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AP-1 (activating protein-1) is a collective term referring to dimeric transcription factors composed of Jun, Fos or ATF (activating transcription factor) subunits that bind to a common DNA site, the AP-1-binding site.

AP-1

货号 产品名 CAS号 信息
CSN18329 PNRI-299 550368-41-7 PNRI-299 is a selective AP-1 transcription inhibitor with IC50 of 20 μM without affecting NF-kappaB transcription (up to 200 μM) or thioredoxin (up to 200 μM).
CSN20807 Ganoderenic acid B 100665-41-6 Ganoderic acid, a triterpene found in Ganoderma mushrooms, is reported to exhibit anti-tumor activity mediated through its inhibitory effect on NFKB and AP-1 as well as antimetastasis and anti-HIV activities.
CSN27551 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid 3719-45-7 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid is from Cordyceps bassiana, which is one of Cordyceps species with anti-oxidative, anti-cancer, anti-inflammatory, anti-diabetic, anti-obesity, anti-angiogenic, and anti-nociceptive activities. 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid targets to block AP-1-mediated luciferase activity, implying it has an anti-inflammatory function.
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