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Amyloid-β
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN13757 | Tramiprosate | 3687-18-1 | Tramiprosate targets soluble Aβ to decrease amyloid plaque deposition and maintains Aβ in a non-fibrillar form. |
| CSN23629 | HP-β-CD | 128446-35-5 | HP-β-CD is used to improve the solubility of lipophilic drugs. It is also an inhibitor of amyloid-β aggregation and Aβ-induced toxicity. |
| CSN11056 | Frentizole | 26130-02-9 | Frentizole, an immunosuppressive drug, is an inhibitor of the Aβ-ABAD interaction. |
| CSN17194 | FPS-ZM1 | 945714-67-0 | FPS-ZM1 is a high-affinity RAGE-specific inhibitor that blocks Aβ binding to the V domain of RAGE with Ki of 25 ± 5 nM in RAGE-transfected CHO cells. |
| CSN11884 | EUK 134 | 81065-76-1 | EUK 134, a synthetic superoxide dismutase (SOD)/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril. |
| CSN27216 | Colivelin TFA | N/A | Colivelin TFA is a brain penetrant neuroprotective peptide and a potent activator of STAT3, suppresses neuronal death by activating STAT3 in vitro . Colivelin TFA exhibits long-term beneficial effects against neurotoxicity, Aβ deposition, neuronal apoptosis, and synaptic plasticity deficits in neurodegenerative disease . Colivelin TFA has the potential for the treatment of alzheimer's disease and ischemic brain injury . |
| CSN21167 | Aftin-4 | 866893-90-5 | Aftin-4 is a potent and selective Aβ42 inducer with an EC50 of 30 μM. |