selective positive allosteric modulator of AMPA receptors with IC50s of 0.15, 0.21, 1.66 and 5.65 μM for GluA2i, GluA4i, GluA3i and GluA1i respectively. |
CSN11282 | Lentinan | 37339-90-5 | Lentinan, a natural product isolated and purified from shiitake mushroom (Lentinus edodes), is an intravenous anti-tumor polysaccharide isolated from the fruit body of shiitake. |
CSN16600 | L-Theanine | 3081-61-6 | L-theanine is an amino acid found most commonly in tea leaves and binds to ionotropic glutamate receptors in the micromolar range, including the AMPA and kainate receptors and, to a lesser extent, the NMDA receptor. |
CSN24076 | JNJ-61432059 | 2035814-50-5 | JNJ-61432059 is an oral active and selective negative modulator of AMPAR associated with trans-membrane AMPAR regulatory protein (TARP) γ-8, with a pIC50 of 9.7 for GluA1/γ-8. Exhibits time- and dose-dependent AMPAR/γ-8 receptor occupancy in mouse hippocampus, resulting in robust seizure protection in corneal kindling and pentylenetetrazole (PTZ) anticonvulsant models[1]. |
CSN22868 | JNJ-55511118 | 2036081-86-2 | JNJ 55511118 is a high affinity and selective negative modulator of AMPA receptors containing TARP-γ8 with Ki of 26 nM. |
CSN25362 | IDRA 21 | 22503-72-6 | IDRA-21 is a positive AMPA receptor modulator. IDRA-21 inhibits synaptic and extrasynaptic NMDA receptor mediated events in cultured cerebellar granule cells. IDRA 21 enhances ischemic hippocampal neuron injury. |
CSN21937 | GYKI 53655 hydrochloride | 143692-48-2 | GYKI53655 hydrochloride is an α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) antagonist. |
CSN22846 | GYKI 52466 | 102771-26-6 | GYKI 52466 2HCl is a selective non-competitive AMPA receptor antagonist with IC50 of 10-20 μM. |
CSN21401 | Quisqualic acid | 52809-07-1 | Glutamate receptor agonist acting at AMPA receptors and metabotropic glutamate receptors positively linked to phosphoinositide hydrolysis. Sensitizes neurons in hippocampus to depolarization by L-AP6 (the so called 'quis' effect). |
CSN27523 | Farampator | 211735-76-1 | Farampator (CX-691;Org24448) is an AMPA receptor positive modulator. |
CSN22784 | CX 614 | 191744-13-5 | CX 614 is a positive allosteric modulator of AMPA receptors. |
CSN19847 | CP 465022 free | 199655-36-2 | CP 465022 HCl is a selective, non-competitive AMPA receptor antagonist (IC50 = 25 nM in rat cortical neurons) that displays potent anticonvulsant activity. |
CSN22766 | CNQX | 115066-14-3 | CNQX is a potent and selective non-NMDA iGluR antagonist. |
CSN22767 | CNQX disodium | 479347-85-8 | CNQX Disodium Salt is a AMPA/kainate antagonist and also available as part of the Kainate Receptor. |
CSN17062 | CFM-2 | 178616-26-7 | CFM-2 is a selective non-competitive AMPAR antagonist. |
CSN22005 | Becampanel | 188696-80-2 | Becampanel (AMP397) is the first competitive AMPA antagonist and an antiepileptic agent. |
CSN24616 | ATPA | 140158-50-5 | ATPA is a selective and potent GluK1 kainate receptor agonist with Ki of 4.3 nM. |
CSN25263 | 1-BCP | 34023-62-6 | 1-BCP is can modulate AMPA receptor gated currents and enhence memory. |
CSN11876 | (S)-Willardiine | 21416-43-3 | (S)-Willardiine is a potent agonist of AMPA/kainate receptors with EC50 of 44.8 μM. |
CSN23429 | L-Glutamic acid | 56-86-0 | (S)-Glutamic acid acts as an excitatory neurotransmitter in the central nervous system. |
CSN22635 | (S)-AMPA | 83643-88-3 | (S)-AMPA is a selective AMPA agonist. |
CSN17690 | (S)-(-)-5-Fluorowillardiine hydrochloride | 1321546-70-6 | (S)-(-)-5-Fluorowillardiine HCl is a potent and specific AMPAR agonist. |
CSN19840 | 2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propanoic acid hydrobromide | 171259-81-7 | (RS)-AMPA hydrobromide is a class of glutamate agonist structurally related to ibotenic acid. |
CSN22625 | (R)-3,4-dcpg | 201730-10-1 | (R)-3,4-DCPG is a AMPA receptor antagonist. |
CSN22631 | (RS)-AMPA | 77521-29-0 | |
CSN51552 | Unifiram | 272786-64-8 |