Beta-catenin | Cytoskeleton|Stem Cells/Wnt| CSNpharm

β-catenin

β-catenin
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货号	产品名	CAS号	信息
CSN17476	WAY-262611	1123231-07-1	WAY-262611 is an agonist of β-Catenin and can increase bone formation rate with EC50 of 0.63 μM.
CSN11650	Pamidronic Acid	40391-99-9	Pamidronic Acid is a an amino- bisphosphonate used to prevent bone loss and treat osteoporosis.
CSN33101	NRX-103094	N/A	NRX-103094, a molecular glue, is a potent enhancer of the interaction between β-catenin, and its cognate E3 ligase, SCFβ-TrCP. NRX-103094 enhances the binding of pSer33/Ser37 β-catenin peptide for β-TrCP with an EC50 of 62 nM and a Kd of 0.6 nM.
CSN20582	KY1220	292168-79-7	KY1220 inhibits Wnt/β-catenin pathway with IC50 of 2.1 μM in HEK293 cells and it can destabilize both β-catenin and Ras.
CSN22363	C-82	1422253-37-9	C-82 is an active metabolite of PRI-724 which selectively inhibits the CBP/β-catenin interaction.
CSN20163	BC2059	1227637-23-1	beta-Catenin inhibitor BC2059 is efficacious as monotherapy or in combination with proteasome inhibitor bortezomib in multiple myeloma.