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ATM/ATR

ATM/ATR

货号 产品名 CAS号 信息
CSN15844 KU-60019 925701-46-8 KU-60019 is an improved analogue of KU-55933, with IC50 of 6.3 nM for ATM.
CSN17142 CP-466722 1080622-86-1 CP-466722, a potent and reversible ATM inhibitor, does not affect ATR and inhibits PI3K or PIKK family members in cells.
CSN21930 Chloroquine Phosphate 1446-17-9 Chloroquine Phosphate is the phosphate salt of chloroquine, a quinoline compound with antimalarial and anti-inflammatory properties and inhibits the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin.
CSN13686 Chloroquine Diphosphate 50-63-5 Chloroquine Diphosphate is an inhibitor of autophagy/lysosome and Toll-like receptor (TLR) signalling, also acting as an ATM acitivator, it's an antimalarial drug.
CSN25554 Chloroquine Sulphate 132-73-0 Chloroquine Diphosphate is an inhibitor of autophagy/lysosome and Toll-like receptor (TLR) signalling, also acting as an ATM acitivator, it's an antimalarial drug.
CSN25650 Chloroquine 54-05-7 Chloroquine Diphosphate is an inhibitor of autophagy/lysosome and Toll-like receptor (TLR) signalling, also acting as an ATM acitivator, it's an antimalarial drug.
CSN16057 CGK733 905973-89-9 CGK 733 is an inhibitor of ATM and ATR with IC50 of ~200 nM, also induces cell death in prematurely senescent breast cancer cells.
CSN23317 AZD1390 2089288-03-7 AZD1390 is an ATM inhibitor with IC50 of 0.78 nM in cells.
CSN22539 AZ32 2288709-96-4 AZ32 is an ATM inhibitor with IC50 <6.2 nM in enzyme assays and 310 nM in cellular assays.
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