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Chk

Chk

货号 产品名 CAS号 信息
CSN17165 PF-477736 952021-60-2 PF-477736 is a selective, potent and ATP-competitive Chk1 inhibitor with Ki of 0.49 nM and also inhibits VEGFR2, Aurora-A, FGFR3, Flt3, Fms (CSF1R), Ret and Yes and shows ~100-fold selectivity for Chk1 than Chk2.
CSN23009 NSC 109555 Ditosylate 66748-43-4 NSC 109555 Ditosylate is a selective, reversible, ATP-competitive Chk2 inhibitor with IC50 of 0.2 μM.
CSN17600 LY2606368 2HCl 1234015-54-3 LY2606368 (Prexasertib) is a selective Chk1 inhibitor with IC50 value <1nM, modest to Chk2 and Rsk with IC50 values of 8nM and <10nM.
CSN16323 BML-277 516480-79-8 BML-277 is a selective Chk2 (checkpoint kinase 2) inhibitor with IC50 of 15 nM.
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