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cAMP
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN20479 | ST034307 | 133406-29-8 | ST034307 is an adenylyl cyclase 1 (AC1) inhibitor (IC50 = 2.3 μM), which exhibits some selectivity for AC1 over other AC isoforms. |
| CSN11972 | SQ22536 | 17318-31-9 | SQ22536 is an inhibitor of adenylyl cyclase with an IC50 of 1.4 μM. It can inhibit PGE1-stimulated increases in cAMP levels in intact human platelets. |
| CSN21673 | PACAP (1-38), human, ovine, rat | 137061-48-4 | PACAP 1-38 is a potent PACAP receptor agonist with IC50s of 4 nM, 2 nM, and 1 nM for PACAP type I receptor, PACAP type II receptor VIP1, and PACAP type II receptor VIP2 respectively. |
| CSN26406 | NKH477 | 138605-00-2 | NKH477 is a novel water-soluble forskolin derivative that improves cardiac failure mainly through its beneficial effects on diastolic cardiac function. NKH477 is a potent activator of adenylyl cyclase and increases intracellular cAMP. NKH477 exerts an antiproliferative effect in vivo with an altered cytokine profile to inhibit the acute rejection of rat orthotopic lung allografts[1]. |
| CSN11051 | Forskolin | 66575-29-9 | Forskolin is a ubiquitous activator of eukaryotic adenylyl cyclase (AC) in a wide variety of cell types with binding (IC50=41 nM) to and activation (EC50=0.5 μM) of type I adenylyl cyclase. It is commonly used to raise levels of cAMP in the research of cell physiology. |
| CSN20413 | CB7921220 | 115453-99-1 | CB7921220 is an inhibitor of adenylyl cyclase isoform-1 (AC1) and isoform-6 (AC6). |
| CSN22739 | cAMPS-Rp, Triethylammonium Salt | 151837-09-1 | cAMPS-Rp, Triethylammonium Salt acts as a competitive antagonist of cAMP-induced activation of PKA (IC50 = 11 - 16 μM) by interacting with cAMP binding sites on the regulatory subunits. |
| CSN10469 | Bithionol | 97-18-7 | Bithionol is an anti-parasitic drug and can be used to inhibit solid tumor growth in several preclinical cancer models. |
| CSN25537 | Dideoxyadenosine | 4097-22-7 | 2′,3′-Dideoxyadenosine is a nucleoside analog of deoxyadenosine. It inhibits adenylyl cyclase and may play a key role in the inhibition of tumor progression. It is a potent inhibitor of reverse transcriptase enzyme of HIV. |
| CSN27244 | 2′,5′-Dideoxyadenosine | 6698-26-6 | 2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor via binding the P-site with an IC50 of 3 µM . 2',5'-Dideoxyadenosine is a nucleoside analog and exerts a potent antiadrenergic action in heart . |
| CSN19770 | 14-Deoxyandrographolide | 4176-97-0 | 14-Deoxyandrographolide, a natural product isolated and purified from the herbs of Andrographis paniculata (Burm. |
