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货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN23470 | 2-Aminopentanoic acid | 760-78-1 | H-DL-Nva-OH is the derivative of L-norvaline which is an inhibitor of arginase. |
CSN19711 | CB-1158-analog | 1345810-21-0 | CB-1158 is a potent arginase inhibitor. CB-1158 has the potential for anti-tumor activity in renal cell cancer, breast cancer, non-small cell lung cancer, acute myeloid leukemia, and other tumor types where arginase-secreting MDSCs are known to play an immunosuppressive role. |
CSN22364 | CB-1158 HCl | N/A | CB-1158 HCl is a potent and orally bioavailable inhibitor of arginase, with IC50s of 86 and 296 nM for recombinant human arginase 1 and 2, respectively. |
CSN18781 | BEC HCl | 222638-67-7 | BEC HCl is a competitive arginase inhibitor with Ki of 0.31 μM and 0.4-0.6 μM for Arginase II and rat Arginase I respectively. |
CSN17717 | Arginase inhibitor 1 | 1345808-25-4 | Arginase inhibitor 1 is a potent small molecule inhibitor of human arginases I and II with IC50s of 223 and 509 nM, respectively. |
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