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BCRP
货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN17725 | YHO-13351 | 1346753-00-1 | YHO-13351 is the water-soluble prodrug of YHO-13177, which is a potent and specific inhibitor of BCRP. |
CSN18565 | YHO-13351 free base | 912288-64-3 | YHO-13351 free base is the water-soluble prodrug of YHO-13177, which is a potent and specific inhibitor of BCRP. |
CSN18564 | YHO-13177 | 912287-56-0 | YHO-13177 is a selective and potent inhibitor of BCRP, it potentiates the cytotoxicity of SN-38 in cancer cells and has no effect on P-glycoprotein–mediated paclitaxel resistance in MDR1-transduced human leukemia K562 cells. |
CSN20009 | ML753286 | 1699720-89-2 | ML753286 is a potent inhibitor for BCRP, but not for P-glycoprotein (P-gp), organic anion-transporting polypeptide (OATP), or major cytochrome P450s (CYPs). |
CSN17368 | KS176 | 1253452-78-6 | KS176 is a potent and selective inhibitor for the breast cancer resistance protein (BCRP) multidrug transporter with IC50s of 0.59 and 1.39 μM in Pheo A and Hoechst 33342 assays respectively. |
CSN13172 | Ko 143 | 461054-93-3 | Ko 143 is a practical breast cancer resistance protein multidrug transporter inhibitor BCRP, with the EC90 value of 26 nM. |
CSN21978 | Glafenine hydrochloride | 65513-72-6 | Glafenine hydrochloride is a non-narcotic analgesic and non-steroidal anti-inflammatory drug and an ABCG2 inhibitor with an IC50 of 3.2 μM. |
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