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货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN27218 | MN58b | 203192-01-2 | MN58b is a CHKα inhibitor that inhibits phosphocholine synthesis and reduced cell growth through induction of apoptosis. |
CSN25346 | EB-3D | 1839150-63-8 | EB-3D is a novel potent and selective choline kinase ChoKα inhibitor with an IC50 of 1 μM. EB-3D induces deregulation of the AMPK-mTOR pathway and apoptosis in leukemia T-cells and induces senescence in breast cancer cell lines through the activation of the metabolic sensor AMPK and the subsequent dephosphorylation of mTORC1 downstream targets. |
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