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CaMK

CaMK

货号 产品名 CAS号 信息
CSN26523 Verosudil 1414854-42-4 Verosudil, also known as AR-12286, is a potent and selective Rho kinase inhibitor. AR-12286 was well tolerated and provided statistically significant reduction in IOP (intraocular pressure) in patients with XFS (exfoliation syndrome) and OHT (ocular hypertension) or XFG (exfoliative glaucoma). This drug may represent an additional therapeutic paradigm for the treatment of XFG.
CSN19242 STO-609 52029-86-4 STO-609 is a specific inhibitor of the Ca2+/Calmodulin-dependent protein kinase kinase (CaM-KK) that inhibits the activities of recombinant CaM-KKα and CaM-KKβ isoforms, with Ki values of 80 and 15 ng/mL, respectively, and also inhibits their autophosphorylation activities.
CSN20312 SMP-114 215174-50-8 SMP-114 is a CaMKII inhibitor with oral bioavailability and mediates the reduction SR Ca(2+) leak and arrhythmogenic cellular correlates.
CSN16664 NH125 278603-08-0 NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, also a potent histidine kinase inhibitor.
CSN18794 KN-93 Phosphate 1188890-41-6 KN-93 Phosphate, a potent Ca2+/calmodulin-dependent protein kinase II (CaMKII) selective inhibitor with Ki of 370 nM, is the water soluble version of KN-93.
CSN19063 KN-93 Phosphate(Random Configuration) 1913269-12-1 KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM).
CSN11255 KN-93 139298-40-1 KN-93 is a potent Ca2+/calmodulin-dependent protein kinase II (CaMKII) selective inhibitor with Ki of 370 nM.
CSN16900 KN-93 HCl 1956426-56-4 KN-93 HCl is a membrane-permeant synthetic inhibitor of purified neuronal CaMK-II, with Ki of 370 nM.
CSN16913 KN-92 Phosphate 1135280-28-2 KN-92 phosphate is an inactive derivative of KN-93. KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM).
CSN19064 KN-92 176708-42-2 KN-92 is an inactive derivative of KN-93. KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM).
CSN17850 KN-92 HCl 1431698-47-3 KN-92 HCl a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM).
CSN16150 K252a 99533-80-9 K252a is an alkaloid isolated from Nocardiopisis sp. soil fungi. This staurosporine analog is a highly potent cell permeable inhibitor of CaM kinase and phosphorylase kinase (IC50 = 1.8 and 1.7 nmol/L, respectively).
CSN16150 K252a 99533-80-9 K252a is an alkaloid isolated from Nocardiopisis sp. soil fungi. This staurosporine analog is a highly potent cell permeable inhibitor of CaM kinase and phosphorylase kinase (IC50 = 1.8 and 1.7 nmol/L, respectively).
CSN22017 CV-159 86384-98-7 CV-159 is a unique dihydropyridine Ca2+ antagonist with an anti-calmodulin (CaM) action and shows antiinflammatory activities.
CSN22547 CRT0066101 1883545-60-5 CRT0066101 reduces BrdU incorporation, increases apoptosis, blocks neurotensin (NT)-induced PKD1/2 activation, reduces NT-induced PKD-mediated Hsp27 phosphorylation, attenuates PKD1-mediated NF-κB activation, and abrogates expression of NF-κB-dependent-dependent proliferative and pro-survival proteins.
CSN22740 Camstatin 1002295-95-5 Camstatin is a calmodulin antagonist.
CSN21543 Calmodulin-Dependent Protein Kinase II (290-309) 115044-69-4 Calmodulin-dependent protein kinase II (290-309) is a potent inhibitor of Ca2+/calmodulin-dependent protein kinase II.
CSN23191 W-5 HCl 61714-25-8 Calmodulin antagonist
CSN23190 W-13 HCl 88519-57-7 Calmodulin antagonist
CSN23192 W-9 HCl 69762-85-2 Calmodulin antagonist
CSN22737 Calmidazolium Chloride 57265-65-3 Calmidazolium Chloride is a calmodulin antagonist.
CSN10418 Berbamine HCl 6078-17-7 Berbamine 2HCl, a natural product isolated and purified from the roots of Cocculus orbiculatus (L.) DC., has high binding affinity toward the (GGA)8 G-quadruplex, and is a promising agent to suppress liver cancer growth by targeting CAMKII.
CSN22694 Autocamtide-2-related inhibitory peptide, myristoylated 201422-04-0 Autocamtide-2-related Inhibitory Peptide, myristoylated is a CaM kinase II inhibitor that enhances cell permeable derivative of Autocamtide-2-related inhibitory peptide.
CSN22693 Autocamtide-2-related Inhibitory Peptide 167114-91-2 Autocamtide-2-related Inhibitory Peptide is a selective and potent calmodulin-dependent protein kinase II (CaM kinase II) inhibitor with IC50 of 40 nM.
CSN20471 Arcyriaflavin A 118458-54-1 Arcyriaflavin A is a potent inhibitor of cdk4/cyclin D1 (IC50 = 59 nM) and CaM kinase II (IC50 = 25 nM) but displays selectivity over several other kinases in vitro (IC50 values for inhibition of PKA and PKC are > 2 and > 100 μM respectively). It can also inhibit human cytomegalovirus (HCMV) replication in vitro (IC50 = 200 nM).
CSN22660 A-7 HCl 79127-24-5 A-7 HCl is a potent calmodulin antagonist.
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