Calcineurin

Calcineurin
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货号	产品名	CAS号	信息
CSN15684	Tacrolimus	104987-11-3	Tacrolimus is a potent immunosuppressive drug often administered to transplant recipient patients and exhibits a variety of adverse cardiovascular effects. Its mechanism of action involves the formation of a high affinity complex (Ki = 0.2 nM) with FK-506 binding protein 12 (FKBP12).
CSN12789	Tacrolimus Monohydrate	109581-93-3	Tacrolimus is a potent immunosuppressive drug often administered to transplant recipient patients and exhibits a variety of adverse cardiovascular effects. Its mechanism of action involves the formation of a high affinity complex (Ki = 0.2 nM) with FK-506 binding protein 12 (FKBP12).
CSN12264	Pimecrolimus	137071-32-0	Pimecrolimus is an immunomodulating agent of the calcineurin inhibitor class， effective in various inflammatory skin diseases, including seborrheic dermatitis, cutaneous lupus erythematosus, oral lichen planus, vitiligo and psoriasis.
CSN10724	Cyclosporine	79217-60-0	Cyclosporine is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation.
CSN19509	Cyclosporine A	59865-13-3	Cyclosporine A is an immunosuppressive agent, binds to the cyclophilin and then inhibits calcineurin with IC50 of 7 nM.