c-RET | Apoptosis|Protein Tyrosine Kinase/RTK| CSNpharm

c-RET

c-RET
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货号	产品名	CAS号	信息
CSN26135	RETV804M kinase inhibitor	2414909-94-5	RETV804M kinase inhibitor is a selective c-RET (V804M) inhibitor with IC50 value of 20nM.
CSN13099	Regorafenib	755037-03-7	Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50 of 13/4.2/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively.
CSN26936	1-(4-((6-Amino-5-((methoxyimino)methyl)pyrimidin-4-yl)oxy)-2-chlorophenyl)-3-ethylurea	951151-97-6	JNJ-38158471 is a well tolerated, orally available, highly selective VEGFR-2 inhibitor, with an IC50 of 40 nM. JNJ-38158471 also inhibits Ret and Kit with IC50s of 180 and 500 nM, respectively .
CSN27593	DUN73423	2414373-42-3	DUN73423 is a RET/KDR-Selective inhibitor of RETV804M Kinase with IC50 of 7 nM.
CSN18365	AST-487	630124-46-8	AST-487 is a RET kinase inhibitor with IC50 of 880 nM, inhibits RET autophosphorylation and activation of downstream effectors, also inhibits Flt-3 with IC50 of 520 nM.
CSN22316	AD80	1384071-99-1	AD80 is a multikinase inhibitor with inhibitions on RET, RAF, SRC and S6K.