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Beta-lactamases are enzymes produced by bacteria that provide multi-resistance to β-lactam antibiotics such as penicillins, cephalosporins, cephamycins, and carbapenems (ertapenem), although carbapenems are relatively resistant to beta-lactamase. Beta-lactamase provides antibiotic resistance by breaking the antibiotics' structure.

β-lactamase

货号 产品名 CAS号 信息
CSN11999 Sulbactam Sodium 69388-84-7 Sulbactam sodium is an irreversible β-lactamase inhibitor.
CSN26395 K-252c 85753-43-1 K-252c, a staurosporine analog isolated from Nocardiopsis sp., is a cell-permeable PKC inhibitor, with an IC50 of 2.45 µM. K-252c induces apoptosis in human chronic myelogenous leukemia cancer cells. K-252c also inhibits β-lactamase, chymotrypsin, and malate dehydrogenase, with IC50 values of 8, 8 and 10 μM respectively[1][2][3].
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