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c-Kit

c-Kit

货号 产品名 CAS号 信息
CSN26936 1-(4-((6-Amino-5-((methoxyimino)methyl)pyrimidin-4-yl)oxy)-2-chlorophenyl)-3-ethylurea 951151-97-6 JNJ-38158471 is a well tolerated, orally available, highly selective VEGFR-2 inhibitor, with an IC50 of 40 nM. JNJ-38158471 also inhibits Ret and Kit with IC50s of 180 and 500 nM, respectively .
CSN20497 ISCK03 945526-43-2 ISCK03 is a cell-permeable c-Kit inhibitor with IC50 < < 2.5 μM in cell-free kinase assays and blocks SCF-induced c-kit and Erk phosphorylation (1 μM causes > 90% inhibition) without any effect on HGF-induced Erk phosphorylation in 501mel melanoma cells, it's a phenyl-imidazolosulfonamide compound.
CSN16807 Imatinib Mesylate 220127-57-1 Imatinib Mesylate is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively.
CSN11190 Imatinib   152459-95-5 Imatinib is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM in cell-free or cell-based assays, respectively.
CSN11190 Imatinib   152459-95-5 Imatinib is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM in cell-free or cell-based assays, respectively.
CSN12808 Dovitinib Lactate 692737-80-7 Dovitinib lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) with an IC50 of 5 nM.
CSN22109 Ripretinib 1442472-39-0 DCC-2618 is a pan-KIT and PDGFRA inhibitor, and has antitumor activity.
CSN16127 Amuvatinib 850879-09-3 Amuvatinib is a potent and multi-targeted inhibitor that inhibits c-Kit, PDGFRα and Flt3 with IC50 of 10, 40 and 81 nM respectively.
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