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Calcium Channel
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN25647 | Verapamil | 52-53-9 | Verapamil is a phenylalkylamine class L-type calcium channel blocker. It may be a potential Covid-19 drug. |
| CSN27384 | Urolithin C | 165393-06-6 | Urolithin C, a gut-microbial metabolite of Ellagic acid, is a glucose-dependent activator of insulin secretion. Urolithin C is a L-type Ca2+ channel opener and enhances Ca2+ influx. Urolithin C induces cell apoptosis through a mitochondria-mediated pathway and also stimulates reactive oxygen species (ROS) formation. |
| CSN23849 | TTA-A8 | 1146395-46-1 | TTA-A8 is an antagonist of T-type calcium channels. |
| CSN16638 | Taurine | 107-35-7 | Taurine is a widely distributed organic compound in animal tissues which possesses function of conjugation of bile acids, antioxidation, osmoregulation, membrane stabilization, and modulation of calcium signaling. |
| CSN22916 | Gadolinium chloride | 10138-52-0 | Stretch-activated calcium channel blocker; calcium-sensing receptor agonist |
| CSN22176 | 18:0 LYSO-PE | 69747-55-3 | Stearoyl lysophosphatidylethanolamine is an agent that can induce [Ca2+]i increase. |
| CSN21359 | SQ-31765 | 138383-07-0 | SQ-31765 is a benzazepine calcium channel blocker. |
| CSN24655 | SAK3 | 1256269-87-0 | SAK 3 is a effective activator of CaV3.1 and CaV3.3. |
| CSN20495 | S107 | 927871-76-9 | S107 is a RyR-selective 1,4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels. |
| CSN21356 | S107 hydrochloride | 1357476-46-0 | S107 HCl is a RyR-selective 1,4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels. |
| CSN24653 | Ryanodine | 15662-33-6 | Ryanodine is an inhibitor of Ca2+ release from sarcoplasmic reticulum with IC50 values of 10 and 2.8 nM in skeletal and cardiac muscle respectively. |
| CSN23345 | Ruthenium red | 11103-72-3 | Ruthenium red, a polycationic dye, is an inhibitor of voltage sensitive calcium channel and used in histology to stain aldehyde fixed. |
| CSN11841 | Rhynchophylline | 76-66-4 | Rhyncholphylline, an alkaloid isolated and purified from the herbs of Uncaria rhynchophylla., can protect against ischemic damage and glutamate-induced neuronal death, and also inhibit MA impairment in cultured neurons in vitro. Ca2+ channel blocker. |
| CSN14166 | Reticuline | 485-19-8 | Reticuline, a natural product isolated and purified from the root of Thalictrum foliolosum, elicits vasorelaxation probably due to the blockade of the L-type voltage-dependent Ca(2+) current in rat aorta. |
| CSN12787 | Ranolazine dihydrochloride | 95635-56-6 | Ranolazine 2HCl is a calcium uptake inhibitor via the sodium/calcium channal, used to treat chronic angina. |
| CSN29534 | Pranidipine | 99522-79-9 | Pranidipine is an effective, long-acting 1,4-dihydropyridine calcium channel blocker. It also has antihypertensive activity. |
| CSN27750 | NS-638 | 150493-34-8 | NS-638 is nonpeptide Ca2+-channel blocker with IC50 value of 3.4μM for blocking K+-stimulated intracellular Ca2+-elevation. |
| CSN11555 | Nifedipine | 21829-25-4 | Nifedipine is a dihydropyridine calcium channel blocker, used to lower hypertension and to treat angina. |
| CSN16159 | Neomycin sulfate | 28002-70-2 | Neomycin Trisulfate Salt is an aminoglycoside antibiotic and calcium channel protein inhibitor. |
| CSN22225 | NecroX-5 | 1383718-29-3 | NecroX-5 is a derivative of the NecroX, reduces intracellular calcium concentration, and possesses anti-inflammatory and anti-cancer activity. |
| CSN27383 | Levamlodipine | 103129-82-4 | Levamlodipine ((S)-Amlodipine) is a powerful dihydropyridine calcium channel blocker, possessing vasodilation properties and used in the treatment of hypertension and angina. |
| CSN21704 | Lemildipine | 94739-29-4 | Lemildipine is a 1,4-dihydropyridine calcium channel blocker which has potential to treat hypertension and cerebrovascular ischemia. |
| CSN23827 | Lanthanum(III) chloride heptahydrate | 10025-84-0 | Lanthanum(III) Chloride Heptahydrate is a calcium channel blocker. |
| CSN12998 | Lamotrigine | 84057-84-1 | Lamotrigine is a member of the sodium channel blocking class of antiepileptic drugs which can block L-, N-, and P-type calcium channels and has weak 5-HT3 receptor inhibition. |
| CSN26862 | Isotachysterol 3 | 22350-43-2 | Isotachysterol 3 is an analog of 1,25-dihydrox Vitamin D3. Isotachysterol 3 stimulates intestinal calcium transport and bone calcium mobilization in anephric rats[1]. |
| CSN21683 | Iganidipine | 119687-33-1 | Iganidipine is a blocker of calcium channel that used for the treatment of glaucoma. |
| CSN17326 | Felodipine | 72509-76-3 | Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker. |
| CSN23604 | Tricaine methanesulfonate | 886-86-2 | Ethyl 3-Aminobenzoate Methanesulfonate, a hydrophilic derivative of benzocaine, is an anesthetic. |
| CSN10948 | Ethosuximide | 77-67-8 | Ethosuximide is used to treat absence seizures. |
| CSN21615 | Dopropidil | 79700-61-1 | Dopropidil is a modulator of intracellular calcium with antagonist activity and anti-anginal effects. |
| CSN20804 | DHBP dibromide | 6159-05-3 | DHBP is a calcium release inhibitor and a muscle relaxant. |
| CSN36339 | Dehydronitrosonisoldipine | 87375-91-5 | Dehydronitrosonisoldipine, a derivative of Nisoldipine, is an calcium channel antagonist. |
| CSN21592 | Darodipine | 72803-02-2 | Darodipine is an antagonist of calcium channel. |
| CSN20956 | Cycleanine | 518-94-5 | Cycleanine, isolated from stephania, is a selective antagonist of vascular calcium. |
| CSN26332 | Carboxyamidotriazole | 99519-84-3 | Carboxyamidotriazole is a blocker of non-voltage dependent calcium channel with anti-inflammatory activity. |
| CSN22911 | CaCCinh-A01 | 407587-33-1 | CaCCinh-A01 is a dual inhibitor of TMEM16A and calcium-activated chloride channel (CaCC) with IC50s of 2.1 and 10 μM respectively. |
| CSN22110 | Bepridil hydrochloride | 68099-86-5 | Bepridil HCl is a calcium channel blocker, with antianginal activity. |
| CSN26603 | Barnidipine | 104713-75-9 | Barnidipine is a calcium channel blocker. |
| CSN27668 | Azumolene | 64748-79-4 | Azumolene, an analog of dantrolene, is a muscle relaxant that inhibits the release of calcium from skeletal muscle sarcoplasmic reticulum by modulating the activity of the SR ryanodine receptor (RyR) Ca2+ release channel. |
| CSN24052 | ACT-709478 | 1838651-58-3 | ACT-709478 is a potent, selective, orally-bioavailable and brain penetrant T-type calcium channel blocker with IC50 of 6.4, 18, and 7.5 nM for Cav3.1, Cav3.2, and Cav3.3 channels respectively. |
| CSN23743 | Calcimycin | 52665-69-7 | A23187 is a divalent cation ionophore commonly used to facilitate the movement of Ca2+ into cells, triggering the activation of intracellular calcium-dependent pathways. |
| CSN27385 | 1-Octanol | 111-87-5 | 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents. 1-Octanol is a highly attractive biofuel with diesel-like properties. |
| CSN14536 | 1-Hydroxy-2,3,5-Trimethoxyxanthone | 22804-49-5 | 1-Hydroxy-2, 3, 5-trimethoxyxanthone, a natural product isolated and purified from the herb of Halenia elliptica D. |
| CSN79732 | (3R)-5-(3-chloro-4-fluorophenyl)-3-methyl-3-(pyrimidin-5-ylmethyl)-1-(1H-1,2,4-triazol-3-yl)-1,3-dihydro-2H-indol-2-one | 1309601-26-0 | |
| CSN97371 | (2S,3aS,7aS)-1-((S)-2-(((S)-1-Ethoxy-1-oxopentan-2-yl)amino)propanoyl)octahydro-1H-indole-2-carboxylic acid compound with (S)-2-amino-5-guanidinopentanoic acid (1:1) | 612548-45-5 | |
| CSN106147 | (R)-3-(2-Chlorophenyl)-N-(1-(3-methoxyphenyl)ethyl)propan-1-amine | 148717-54-8 |
