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| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN21304 | SL910102 | 144756-71-8 | SL910102 is a nonpeptide angiotensin AT1 receptor antagonist. |
| CSN21291 | ML171 | 6631-94-3 | ML171 is a novel and selective NOX1 inhibitor with IC50 value of 0.25 μM for blocking NOX1-dependent ROS generation in a HEK293-NOX1 recombinant cell system. |
| CSN21155 | L-NMMA Acetate | 53308-83-1 | L-NMMA acetate is a nitric oxide synthase inhibitor of all NOS isoforms including NOS1, NOS2, and NOS3. The Ki values for nNOS (rat), eNOS (human), and iNOS (mouse) are approximately 0.18, 0.4, and 6 µM, respectively. |
| CSN21293 | Caldaret | 133804-44-1 | Caldaret is an intracellular Ca2+ handling modulator that acts through reverse mode Na+/Ca2+ exchanger inhibition. |
| CSN21258 | Tecadenoson | 204512-90-3 | Tecadenoson is a selective A1 adenosine receptor agonist. |
| CSN21296 | AGN 192836 | 171102-29-7 | AGN 192836 is a potent and selective α2 adrenergic agonist with EC50s of 8.7, 41 and 6.6 nM for α2A, α2B and α2C receptor, respectively. |
| CSN21247 | (±)-WS75624B | 188048-45-5 | (±)-WS75624B is an endothelin converting enzyme (ECE) inhibitor with an IC50 of 0.03 μg/mL. |
| CSN21324 | Naminidil | 220641-11-2 | Naminidil is a cyanoguanidine KATP opener. |
| CSN21301 | FR183998 | 239440-20-1 | FR183998 free base is a potent Na+/H+-exchange inhibitor, with IC50s of 0.3 nM, 3.1 nM and 6.5 nM by measurement of pHi change in rat lymphocytes, rat and human platelets, respectively. |
| CSN22524 | Trombodipine | 113658-85-8 | Trombodipine is an antithrombotic agent. |
| CSN22330 | RP 54275 | 81364-78-5 | 2-Octadecyl-1H-indole-5-carboxylic acid is a novel hypocholesterolaemic drug. |
| CSN22500 | RP-64477 | 135239-65-5 | RP-64477 is a potent inhibitor of the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT). |
| CSN22112 | Declaben | 111149-90-7 | Lodelaben is a human neutrophil elastase inhibitor with an IC50 and Ki of 0.5 and 1.5 μM, respectively. |
| CSN22113 | Ifetroban | 143443-90-7 | Ifetroban is a long-acting thromboxane A2 receptor antagonist, with antiplatelet activity. |
| CSN22149 | Prolylleucine | 61596-47-2 | Prolylleucine is a dipeptide containing branched-chain amino acids. |
| CSN22110 | Bepridil HCl | 68099-86-5 | Bepridil HCl is a calcium channel blocker, with antianginal activity. |
| CSN22159 | ICI 153110 | 87164-90-7 | ICI 153110 is an orally active phosphodiesterase inhibitor with both vasodilating and inotropic properties which is designed for the treatment of congestive cardiac failure. |
| CSN21356 | S107 HCl | 1357476-46-0 | S107 HCl is a RyR-selective 1,4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels. |
| CSN22181 | OM-189 | 55381-18-5 | OM-189 is a selective synthetic thrombin inhibitor. |
| CSN21359 | SQ-31765 | 138383-07-0 | SQ-31765 is a benzazepine calcium channel blocker. |
| CSN22154 | F 16915 | 92510-91-3 | F 16915 is a docosahexaenoic acid derivative which can prevent heart failure-induced atrial fibrillation. |
| CSN21398 | PKG Drug G1 | 374703-78-3 | PKG Drug G1 targets C42 of PKG Iα. PKG drug G1 can couple to vasodilation and blood pressure lowering by a C42 PKG Iα-independent mechanism. |
| CSN22168 | FKK | 78299-79-3 | FKK is an indazole derivative and also a novel bronchodilator. |
| CSN22205 | TAK-024 | 186971-69-7 | TAK-024 is a platelet inhibitor with IC50s of 31, 79 and 51 nM in human, monkey and guinea pig, respectively. |
| CSN22246 | TA-7552 | 104756-72-1 | TA-7552 is a potent cholesterol-lowering agent. |
| CSN22235 | Almokalant | 123955-10-2 | Almokalant is a class III antiarrhythmic drug, acts as a potassium channel blocker, and inhibits a specific component (Ikr) of the time-dependent delayed rectifier K+ current. |
| CSN22338 | AE-3763 | 291778-77-3 | AE-3763 is a peptide-based human neutrophil elastase inhibitor with an IC50 of 29 nM. |
| CSN22373 | CGRP Antagonist 1 | 1123757-49-2 | CGRP antagonist 1 is a highly potent CGRP receptor antagonist with a Ki and IC50 of 35 and 57 nM, respectively. |
| CSN22398 | ETA Antagonist 1 | 161801-60-1 | ETA antagonist 1 is a ETA selective antagonist with an IC50 of 0.08 μM. |
| CSN22431 | Ingliforib | 186392-65-4 | Ingliforib is a glycogen phosphorylase inhibitor, with IC50s of 52, 352 and 150 nM for liver, muscle and brain glycogen phosphorylase, and has cardioprotective activity. |
| CSN22395 | EPAC 5376753 | 302826-61-5 | EPAC 5376753 is an allosterically inhibitor of Epac which inhibits Epac1 with an IC50 of 4 µM in Swiss 3T3 cells. |
| CSN22511 | Solenopsin | 137038-57-4 | Solenopsin is an ATP-competitive AKT inhibitor with IC50 value of 10 μM . |
| CSN22490 | Pparδ Agonist 1 | 1902161-12-9 | Pparδ agonist 1 is a PPAR-δ agonist, with an EC50 of 5.06 nM, used in the research of PPAR-delta related diseases, such as mitochondrial diseases, muscular diseases, vascular diseases, demyelinating diseases and metabolic diseases. |
| CSN22444 | L-765314 | 189349-50-6 | L-765314 is a potent and selective α1b adrenergic receptor antagonist with Kis of 5.4±0.6 nM and 2.0±0.66 nM for rat and human α1b adrenergic receptor, respectively. |
| CSN22536 | ZD-0892 | 171964-73-1 | ZD-0892 is a selective and potent inhibitor of a neutrophil elastase with Kis of 6.7 and 200 nM for human neutrophil elastase and porcine pancreatic elastase, respectively. |
| CSN22140 | Y-9738 | 59399-41-6 | Y-9738 is a hypolipidemic agent. |
