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Cardiovascular Disease

货号 产品名 CAS号 信息
CSN10870 N-(2-Butyl-3-(4-(3-(dibutylamino)propoxy)benzoyl)benzofuran-5-yl)methanesulfonamide hydrochloride 141625-93-6 Dronedarone HCl is a multichannel blocker targeting potassium channel, sodium channel and calcium channel, used as an antiarrhythmic drug for treatment of atrial fibrillation (AF).
CSN10893 Efonidipine HCl monoethanolate 111011-76-8 Efonidipine HCl monoethanolate is a dual T-type and L-type calcium channel blocker (CCB).
CSN10907 (S)-1-((S)-2-(((S)-1-Carboxy-3-phenylpropyl)amino)propanoyl)pyrrolidine-2-carboxylic acid dihydrate 84680-54-6 Enalaprilat is the first dicarboxylate-containing ACE inhibitor with IC50 of 1.94 nM, which is the active metabolite of enalapril.
CSN10923 Eprosartan mesylate 144143-96-4 Eprosartan Mesylate is a reversible and competitive angiotensin II receptor inhibitor.
CSN10925 Eptifibatide 188627-80-7 Eptifibatide is a specific inhibitor of fibrinogen working by binding to the platelet membrane integrin αIIbβ3 receptor and preventing platelet aggregation.
CSN10951 5-Amino-[3,4'-bipyridin]-6(1H)-one 60719-84-8 Amrinone is a type 3 pyridine phosphodiesterase inhibitor used in the treatment of congestive heart failure.
CSN52424 6-Chloro-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol methanesulfonate 67227-57-0
CSN11008 Sodium ferulic 24276-84-4 Sodium ferulate is the sodium salt of ferulic acid which is used for the treatment of cardiovascular disease.
CSN11077 2,2',2''-(Benzene-1,2,3-triyltris(oxy))tris(N,N,N-triethylethanaminium) iodide 65-29-2 Gallamine triethiodide is a competitive cholinergic receptor blocker with an IC50 of 68.0 ± 8.4 μM, used as a non-depolarising muscle relaxant.
CSN11151 Oglufanide 38101-59-6 Oglufanide is inhibitor of vascular endothelial growth factor (VEGF) that suppresses angiogenesis.
CSN11239 Ivabradine HCl 148849-67-6 Ivabradine HCl is the first selective sinus node I(f) channel, used for the symptomatic management of stable heart-related chest pain and heart failure not fully managed by β blockers.
CSN11285 Lercanidipine HCl 132866-11-6 Lercanidipine HCl is a L-type calcium channel blocker, used in the treatment of hypertension.
CSN11300 Lidocaine HCl hydrate 6108-05-0 Lidocaine HCl is antiarrhythmic agent and used as a local anesthetic.
CSN11313 Lisinopril 76547-98-3 Lisinopril is angiotensin-converting enzyme inhibitor that blocks the formation of angiotensin I with an IC50 value of 1.2 nM (ovine) and displays ID50 values of 2.3 and 6.5 µg/kg in rat and canine, respectively. It is used in treatment of hypertension, congestive heart failure, and heart attacks.
CSN11333 Losartan 114798-26-4 Losartan is a compeitive AT1 receptor inhibitor with IC50 value of 20 nM.
CSN11335 (S)-(1S,3R,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2-methylbutanoate 75330-75-5 Lovastatin is a HMG-CoA reductase used to treat high blood cholesterol and reduce the risk of cardiovascular disease, a naturally occuring fungal metabolite.
CSN11439 Mibefradil 2HCl 116666-63-8 Mibefradil 2HCl is calcium channel blocker with moderate selectivity for T-type Ca2+ channels displaying
CSN11450 2,6-Diamino-4-(piperidin-1-yl)pyrimidine 1-oxide 38304-91-5 Minoxidil is an antihypertensive vasodilator medication.
CSN11125 Guanabenz Acetate 23256-50-0 Guanabenz acetate is a centrally-acting α-2 adrenergic receptor agonist that is used as an antihypertensive drug to treat hypertension.
CSN10861 Doxazosin 74191-85-8 Doxazosin is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors.
CSN11266 Lanatoside C 17575-22-3 Lanatoside C is a cardiac glycoside, can be used in the treatment of congestive heart failure and cardiac arrhythmia.Lanatoside C has an IC50 of 0.19 μM for dengue virus infection in HuH-7 cells.
CSN11163 Hydralazine HCl 304-20-1 Hydralazine HCl is a direct-acting vasodilator that is used as an antihypertensive agent.
CSN11184 Ibutilide fumarate 122647-32-9 Ibutilide Fumarate is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm.
CSN10922 Eprosartan 133040-01-4 Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure.
CSN11235 3-Isopropyl 5-methyl 4-(benzo[c][1,2,5]oxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 75695-93-1 Isradipine is a potent L-type calcium channel selective blocker with an IC50 of 34±8 μM.
CSN11164 Ethyl 2-(6-(ethyl(2-hydroxypropyl)amino)pyridazin-3-yl)hydrazine-1-carboxylate 64241-34-5 Cadralazine is an antihypertensive of the hydrazinophthalazine chemical class.
CSN10855 DOPEXAMINE 86197-47-9 Dopexamine is a synthetic analogue of dopamine that is administered intravenously in hospitals to reduce exacerbations of heart failure and to treat heart failure following cardiac surgery.
CSN11071 Gabexate Mesylate 56974-61-9 Gabexate mesylate could inhibit trypsin, plasmin, plasma kallikrein and thrombin with IC50s of 9.4 μM, 30 μM, 41 μM and 110 μM. It has certain anticoagulant effect.
CSN11218 Isbogrel 89667-40-3 Isbogrel, a ω-pyridylalkenoic acid derivative, is a thromboxane A2 synthetase inhibitor that also shows thromboxane A2 antagonism.
CSN11258 L-165041 79558-09-1 L-165041 is a cell permeable PPARδ agonist which induces adipocyte differentiation in NIH-PPARδ cells.
CSN11018 Flecainide acetate 54143-56-5 Flecainide Acetate is a class 1C antiarrhythmic drug especially used for the management of supraventricular arrhythmia and works by blocking the Nav1.5 sodium channel in the heart, causing prolongation of the cardiac action potential.
CSN11438 Mibefradil 116644-53-2 Mibefradil is calcium channel blocker with moderate selectivity for T-type Ca2+ channels displaying
CSN11284 Lercanidipine 100427-26-7 Lercanidipine is a calcium channel blocker of the dihydropyridine class.
CSN10869 N-(2-Butyl-3-(4-(3-(dibutylamino)propoxy)benzoyl)benzofuran-5-yl)methanesulfonamide 141626-36-0 Dronedarone is a therapeutic agent with a structural resemblance to amiodarone and a better side effect profile and it is a multichannel blocker with antiadrenergic properties and has been evaluated in both rate and rhythm control strategies in the management of AF.
CSN11314 Lisinopril Dihydrate 83915-83-7 Lisinopril is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks.
CSN10940 Ethamsylate 2624-44-4 Ethamsylate acts as a haemostatic drug by increasing capillary endothelial resistance and promoting platelet adhesion.
CSN11017 Flecainide 54143-55-4 Flecainide acetate, a class Ic antiarrhythmic agent, can block the Nav1.5 sodium channel and inhibit ryanodine receptor 2 (RyR2). It is used to prevent and treat tachyarrhythmias.
CSN11261 Lacidipine 103890-78-4 Lacidipine is a L-type calcium channel blocker, used for treating high blood pressure.
CSN11358 Manidipine 89226-50-6 Manidipine is a calcium channel blocker that is used clinically as an antihypertensive.
CSN11359 Manidipine Dihydrochlorid 89226-75-5 Manidipine 2HCl is a L/T-type calcium channel blocker for Ca2+ current with IC50 of 2.6 nM.
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