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Casein Kinase

Casein Kinase

货号 产品名 CAS号 信息
CSN15858 TTP 22 329907-28-0 TTP 22 is a high affinity, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50/Ki of 0.1 μM/40 nM, showing selectivity for CK2 over JNK3, ROCK1, and MET (IC50> 10 μM).
CSN25710 TMCB 905105-89-7 TMCB is a dual-kinase inhibitor of both casein kinase 2 (CK2) and extracellular-signal-regulated kinase 8 (ERK8) with IC50s of 0.50 μM.
CSN19438 TBB 17374-26-4 TBB is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2)with IC50s of 0.9 and 1.6 μM for rat liver and human recombinant CK2 respectively).
CSN26213 PI-828 942289-87-4 PI-828 is a dual PI3K and casein kinase 2 (CK2) inhibitor with IC50s of 173 nM, 149 nM, and 1127 nM for p110α, CK2, and CK2α2 in lipid kinase assay, respectively.
CSN16518 PF-670462 950912-80-8 PF-670462 is a potent and selective inhibitor of CK1ε with IC50 of 7.7 ± 2.2 nM.
CSN22941 PF-4800567 1188296-52-7 PF-4800567 is an inhibitor of casein kinase 1ε (CK1ε) with IC50 of 32 nM.
CSN24190 NCC007 2342583-66-6 NCC007 is a dual CK1α and CK1δ inhibitor with IC50 value of 1.8 and 3.6μM, respectively.
CSN16329 LH846 639052-78-1 LH846 is a selective inhibitor of casein kinase (CK) 1δ with IC50 of 290 nM, 1.3 μM and 2.5 μM for CK1δ, ε and α, displays no inhibitory activity at CK2.
CSN18054 IC261 186611-52-9 IC261 is an ATP-competitive inhibitor of CK1 with IC50s about 1 μM for CK1δ and CK1ε, 16 μM for CK1α.
CSN19160 H 89 2HCl   130964-39-5 H 89 2HCl is a potent and selective inhibitor of cyclic AMP-dependent protein kinase (protein kinase A) with IC50 of 48 nM. It also shows weak inhibition on PKG, PKC, CK1, CK2 and others kinases.
CSN63435 GO289 694522-87-7 GO289 is a potent and selective CK2 inhibitor.
CSN26540 CK2/PIM1-IN-1 292640-28-9 for CK2 and PIM1, respectively. CK2/PIM1-IN-1 is developed for the research of proliferative disorders such as cancer, as well as other kinase-associated conditions including inflammation, pain, vascular disorders, pathogenic infections and certain immunological disorders[1].
CSN18468 Emodin 518-82-1 Emodin shows antiproliferative effects in cancer cells that are regulated by different signaling pathways, it is a naturally occurring anthraquinone present in the roots and barks of numerous plants.
CSN10902 Ellagic Acid 476-66-4 Ellagic acid is a potent and cell permeable casein kinase 2 (CK2) inhibitor with Ki of 20 nM, acts as a potent antioxidant and anti-mutagenic.
CSN16246 DMAT 749234-11-5 DMAT is a potent and specific CK2 inhibitor with an IC50 value of 130 nM.
CSN13638 D4476 301836-43-1 D4476 is a potent, selective, and cell-permeant CK1 (casein kinase 1) inhibitor with IC50 of 200 nM and 300 nM in a cell-free assay for CK1 from Schizosaccharomyces pombe and CK1δ, respectively. Also acts as an ALK5 inhibitor with IC50 of 500 nM.
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