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Chalcones

Chalcones

货号 产品名 CAS号 信息
CSN12218 Xanthohumol 6754-58-1 Xanthohumol, a prenylated chalcone from hop, is an inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2 and shows chemopreventive effects.
CSN14574 Xanthohumol(Random Configuration) 569-83-5 Xanthohumol, a natural product isolated and purified from the herbs of Humulus lupulus and a potent chemotherapeutic candidate for cervical cancer, inhibits the development of obese patients as well as the progression of non-alcoholic fatty liver disease, and displays anti-hepatitis C virus activity in a cell culture system and may be potentially used as an alternative or complementary treatment against the hepatitis C virus.
CSN14763 Xanthohumol D 274675-25-1 Xanthohumol D, a natural product isolated and purified from the herbs of Humulus lupulus, is a potent inhibitor of quinone reductase-2 (QR-2) with IC50 of 110μM.
CSN14204 Trilobatin 4192-90-9 Trilobatin, a natural product isolated and purified from the herbs of Lithocarpus pachyphyllus with anti-oxidant effect, potentially inhibits the LPS-induced inflammatory response by suppressing the NF-κB signaling pathway and is a potential effective α-glucosidase inhibitor for management of postprandial hyperglycemia with less side effect.
CSN14764 Trilobatin 2''-acetate 647853-82-5 Trilobatin 2''-acetate is a natural product isolated and purified from the herbs of Lithocarpus pachyphyllus.
CSN13694 Sappanchalcone 94344-54-4 Sappanchalcone, a natural product isolated and purified from the heartwood of Caesalpinia sappan L., suppresses oral cancer cell growth and induces apoptosis through the activation of p53-dependent mitochondrial, p38, ERK, JNK, and NF-κB signaling, could potentially used to treat periodontal, pulpal , periapical inflammatory lesion and oral cancer.
CSN18727 Pinostrobin chalcone 18956-15-5 Pinostrobin chalcone, a natural product isolated and purified from the heartwoods of Lindera umbellata. with phytoalexin and anti-inflammatory activities, has very remarkable cytotoxic activity against the human cancer cells, such as KB, MCF7 and Caski cells (IC50 values of 6.2, 7.3 and 7.7 µg/mL, respectively).
CSN14095 Pinocembrin chalcone 4197-97-1 Pinocembrin chalcone is an antibacterial compound from Helichrysum trilineatum.
CSN13514 Phlorizin Dihydrate 7061-54-3 Phlorizin significantly inhibits oxidative DNA damage, it is a natural product isolated and purified from the herbs of Prunus armeniaca L..
CSN11698 Phlorizin 60-81-1 Phlorizin is an inhibitor of hSGLT1 (Ki=300 nM) and hSGLT2 (Ki= 39 nM). It can be found in a number of fruit trees.
CSN11697 Phloretin 60-82-2 Phloretin, a dihydrochalcone flavonoid, can inhibit the active transport of glucose into cells by SGLT1 and SGLT2. It is mainly found in fruit and roots of apple tree.
CSN18726 Pashanone 42438-78-8 Pashanone possesses moderate antifungal activity.
CSN11538 Neohesperidin dihydrochalcone 20702-77-6 Neohesperidin Dihydrochalcone is an artificial sweetener derived from citrus.
CSN13476 Morachalcone A 76472-88-3 Morachalcone A, a natural product isolated and purified from the roots of Morus alba with antioxidant and cytotoxic activities, exhibits potent inhibitory activity on nitric oxide production in RAW264.7 LPS-activated mouse macrophage cells with IC50 values of 16.4 μM.
CSN13306 Methyllinderone 3984-73-4 Methyllinderone is a natural product isolated and purified from the roots of Lindera aggregata(Sims) Kosterm, showing moderate to weak antifungal activities against various pathogenic fungi, and selectively inhibits the growth of H-ras-transformed rat-2 cell lines with a GI50 value of 0.3 mM.
CSN14046 (Z)-2-((E)-1-Hydroxy-3-phenylallylidene)-4-methoxycyclopent-4-ene-1,3-dione 19956-53-7 Lucidone is a natural product isolated and purified from the root of Lindera strychnifolia with antioxidant, anti-inflammatory and anti-melanogenic activities.
CSN13253 Linderone 1782-79-2 Linderone is a natural product isolated and purified from the roots of Lindera aggregata (Sims) Kosterm.
CSN16424 Licochalcone A   58749-22-7 Licochalcone A, an estrogenic flavanoid, can be an inhibitor of p-glycoprotein and has anti-inflammatory actions.
CSN19894 Isoliquiritin 5041-81-6 Isoliquiritin is a natural product isolated and purified from the root of Glycyrrhiza uralensis Fisch. With antipyretic, antiinflammatroy, antioxidant, estrogenic, anticancer, antifungal and antidepressant-like effects.
CSN16506 Isoliquiritigenin 961-29-5 Isoliquiritigenin is a licorice chalconoid, a type of natural phenols, and a sirtuin-activating compound.
CSN14766 Isodorsmanin A 118266-99-2 Isodorsmanin A is a natural product isolated and purified from the herbs of Psoralea corylifolia L..
CSN14205 4-Hydroxylonchocarpin 56083-03-5 Isobavachromene is a natural product isolated and purified from the seeds of Psoralea corylifolia L..
CSN13965 Isobavachalcone 20784-50-3 Isobavachalcone can induce apoptosis in neuroblastoma, is a chalcone isolated and purified from Angelica keiskei and the fruits of Psoralea corylifolia L.
CSN11176 Hydroxysafflor yellow A 78281-02-4 Hydroxysafflor yellow A is a flavonoid derived and isolated from traditional Chinese medicine Carthamus tinctorius L., possessing anti-tumor activity.
CSN19782 1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one 56798-34-6 Flavokawain C is a naturally occurring chalcone that has been isolated from several medicinal plants.
CSN18812 Flavokawain A 3420-72-2 Flavokawain A, a natural product isolated and purified from the roots of Piper methysticum with anti-tumor and anti-inflammatory activities, can significantly reduce the expression of CDK1-inhibitory kinases, Myt1 and Wee1, and cause cyclin B1 protein accumulation leading to CDK1 activation in T24 cells.
CSN19432 Echinatin 34221-41-5 Echinatin, a natural product isolated and purified from the root of Glycyrrhiza glabra L.
CSN14206 (E)-1-(5-Hydroxy-2,2-dimethylchroman-6-yl)-3-(4-hydroxyphenyl)prop-2-en-1-one 162229-27-8 Dorsmanin A is a natural product isolated and purified from the herbs of Psoralea corylifolia.
CSN19898 (E)-Cardamonin 19309-14-9 Cardamonin can supress numerous signaling pathways including TNF-α, COX-2, Wnt/β-catenin and NF-κB, suppresses melanogenesis by inhibition of Wnt/β-catenin signaling, and possesses anti-inflammatory activity via suppression of NF-kB nuclear translocation and Ik-Ba phosphorylation. It is a natural product isolated and purified from the seeds of Alpinia katsumadai Hayata.
CSN10516 Butein 487-52-5 Butein, a plant polyphenol isolated from Rhus verniciflua, is able to inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, also inhibits EGFR.
CSN14207 Asebotin 11075-15-3 Asebotin is a dihydrochalcone glucoside isolated and purified from Guibourtia tessmannii.
CSN12912 Asebogenin 520-42-3 Asebogenin is a natural product isolated and purified from Lippia salviaefolia.
CSN14765 4-O-Methylhelichrysetin 56121-44-9 4-O-Methylhelichrysetin is a natural product isolated and purified from the herbs of Cephalotaxus sinensis.
CSN15311 3'-Methylflavokawin 1044743-35-2 3'-Methylflavokawin is a natural product isolated and purified from the herbs of Humulus lupulus showing cytotoxicity against HeLa cells, the IC 50 value comparable to xanthohumol (8.2-19.2 mM).
CSN15312 3'-Methyl-4-O-Methylhelichrysetin 109471-13-8 3'-Methyl-4-O-methylhelichrysetin is a natural product isolated and purified from the barks of Cephalotaxus sinensis.
CSN13267 2-Hydroxy-3,4,5,6-Tetramethoxychalcone 219298-74-5 2-Hydroxy-3,4,5,6-tetramethoxychalcone is a natural product isolated and purified from the herbs of Fissistigma bracteolatum.
CSN13919 2'-O-Methylisoliquiritigenin 51828-10-5 2'-O-Methylisoliquiritigenin is a natural product isolated and purified from the roots of Glycyrrhiza glabra L..
CSN13227 2',4'-Dihydroxy-3',6'-Dimethoxychalcone 54299-50-2 2',4'-Dihydroxy-3',6'-dimethoxychalcone is a natural product isolated and purified from the herbs of Chloranthus spicatus with antiproliferative, anti-inflammatory and anti-cholinesterase activities.
CSN13191 2',4'-Dihydroxy-2,3',6'-trimethoxychalcone 100079-39-8 2',4'-Dihydroxy-2,3',6'-trimethoxychalcone is a natural product isolated and purified from the herb of Scutellaria discolor.
CSC13514 Phlorizin Dihydrate 7061-54-3
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