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Antibacterial

Antibacterial

货号 产品名 CAS号 信息
CSN26514 Xinjiachalcone A 151410-32-1 Xinjiachalcone A is an active principle of Glycyrrhiza inflata Batalin. Xinjiachalcone A shows both a low MIC and a strong bactericidal activity against H. pylori, with MIC values ranged from 12.5 to 50 µM for seventeen H. pylori strains[1].
CSN21481 Amifloxacin 86393-37-5 Win49375, a synthetic quinolone compound, is antibacterial agent.
CSN24627 Viomycin 32988-50-4 Viomycin is a member of the tuberactinomycin family of antibiotics. It can inhibit group I intron splicing and prokaryotic protein synthesis.
CSN26391 Valinomycin 2001-95-8 Valinomycin, a cyclic depsipeptide antibiotic first isolated from Streptomyces fulvissimus, act as a potassium selective ionophore. Valinomycin inhibits lymphocyte proliferation by its effects on the cell membrane, and induces apoptosis in CHO cells[1]. Valinomycin induces activation of PINK1 leading to Parkin Ser65 phosphorylation[2].
CSN24708 Tyrphostin AG 30 122520-79-0 Tyrphostin AG 30 is an antimicrobial peptide with angiogenic properties. It activates human mast cells through the MAPK and NF-κB pathways.
CSN24630 Trovafloxacin Mesylate 147059-75-4 Trovafloxacin is a broad spectrum antibiotic that inhibits the uncoiling of supercoiled DNA in bacteria by blocking the activity of topoisomerase IV (IC50 = 3.02 µg/ml) and DNA gyrase (IC50 = 7.13 µg/ml).
CSN29488 Troleandomycin 2751-09-9 Troleandomycin is a macrolide antibiotic that is similar to Erythromycin.
CSN33126 Sulopenem 120788-07-0 Sulopenem is an orally active, parenteral penem antibiotic with broad-spectrum activities against Gram-positive and Gram-negative bacteria.
CSN21845 sulfaproxyline 116-42-7 Sulfaproxyline is a synthetic antimicrobial drug that is sulfonamide.
CSN22041 Sulfabrom 116-45-0 Sulfabrom is a long-acting veterinary medicine that is used for the treatment of coccidiosis and various bacterial infections in the poultry, swine and cattle.
CSN24116 Sodium benzoate 532-32-1 Sodium benzoate is a preservative and uesd as a food additive which is bacteriostatic and fungistatic under acidic conditions
CSN26531 Sandramycin 100940-65-6 Sandramycin ia a cyclic depsipeptide antibiotic isolated from cultured broth of a Nocardioides sp. Sandramycin is also a DNA intercalator that potently binds DNA and is an ADC cytotoxin. Sandramycin is active against Gram-positive bacteria and has potent antitumor activity[1][2][3].
CSN24749 Qstatin   902688-24-8 Qstatin is a potent and selective inhibitor of Vibrio quorum sensing (QS). SmcR is the LuxR homologue in V. vulnificus.
CSN28509 Protactin 141912-59-6 Protactin is a new antibiotic metabolite and a possible precursor of the actinomycins.
CSN33140 Plazomicin 1154757-24-0 Plazomicin is a next-generation aminoglycoside that has been designed as an antibiotic to avoid resistance through aminoglycoside-modifying enzymes. Plazomicin demonstrates high activity against the Enterobacteriaceae including extended spectrum beta lactamase and most carbapenemase producers, and can be useful in treating complicated urinary tract infections (cUTIs) and acute pyelonephritis.
CSN26585 Oxazosulfyl 1616678-32-0 Oxazosulfyl is a potent agricultural fungicide. Oxazosulfyl can be used as an insecticide against major rice pests[1].
CSN21752 Neomycin B 119-04-0 Neomycin B is an aminoglycoside antibiotic that can inhibit hammerhead ribozyme with a Ki of 13.5 μM.
CSN29541 Neamine 3947-65-7 Neamine is a non-toxic derivative derivative of Neomycin and is a broad-spectrum aminoglycoside antibiotic. Neamine is an anti-angiogenesis agent targeting angiogenin. Neamine has potent antibacterial, antitumor and neuroprotective activities.
CSN29540 Muramic acid 1114-41-6 Muramic acid is a component in many Gram-positive bacterial cell walls, as marker for Gram-positive bacteria.
CSN21737 Monobehenin 30233-64-8 Monobehenin can inhibit bacterial biofilm formation.
CSN21721 Magainin 1 108433-99-4 Magainin is a 23-residue peptide and naturally found on the skin of african clawed frog. It has a broad spectrum specificity towards many gram-negative bacteria.
CSN21722 Magainin 2 108433-95-0 Magainin II, an antibiotic in a variety of organisms, can bind to anionic phospholipids abundant in bacterial membranes and also exhibit cytotoxic.
CSN29492 Lincomycin 154-21-2 Lincomycin, also known as U-10149, is a lincosamide antibiotic that comes from the actinomycete Streptomyces lincolnensis. A related compound, clindamycin, is derived from lincomycin by using thionyl chloride to replace the 7-hydroxy group with a chlorine atom with inversion of chirality. Although similar in structure, antibacterial spectrum, and mechanism of action to macrolides, lincomycin is also effective against other organisms including actinomycetes and some species of Mycoplasma and Plasmodium. However, because of its adverse effects and toxicity, it is rarely used today and reserved for patients allergic to penicillin or where bacteria have developed resistance.
CSN24629 LF 11 832729-13-2 LF 11 is peptide based on the lipopolysaccharide (LPS)-binding region of human lactoferricin. It can neutralize LPS with antimicrobial activity against bacteria.
CSN24747 KKL-35 865285-29-6 KKL-35, a potent member of the oxadiazole family, against the human pathogen Legionella pneumophila and other related species that can also cause Legionnaires' disease.
CSN26437 Kasugamycin hydrochloride 19408-46-9 Kasugamycin hydrochloride is an antibiotic which binds both the 30S and 70S ribosome but not isolated 50S subunits. Kasugamycin hydrochloride mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation.
CSN21688 Indolicidin 140896-21-5 Indolicidin, a 13-residue cationic antimicrobial peptide-amide isolated from the cytoplasmic granules of bovine neutrophils. It is a member of the cathelicidin protein family.
CSN22002 H-Lys-Trp-Lys-OH 38579-27-0 H-Lys-Trp-Lys-OH is a small molecule peptide which displays antibacterial and antiviral activities extracted from patent CN 104072579 A, Compound AMP12.
CSN21660 Gramicidin 1405-97-6 Gramicidin is a polypeptide antibiotic mixture of gramicidin A, gramicidin B, and gramicidin C originally isolated from B. brevis.
CSN29513 2-(Phosphonooxy)benzoic acid 6064-83-1 Fosfosal, used as the anti-inflammatory agent, has the anti-bacterial effect.
CSN21645 Fibracillin 51154-48-4 Fibracillin is a penicillin antibiotic.
CSN18736 Epetraborole HCl 1234563-16-6 Epetraborole HCl is a leucyl-tRNA synthetase (LeuRS) inhibitor, which inhibits protein synthesis by binding "to the terminal adenosine ribose (A76) of leucyl-tRNA synthetase".
CSN22015 DuP 105 96800-41-8 DuP 105 is an orally active oxazolidinone, a new class of synthetic antimicrobial agent with activity against gram-positive bacteria.
CSN29485 Clinafloxacin (hydrochloride) 105956-99-8 Clinafloxacin is an antimicrobial antibiotic that displays broad-spectrum antibacterial activity against Gram-positive, Gram-negative, and anaerobic pathogens by inhibiting the bacterial regulatory enzyme DNA gyrase (IC50 = 0.92 µg/ml) as well as topoisomerase IV (IC50 = 1.62 µg/ml).
CSN26588 Ciprofloxacin HCl 93107-08-5 Ciprofloxacin hydrochloride is a broad-spectrum antimicrobial carboxyfluoroquinoline, an fluoroquinolone antibiotic that is widely used as an antimicrobial and immunomodulatory agent. It is capable of inducing respiratory, urinary tract, gastrointestinal, and abdominal infections. It functions by inhibiting DNA gyrase (a type II topoisomerase) and topoisomerase IV, the enzymes responsible for negative supercoiling of chromosomes and DNA strand separation, thus blocking initiation of bacterial replication. Most recently ciprofloxacin has been used in the management of postexposure inhalational anthrax and radiation combined injury resulting from nuclear disasters.
CSN29475 4-epi-Chlortetracycline (hydrochloride) 101342-45-4 Chlortetracycline is an analog of tetracycline. In addition to its actions against microorganisms, chlortetracycline suppresses inflammation by inhibiting neutrophil action and other aspects of the innate immune response.
CSN26433 Ceftazidime pentahydrate 78439-06-2 Ceftazidime pentahydrate is a third generation cephalosporin administered intravenously or intramuscularly. Ceftazidime pentahydrate has a broad spectrum of in vitro activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime pentahydrate is particularly active against Enterobacteriaceae (including beta-lactamase-positive strains) and is resistant to hydrolysis by most beta-lactamases[1].
CSN19177 Bismuth Subcitrate Potassium 880149-29-1 Bismuth subcitrate is an antibiotic used to treat stomach ulcers associated with Helicobacter pylori, a bacterial infection.
CSN21505 Bactenecin 116229-36-8 Bactenecin is a cyclic antimicrobial peptide isolated from bovine neutrophils with potent activity against bacterial and fungal species.
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