c-RET | Apoptosis|Protein Tyrosine Kinase/RTK| CSNpharm

c-RET

c-RET
第页，共 1 页

货号	产品名	CAS号	信息
CSN27593	DUN73423	2414373-42-3	DUN73423 is a RET/KDR-Selective inhibitor of RETV804M Kinase with IC50 of 7 nM.
CSN28779	BT13	924537-98-4	BT13 acts as direct RetA agonists and interacts with GFRα1 at the allosteric site in GDNF-GFRα1-RetA complex. It was similar to NGF and ARTN in selectively promoting neurite outgrowth from the peptidergic class of adult sensory neurons in culture, but was opposite to ARTN in causing neurite elongation without affecting initiation.
CSN18365	AST-487	630124-46-8	AST-487 is a RET kinase inhibitor with IC50 of 880 nM, inhibits RET autophosphorylation and activation of downstream effectors, also inhibits Flt-3 with IC50 of 520 nM.