Aromatase | Endocrinology/Hormones| CSNpharm

Aromatase

Aromatase
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货号	产品名	CAS号	信息
CSN24635	YM 511	148869-05-0	YM 511 is an orally active, potent aromatase (CYP19) inhibitor with IC50 of 0.4 and 0.12 nM at rat ovary and human placenta cells respectively.
CSN15878	Urolithin B	1139-83-9	Urolithin B is a natural product with anti-proliferative and antioxidant activity, which can penetrate the blood-brain barrier and may have neuroprotective effects against Alzheimer’s Disease.It inhibits aromatase activity in human placental microsomes and aromatase-sensitive MCF-7 (MCF-7aro) human breast cancer cells when used at concentrations of 47 and 4.7 µM, respectively.
CSN15677	Obacunone	751-03-1	Obacunone, a natural product isolated and purified from the barks of Phellodendron chinense, has cytotoxicity in androgen-dependent human prostate cancer cells. Obacunone may have the potential to prevent estrogen-responsive breast cancer through inhibition of the aromatase enzyme and inflammatory pathways, as well as activation of apoptosis.
CSN10978	Fadrozole	102676-47-1	Fadrozole is a selective aromatase inhibitor that has been introduced in Japan for the treatment of breast cancer.
CSN19726	Fadrozole HCl	102676-31-3	Fadrozole HCl specifically inhibits aromatase, blocking the aromatization of androstenedione and testosterone into estrone and estradiol, respectively.