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β-catenin

β-catenin

货号 产品名 CAS号 信息
CSN27594 β-catenin-IN-2 1458664-10-2 β-catenin-IN-2 is a potent β-catenin inhibitor that can be used for the study of colorectal cancer.
CSN17476 WAY-262611 1123231-07-1 WAY-262611 is an agonist of β-Catenin and can increase bone formation rate with EC50 of 0.63 μM.
CSN19412 Triptonide 38647-11-9 Triptonide, a natural product isolated and purified from the herb of Tripterygium wilfordii Hook.f. with antileukemic, antitumor, anti-inflammatory activities, is effective in the treatment of autoimmune diseases. Triptonide can effectively inhibit canonical Wnt/β-catenin signaling by targeting the downstream C-terminal transcription domain of β-catenin or a nuclear component associated with β-catenin.
CSN19245 SKL2001 909089-13-0 SKL2001 is Wnt/β-catenin pathway agonist which interferes in the interaction of Axin/β-catenin.
CSN11885 Salinomycin 53003-10-4 Salinomycin, an antibiotic potassium ionophore, is an anti-coccidial drug and an autophagy modulator. It is also an inhibitor of Wnt/β-catenin signaling.
CSN20164 PP2A-β-Catenin Inhibitor CS-11 N/A PP2A-β-Catenin inhibitor CS-11 a small molecule inhibitor of PP2A-β-catenin signaling that limits both in vivo tumor growth and metastasis.
CSN11650 Pamidronicacid 40391-99-9 Pamidronic Acid is a an amino- bisphosphonate used to prevent bone loss and treat osteoporosis.
CSN33101 NRX-103094 2763260-36-0 NRX-103094, a molecular glue, is a potent enhancer of the interaction between β-catenin, and its cognate E3 ligase, SCFβ-TrCP. NRX-103094 enhances the binding of pSer33/Ser37 β-catenin peptide for β-TrCP with an EC50 of 62 nM and a Kd of 0.6 nM.
CSN20582 KY1220 292168-79-7 KY1220 inhibits Wnt/β-catenin pathway with IC50 of 2.1 μM in HEK293 cells and it can destabilize both β-catenin and Ras.
CSN12696 (6S)-N-Benzyl-6-(4-hydroxybenzyl)-8-(naphthalen-1-ylmethyl)-4,7-dioxohexahydro-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide 868774-16-7 ICG-001 is an inhibitor of β-catenin/cyclic AMP responsive element binding protein binding protein (CBP)-mediated transcription with IC50 of 3 µM.
CSN22363 (6S,9S,9aS)-N-Benzyl-6-(4-hydroxybenzyl)-2,9-dimethyl-4,7-dioxo-8-(quinolin-8-ylmethyl)hexahydro-2H-pyrazino[2,1-c][1,2,4]triazine-1(6H)-carboxamide 1422253-37-9 C-82 is an active metabolite of PRI-724 which selectively inhibits the CBP/β-catenin interaction.
CSN20163 Tegatrabetan 1227637-23-1 beta-Catenin inhibitor BC2059 is efficacious as monotherapy or in combination with proteasome inhibitor bortezomib in multiple myeloma.
CSN35374 NRX-252262 2438637-61-5
CSN36240 5,7,3',4'-Tetramethoxyflavone 855-97-0
CSN42991 K-756 130017-40-2
CSN62104 Coronaridine 467-77-6
CSN62592 Teplinovivint 1428064-91-8
CSN62476 UU-T02 1500080-17-0
CSN66349 CCT031374 HBr 1219184-91-4
CSN69073 NRX-252114 2763260-39-3
CSN79371 NRX-1933 2763260-30-4
CSN85582 YW1128 2131223-64-6
CSN108083 YH249 2141977-22-0
CSN107818 UU-T03 1586007-00-2
CSN51574 2-((5-((4-Ethylphenoxy)methyl)-4-(1-phenylethyl)-4H-1,2,4-triazol-3-yl)thio)cyclopentanone 1011440-46-2
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