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CaMK
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN19242 | STO-609 | 52029-86-4 | STO-609 is a specific inhibitor of the Ca2+/Calmodulin-dependent protein kinase kinase (CaM-KK) that inhibits the activities of recombinant CaM-KKα and CaM-KKβ isoforms, with Ki values of 80 and 15 ng/mL, respectively, and also inhibits their autophosphorylation activities. |
| CSN20312 | SMP-114 | 215174-50-8 | SMP-114 is a CaMKII inhibitor with oral bioavailability and mediates the reduction SR Ca(2+) leak and arrhythmogenic cellular correlates. |
| CSN16664 | NH125 | 278603-08-0 | NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, also a potent histidine kinase inhibitor. |
| CSN21344 | Methophenazine | 388-51-2 | Metofenazate is a selective calmodulin inhibitor. |
| CSN18794 | KN-93 Phosphate | 1188890-41-6 | KN-93 Phosphate, a potent Ca2+/calmodulin-dependent protein kinase II (CaMKII) selective inhibitor with Ki of 370 nM, is the water soluble version of KN-93. |
| CSN11255 | KN-93 | 139298-40-1 | KN-93 is a potent Ca2+/calmodulin-dependent protein kinase II (CaMKII) selective inhibitor with Ki of 370 nM. |
| CSN16913 | KN-92 Phosphate | 1135280-28-2 | KN-92 phosphate is an inactive derivative of KN-93. KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). |
| CSN19064 | KN-92 | 176708-42-2 | KN-92 is an inactive derivative of KN-93. KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). |
| CSN17850 | KN-92 HCl | 1431698-47-3 | KN-92 HCl a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). |
| CSN23191 | W-5 HCl | 61714-25-8 | Calmodulin antagonist |
| CSN23190 | W-13 HCl | 88519-57-7 | Calmodulin antagonist |
| CSN23192 | W-9 HCl | 69762-85-2 | Calmodulin antagonist |
| CSN22737 | Calmidazolium Chloride | 57265-65-3 | Calmidazolium Chloride is a calmodulin antagonist. |
| CSN10417 | Berbamine | 478-61-5 | Berbamine, a natural product isolated and purified from the roots of Cocculus orbiculatus (L.) DC., has high binding affinity toward the (GGA)8 G-quadruplex, and is a promising agent to suppress liver cancer growth by targeting CAMKII. |
| CSN10418 | Berbamine HCl | 6078-17-7 | Berbamine 2HCl, a natural product isolated and purified from the roots of Cocculus orbiculatus (L.) DC., has high binding affinity toward the (GGA)8 G-quadruplex, and is a promising agent to suppress liver cancer growth by targeting CAMKII. |
| CSN20471 | Arcyriaflavin A | 118458-54-1 | Arcyriaflavin A is a potent inhibitor of cdk4/cyclin D1 (IC50 = 59 nM) and CaM kinase II (IC50 = 25 nM) but displays selectivity over several other kinases in vitro (IC50 values for inhibition of PKA and PKC are > 2 and > 100 μM respectively). It can also inhibit human cytomegalovirus (HCMV) replication in vitro (IC50 = 200 nM). |
| CSN22660 | A-7 HCl | 79127-24-5 | A-7 HCl is a potent calmodulin antagonist. |
