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c-RET
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN26135 | RETV804M kinase inhibitor | 2414909-94-5 | RETV804M kinase inhibitor is a selective c-RET (V804M) inhibitor with IC50 value of 20nM. |
| CSN13099 | Regorafenib | 755037-03-7 | Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50 of 13/4.2/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively. |
| CSN26936 | 1-(4-((6-Amino-5-((methoxyimino)methyl)pyrimidin-4-yl)oxy)-2-chlorophenyl)-3-ethylurea | 951151-97-6 | JNJ-38158471 is a well tolerated, orally available, highly selective VEGFR-2 inhibitor, with an IC50 of 40 nM. JNJ-38158471 also inhibits Ret and Kit with IC50s of 180 and 500 nM, respectively . |
| CSN27593 | DUN73423 | 2414373-42-3 | DUN73423 is a RET/KDR-Selective inhibitor of RETV804M Kinase with IC50 of 7 nM. |
| CSN18365 | AST-487 | 630124-46-8 | AST-487 is a RET kinase inhibitor with IC50 of 880 nM, inhibits RET autophosphorylation and activation of downstream effectors, also inhibits Flt-3 with IC50 of 520 nM. |
| CSN22316 | AD80 | 1384071-99-1 | AD80 is a multikinase inhibitor with inhibitions on RET, RAF, SRC and S6K. |