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Apoptosis Inducer

Apoptosis Inducer

货号 产品名 CAS号 信息
CSN19394 Ursonic Acid 6246-46-4 Ursolic acid, a naturally occurring triterpenoid, induces the apoptosis of human cancer cells through multiple signaling pathways.
CSN13084 Umbelliferone 93-35-6 Umbelliferone, a natural product isolated and purified from the herbs of Ruta graveolens L., exhibits significant anticancer effects via the induction of apoptosis, cell cycle arrest and DNA fragmentation in HepG2 cancer cells.
CSN21899 Ubiquitin Isopeptidase Inhibitor I, G5 108477-18-5 Ubiquitin Isopeptidase Inhibitor I, G5 is an apoptosome-independent caspase and apoptosis activator.
CSN29557 CLT-003   100823-03-8 TC11 is a potent inhibitor of tumor cell proliferation and an inducer of apoptosis via activation of caspase-3, 8 and 9.
CSN13130 Taurochenodeoxycholic Acid-D5 516-35-8 Taurochenodeoxycholic acid-d5 is a natural product.
CSN11500 SMIP004 143360-00-3 SMIP004 is an inducer of cancer-cell selective apoptosis of human prostate cancer cells, downregulates SKP2 and stabilizes p27.
CSN13728 Silvestrol 697235-38-4 Silvestrol is isolated from the fruits and twigs of Aglaia foveolata, by inducing caspase-3 activation to cause cell death.
CSN18642 Silvestrol Aglycone 960365-65-5 Silvestrol aglycone, an aglycone of potential anticancer rocaglate derivative from Aglaia foveolata, induces apoptosis in LNCaP cells through the mitochondrial/apoptosome pathway without activation of executioner caspase-3 or -7 and a 5'myc-UTR-LUC inhibtior (IC50= 0.8 nM).
CSN11911 Securinine 5610-40-2 Securinine, a natural product isolated and purified from the leaves and twigs of Securinega suffruticosa with antifungal activity, induces apoptosis in human leukemia HL-60 cells, is a promising monocytic differentiation inducing agent for Acute Myeloid Leukemia (AML).
CSN26530 Rabeprazole-d4 934295-48-4 Rabeprazole D4 (LY307640 D4) is a deuterium labeled Rabeprazole. Rabeprazole is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole induces apoptosis. Rabeprazole acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an IC50 of 0.3 μM. Rabeprazole can be used for the research of gastric ulcerations and gastroesophageal reflux[1][2][3].
CSN11798 Puromycin Aminonucleoside 58-60-6 Puromycin aminonucleoside is the aminonucleoside portion of the antibiotic puromycin and it is a puromycin analog which does not inhibit protein synthesis but induces apoptosis.. Puromycin aminonucleoside is a reversible inhibitor of dipeptidyl peptidase II and cytosol alanyl aminopeptidase.
CSN17239 NSC 348884 81624-55-7 NSC348884 is a nucleophosmin (NPM) inhibitor, inhibits cell proliferation and induce apoptosis in various cancer cell lines with IC50 values ranging from 1.4-4 µM.
CSN13525 Notopterol 88206-46-6 Notopterol induces apoptosis and inhibits cell cycle-specific, it's a natural product isolated and purified from the roots of Notopterygium incisum.
CSN20978 Myristicin 607-91-0 Myristicin is a natural product found in spices and umbelliferous plants. It induces apoptosis in leukemia cells, decreases pro-inflammatory cytokine expression in alveolar epithelial cells, and suppresses growth of Clostridium, Enterococcus, Candida.
CSN24150 Morin Hydrate 654055-01-3 Morin, a natural product isolated and purified from the root bark of Morus alba L., induces caspase-dependent apoptosis through extrinsic pathway by upregulating Fas receptor as well as through the intrinsic pathway by modulating Bcl-2 and IAP family members, and ROS generation.
CSN23859 Kinetin Riboside 4338-47-0 Kinetin riboside, a cytokinin analog, can induce apoptosis in cancer cells. It inhibits the proliferation of HCT-15 cells with an IC50 of 2.5 μM.
CSN11248 Karanjin 521-88-0 Karanjin, a natural product isolated and purified from the seeds of the karanja tree (Millettia pinnata or Pongamia glabra Vent.), has an effects on cell cycle arrest and apoptosis in human A549, HepG2 and HL-60 cancer cells.
CSN12309 Isoalantolactone 470-17-7 Isoalantolactone is a naturally occuring sesquiterpene lactone isolated from Inula helenium with a role as an apoptosis inducer, an antifungal agent and a plant metabolite.
CSN21006 Glaucocalyxin A 79498-31-0 Glaucocalyxin A can inhibit cell proliferation and promote apoptosis. It is extracted from the herbs of rabdosia rubescens.
CSN26414 Ginkgolide J 107438-79-9 Ginkgolide J is a main constituent of the non-flavone fraction of Ginkgo biloba with an IC50 range of 12-54 µM and shows neuroprotective and anti neuronal apoptotic ability[1][2].
CSN24957 Geranyl acetate 105-87-3 Geranyl acetate is a natural organic compound that is used primarily as a component of perfumes for creams and soaps and as a flavoring ingredient.
CSN26400 Flavokawain B 1775-97-9 Flavokawain B, a chalcone isolated from the root extracts of kava-kava plant, is a potent apoptosis inducer for inhibiting the growth of various cancer cell lines. Flavokawain B shows strong antiangiogenic activity and inhibits human brain endothelial cell (HUVEC) migration and tube formation with very low and non-toxic concentrations[1][2].
CSN19409 Evodiamine 518-17-2 Evodiamine, a natural product isolated and purified from the fruits of Evodia rutaecarpa (Juss.) Benth. with anti-oxidation, anti-inflammatory and anti-cancer effects, is an apoptosis inducer via the AKT pathway and an inhibitor of cancer cells proliferation via inhibition of MTDH expression and activation of apoptosis.
CSN18396 Episilvestrol 697235-39-5 Episilvestrol is a derivative of Silvestrol, which can induce apoptosis in LNCaP cells through the mitochondrial/apoptosome pathway without activation of executioner caspase-3 or -7 and a 5'myc-UTR-LUC inhibtor (IC50= 0.8 nM).
CSN26431 Dracorhodin perochlorate 125536-25-6 Dracorhodin perchlorate is a natural product extracted from a natural medicine Dragon's blood. Dracorhodin perchlorate inhibits cell proliferation, induces cell cycle arrest and apoptosis.
CSN19958 Columbianadin 5058-13-9 Columbianadin, a natural product isolated and purified from the herbs of Angelicae pubescens with analgesic, anti-inflammatory, calcium-channel blocking, and platelet aggregation inhibiting functions, can effectively suppress the growth of colon cancer cells, low concentration (up to 25 μM) of CBN induces apoptosis, and high concentration (50 μM) of CBN induces necroptosis, demonstrates that CBN has the potential to be a candidate in the development of anti-cancer agent derived from natural products.
CSN23777 BTR-1 18331-34-5 BTR-1 is a rhodanine derivative induced cytotoxicity in a time- and concentration-dependent manner on leukemic cell line, leading to increased level of ROS production and DNA strand breaks suggesting activation of apoptosis for induction of cell death.
CSN20352 BDE-47 5436-43-1 BDE-47 is an apoptosis inducer involving ROS mediated mitochondrial pathway and Nrf2 pathway activation.
CSN25584 Atractyloside potassium salt 102130-43-8 Atractyloside is a natural compound that acts both an inhibitor of ANT and an apoptosis inducer.
CSN17056 Apoptosis Activator 2 79183-19-0 Apoptosis activator 2 is a potent apoptosis activator which increases procaspase-9 processing and subsequent caspase-3 activation.
CSN13311 3-O-Acetyloleanolic Acid 4339-72-4 3-O-Acetyloleanolic Acid exhibits anti-angiogenic effects and induces apoptosis in HUVECs and HCT-116 cells, it is a natural product isolated and purified from the herbs of Phytolacca americana.
CSN25117 2-methoxycinnamaldehyde 1504-74-1 2-methoxycinnamaldehyde, found in ceylan cinnamon, is a flavouring ingredient.
CSN18195 (20S)-Protopanaxadiol 30636-90-9 (20S)-Protopanaxadiol is an aglycon metabolic derivative of the protopanaxadiol-type ginseng saponin and an apoptosis inducer.
CSN15676 Ergosterol peroxide 2061-64-5
CSN28923 Bleomycin A5 HCl 55658-47-4
CSN29107 Epipodophyllotoxin 4375-07-9
CSN33039 Bleomycin sulfate(1:x) 9041-93-4
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