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Apoptosis Inducer
货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN21899 | Ubiquitin Isopeptidase Inhibitor I, G5 | 108477-18-5 | Ubiquitin Isopeptidase Inhibitor I, G5 is an apoptosome-independent caspase and apoptosis activator. |
CSN29557 | CLT-003 | 100823-03-8 | TC11 is a potent inhibitor of tumor cell proliferation and an inducer of apoptosis via activation of caspase-3, 8 and 9. |
CSN11500 | SMIP004 | 143360-00-3 | SMIP004 is an inducer of cancer-cell selective apoptosis of human prostate cancer cells, downregulates SKP2 and stabilizes p27. |
CSN13728 | Silvestrol | 697235-38-4 | Silvestrol is isolated from the fruits and twigs of Aglaia foveolata, by inducing caspase-3 activation to cause cell death. |
CSN18642 | Silvestrol Aglycone | 960365-65-5 | Silvestrol aglycone, an aglycone of potential anticancer rocaglate derivative from Aglaia foveolata, induces apoptosis in LNCaP cells through the mitochondrial/apoptosome pathway without activation of executioner caspase-3 or -7 and a 5'myc-UTR-LUC inhibtior (IC50= 0.8 nM). |
CSN11911 | Securinine | 5610-40-2 | Securinine, a natural product isolated and purified from the leaves and twigs of Securinega suffruticosa with antifungal activity, induces apoptosis in human leukemia HL-60 cells, is a promising monocytic differentiation inducing agent for Acute Myeloid Leukemia (AML). |
CSN26530 | Rabeprazole-d4 | 934295-48-4 | Rabeprazole D4 (LY307640 D4) is a deuterium labeled Rabeprazole. Rabeprazole is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole induces apoptosis. Rabeprazole acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an IC50 of 0.3 μM. Rabeprazole can be used for the research of gastric ulcerations and gastroesophageal reflux[1][2][3]. |
CSN17239 | NSC 348884 | 81624-55-7 | NSC348884 is a nucleophosmin (NPM) inhibitor, inhibits cell proliferation and induce apoptosis in various cancer cell lines with IC50 values ranging from 1.4-4 µM. |
CSN11375 | Meisoindigo | 97207-47-1 | Meisoindigo, a derivative of Indigo naturalis with anticancer activity, might induce apoptosis and myeloid differentiation of acute myeloid leukemia (AML). |
CSN23859 | Kinetin Riboside | 4338-47-0 | Kinetin riboside, a cytokinin analog, can induce apoptosis in cancer cells. It inhibits the proliferation of HCT-15 cells with an IC50 of 2.5 μM. |
CSN12309 | Isoalantolactone | 470-17-7 | Isoalantolactone is a naturally occuring sesquiterpene lactone isolated from Inula helenium with a role as an apoptosis inducer, an antifungal agent and a plant metabolite. |
CSN24957 | Geranyl acetate | 105-87-3 | Geranyl acetate is a natural organic compound that is used primarily as a component of perfumes for creams and soaps and as a flavoring ingredient. |
CSN26400 | Flavokawain B | 1775-97-9 | Flavokawain B, a chalcone isolated from the root extracts of kava-kava plant, is a potent apoptosis inducer for inhibiting the growth of various cancer cell lines. Flavokawain B shows strong antiangiogenic activity and inhibits human brain endothelial cell (HUVEC) migration and tube formation with very low and non-toxic concentrations[1][2]. |
CSN18396 | Episilvestrol | 697235-39-5 | Episilvestrol is a derivative of Silvestrol, which can induce apoptosis in LNCaP cells through the mitochondrial/apoptosome pathway without activation of executioner caspase-3 or -7 and a 5'myc-UTR-LUC inhibtor (IC50= 0.8 nM). |
CSN26431 | Dracorhodin perochlorate | 125536-25-6 | Dracorhodin perchlorate is a natural product extracted from a natural medicine Dragon's blood. Dracorhodin perchlorate inhibits cell proliferation, induces cell cycle arrest and apoptosis. |
CSN19958 | Columbianadin | 5058-13-9 | Columbianadin, a natural product isolated and purified from the herbs of Angelicae pubescens with analgesic, anti-inflammatory, calcium-channel blocking, and platelet aggregation inhibiting functions, can effectively suppress the growth of colon cancer cells, low concentration (up to 25 μM) of CBN induces apoptosis, and high concentration (50 μM) of CBN induces necroptosis, demonstrates that CBN has the potential to be a candidate in the development of anti-cancer agent derived from natural products. |
CSN23777 | BTR-1 | 18331-34-5 | BTR-1 is a rhodanine derivative induced cytotoxicity in a time- and concentration-dependent manner on leukemic cell line, leading to increased level of ROS production and DNA strand breaks suggesting activation of apoptosis for induction of cell death. |
CSN20352 | BDE-47 | 5436-43-1 | BDE-47 is an apoptosis inducer involving ROS mediated mitochondrial pathway and Nrf2 pathway activation. |
CSN25584 | Atractyloside potassium salt | 102130-43-8 | Atractyloside is a natural compound that acts both an inhibitor of ANT and an apoptosis inducer. |
CSN17056 | Apoptosis Activator 2 | 79183-19-0 | Apoptosis activator 2 is a potent apoptosis activator which increases procaspase-9 processing and subsequent caspase-3 activation. |
CSN10645 | 9-beta-Arabinosylguanine | 38819-10-2 | 9-beta-Arabinosylguanine is an inducer of apoptosis, inhibitor of DNA synthesis, an antimetabolite, and antineoplastic. |
CSN13311 | 3-O-Acetyloleanolic Acid | 4339-72-4 | 3-O-Acetyloleanolic Acid exhibits anti-angiogenic effects and induces apoptosis in HUVECs and HCT-116 cells, it is a natural product isolated and purified from the herbs of Phytolacca americana. |
CSN25117 | 2-methoxycinnamaldehyde | 1504-74-1 | 2-methoxycinnamaldehyde, found in ceylan cinnamon, is a flavouring ingredient. |
CSN18195 | (20S)-Protopanaxadiol | 30636-90-9 | (20S)-Protopanaxadiol is an aglycon metabolic derivative of the protopanaxadiol-type ginseng saponin and an apoptosis inducer. |