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Amyloid-β

Amyloid-β

货号 产品名 CAS号 信息
CSN13757 Tramiprosate 3687-18-1 Tramiprosate targets soluble Aβ to decrease amyloid plaque deposition and maintains Aβ in a non-fibrillar form.
CSN23629 HP-β-CD 128446-35-5 HP-β-CD is used to improve the solubility of lipophilic drugs. It is also an inhibitor of amyloid-β aggregation and Aβ-induced toxicity.
CSN11056 Frentizole 26130-02-9 Frentizole, an immunosuppressive drug, is an inhibitor of the Aβ-ABAD interaction.
CSN17194 FPS-ZM1 945714-67-0 FPS-ZM1 is a high-affinity RAGE-specific inhibitor that blocks Aβ binding to the V domain of RAGE with Ki of 25 ± 5 nM in RAGE-transfected CHO cells.
CSN11884 EUK 134 81065-76-1 EUK 134, a synthetic superoxide dismutase (SOD)/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.
CSN27216 Colivelin TFA N/A Colivelin TFA is a brain penetrant neuroprotective peptide and a potent activator of STAT3, suppresses neuronal death by activating STAT3 in vitro . Colivelin TFA exhibits long-term beneficial effects against neurotoxicity, Aβ deposition, neuronal apoptosis, and synaptic plasticity deficits in neurodegenerative disease . Colivelin TFA has the potential for the treatment of alzheimer's disease and ischemic brain injury .
CSN21167 Aftin-4 866893-90-5 Aftin-4 is a potent and selective Aβ42 inducer with an EC50 of 30 μM.
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