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Casein Kinase
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN15858 | TTP 22 | 329907-28-0 | TTP 22 is a high affinity, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50/Ki of 0.1 μM/40 nM, showing selectivity for CK2 over JNK3, ROCK1, and MET (IC50> 10 μM). |
| CSN25710 | TMCB | 905105-89-7 | TMCB is a dual-kinase inhibitor of both casein kinase 2 (CK2) and extracellular-signal-regulated kinase 8 (ERK8) with IC50s of 0.50 μM. |
| CSN19438 | TBB | 17374-26-4 | TBB is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2)with IC50s of 0.9 and 1.6 μM for rat liver and human recombinant CK2 respectively). |
| CSN16518 | PF-670462 | 950912-80-8 | PF-670462 is a potent and selective inhibitor of CK1ε with IC50 of 7.7 ± 2.2 nM. |
| CSN22941 | PF-4800567 | 1188296-52-7 | PF-4800567 is an inhibitor of casein kinase 1ε (CK1ε) with IC50 of 32 nM. |
| CSN24190 | NCC007 | 2342583-66-6 | NCC007 is a dual CK1α and CK1δ inhibitor with IC50 value of 1.8 and 3.6μM, respectively. |
| CSN16329 | LH846 | 639052-78-1 | LH846 is a selective inhibitor of casein kinase (CK) 1δ with IC50 of 290 nM, 1.3 μM and 2.5 μM for CK1δ, ε and α, displays no inhibitory activity at CK2. |
| CSN18054 | IC261 | 186611-52-9 | IC261 is an ATP-competitive inhibitor of CK1 with IC50s about 1 μM for CK1δ and CK1ε, 16 μM for CK1α. |
| CSN18468 | Emodin | 518-82-1 | Emodin shows antiproliferative effects in cancer cells that are regulated by different signaling pathways, it is a naturally occurring anthraquinone present in the roots and barks of numerous plants. |
| CSN10902 | Ellagic Acid | 476-66-4 | Ellagic acid is a potent and cell permeable casein kinase 2 (CK2) inhibitor with Ki of 20 nM, acts as a potent antioxidant and anti-mutagenic. |
| CSN16246 | DMAT | 749234-11-5 | DMAT is a potent and specific CK2 inhibitor with an IC50 value of 130 nM. |
| CSN13638 | D4476 | 301836-43-1 | D4476 is a potent, selective, and cell-permeant CK1 (casein kinase 1) inhibitor with IC50 of 200 nM and 300 nM in a cell-free assay for CK1 from Schizosaccharomyces pombe and CK1δ, respectively. Also acts as an ALK5 inhibitor with IC50 of 500 nM. |
