Bradykinin Receptor

Bradykinin Receptor
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货号	产品名	CAS号	信息
CSN24303	Lobradimil	159768-75-9	Labradimil, also known as RMP 7, is a bradykinin B2 receptor agonist potentially for the treatment of brain cancer. RMP-7) increases the permeability of human brain microvascular endothelial cell monolayers. RMP-7 enhances delivery of hydrophilic chemotherapeutics and increases survival in rats with metastatic tumors in the brain. RMP-7 increases carboplatin levels in brain tumors after pretreatment with dexamethasone.
CSN11154	Icatibant	130308-48-4	Icatibant is a selective and specific antagonist of bradykinin B2 receptor with IC50 and Ki of 1.07 nM and 0.798 nM respectively.
CSN23822	Icatibant Acetate	138614-30-9	Icatibant acetate (HOE-140 acetate) is a potent and specific peptide antagonist of bradykinin B2 receptor with IC50 and Ki of 1.07 nM and 0.798 nM respectively.
CSN21292	FR167344	215258-13-2	FR167344 free base is an orally active, nonpeptide bradykinin receptor B2 antagonist. FR167344 free base shows a high affinity binding to the B2 receptor with an IC50value of 65 nM and no binding affinity for the B1 receptor.
CSN18567	ELN-441958	913064-47-8	ELN-441958 is a potent, neutral antagonist of B1 receptor, inhibits the binding of the B1 agonist ligand [3H]DAKD to IMR-90 cells with Ki of 0.26 nM.