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cAMP
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN20479 | ST034307 | 133406-29-8 | ST034307 is an adenylyl cyclase 1 (AC1) inhibitor (IC50 = 2.3 μM), which exhibits some selectivity for AC1 over other AC isoforms. |
| CSN11972 | SQ22536 | 17318-31-9 | SQ22536 is an inhibitor of adenylyl cyclase with an IC50 of 1.4 μM. It can inhibit PGE1-stimulated increases in cAMP levels in intact human platelets. |
| CSN21673 | PACAP (1-38), human, ovine, rat | 137061-48-4 | PACAP 1-38 is a potent PACAP receptor agonist with IC50s of 4 nM, 2 nM, and 1 nM for PACAP type I receptor, PACAP type II receptor VIP1, and PACAP type II receptor VIP2 respectively. |
| CSN11051 | Forskolin | 66575-29-9 | Forskolin is a ubiquitous activator of eukaryotic adenylyl cyclase (AC) in a wide variety of cell types with binding (IC50=41 nM) to and activation (EC50=0.5 μM) of type I adenylyl cyclase. It is commonly used to raise levels of cAMP in the research of cell physiology. |
| CSN20413 | CB7921220 | 115453-99-1 | CB7921220 is an inhibitor of adenylyl cyclase isoform-1 (AC1) and isoform-6 (AC6). |
| CSN22739 | cAMPS-Rp, Triethylammonium Salt | 151837-09-1 | cAMPS-Rp, Triethylammonium Salt acts as a competitive antagonist of cAMP-induced activation of PKA (IC50 = 11 - 16 μM) by interacting with cAMP binding sites on the regulatory subunits. |
| CSN10469 | Bithionol | 97-18-7 | Bithionol is an anti-parasitic drug and can be used to inhibit solid tumor growth in several preclinical cancer models. |
| CSN25537 | Dideoxyadenosine | 4097-22-7 | 2′,3′-Dideoxyadenosine is a nucleoside analog of deoxyadenosine. It inhibits adenylyl cyclase and may play a key role in the inhibition of tumor progression. It is a potent inhibitor of reverse transcriptase enzyme of HIV. |
| CSN27244 | 2′,5′-Dideoxyadenosine | 6698-26-6 | 2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor via binding the P-site with an IC50 of 3 µM . 2',5'-Dideoxyadenosine is a nucleoside analog and exerts a potent antiadrenergic action in heart . |
| CSN19770 | 14-Deoxyandrographolide | 4176-97-0 | 14-Deoxyandrographolide, a natural product isolated and purified from the herbs of Andrographis paniculata (Burm. |
