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β-catenin

β-catenin

货号 产品名 CAS号 信息
CSN17476 WAY-262611 1123231-07-1 WAY-262611 is an agonist of β-Catenin and can increase bone formation rate with EC50 of 0.63 μM.
CSN19412 Triptonide 38647-11-9 Triptonide, a natural product isolated and purified from the herb of Tripterygium wilfordii Hook.f. with antileukemic, antitumor, anti-inflammatory activities, is effective in the treatment of autoimmune diseases. Triptonide can effectively inhibit canonical Wnt/β-catenin signaling by targeting the downstream C-terminal transcription domain of β-catenin or a nuclear component associated with β-catenin.
CSN11885 Salinomycin 53003-10-4 Salinomycin, an antibiotic potassium ionophore, is an anti-coccidial drug and an autophagy modulator. It is also an inhibitor of Wnt/β-catenin signaling.
CSN11650 Pamidronic Acid 40391-99-9 Pamidronic Acid is a an amino- bisphosphonate used to prevent bone loss and treat osteoporosis.
CSN33101 NRX-103094 N/A NRX-103094, a molecular glue, is a potent enhancer of the interaction between β-catenin, and its cognate E3 ligase, SCFβ-TrCP. NRX-103094 enhances the binding of pSer33/Ser37 β-catenin peptide for β-TrCP with an EC50 of 62 nM and a Kd of 0.6 nM.
CSN20582 KY1220 292168-79-7 KY1220 inhibits Wnt/β-catenin pathway with IC50 of 2.1 μM in HEK293 cells and it can destabilize both β-catenin and Ras.
CSN22363 C-82 1422253-37-9 C-82 is an active metabolite of PRI-724 which selectively inhibits the CBP/β-catenin interaction.
CSN20163 BC2059 1227637-23-1 beta-Catenin inhibitor BC2059 is efficacious as monotherapy or in combination with proteasome inhibitor bortezomib in multiple myeloma.
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