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Coumarins
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN13084 | 7-Hydroxy-2H-chromen-2-one | 93-35-6 | Umbelliferone, a natural product isolated and purified from the herbs of Ruta graveolens L., exhibits significant anticancer effects via the induction of apoptosis, cell cycle arrest and DNA fragmentation in HepG2 cancer cells. |
| CSN13943 | Suberosin | 581-31-7 | Suberosin, a natural product isolated and purified from the roots of Angelica pubescens, inhibits PHA-induced PBMC proliferation, at least in part, through reduction of [Ca2+]i, ERK, NF-AT, and NF-kappaB activation, and early gene expression in PBMC including cyclins and cytokines, and arrest of cell cycle progression in the cells. |
| CSN13982 | sphondin | 483-66-9 | Sphondin, a natural product isolated and purified from the fruits of Heracleum sibiricum L., possesses an inhibitory effect on IL-1beta-induced increase in the level of COX-2 protein and PGE(2) release in A549 cells. |
| CSN13328 | Scopoletin acetate | 56795-51-8 | Scopoletin acetate is a natural product isolated and purified from the herbs of Atropa belladonna L.. |
| CSN16631 | 6,7-Dimethoxy-2H-chromen-2-one | 120-08-1 | Scoparone, a natural product isolated and purified from the herbs of Artemisia scoparia, with antifungal, antianginal, antioxidant, immunosuppression and vasorelaxation effects, protects against carbon tetrachloride-induced liver injury, is a very efficient inhibitor of ultraviolet radiation -induced lipid peroxidation and damage, and a phytoalexin associated with resistance of citrus to Phytophthora citrophthora. |
| CSN14016 | Samidin | 477-33-8 | Samidin, a natural product isolated and purified from the fruits of Ammi visnaga., has anti-inflammatory properties through suppression of NF-κB and AP-1-mediated-genes in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. |
| CSN16251 | psoralidin | 18642-23-4 | Psoralidin, a natural furanocoumarin, is isolated from Psoralea corylifolia L. with anticancer and chemopreventive properties, inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation. |
| CSN16448 | 7H-Furo[3,2-g]chromen-7-one | 66-97-7 | Psoralen, an ingredient from Fructus Psoraleae, intercalates with DNA, inhibiting DNA synthesis and cell division and showing anticancer activity. |
| CSN16138 | Pimpinellin | 131-12-4 | Pimpinellin, a natural product isolated and purified from the fruits of Psoralea corylifolia L. |
| CSN14011 | Phebalosin | 6545-99-9 | Phebalosin, a natural product isolated and purified from the herbs of Murraya exotica L., displays EC(50) of 14.1 mg/mL against axenic amastigote forms of Leishmania panamensis. and cytotoxicity (IC(50)) at concentrations of 20.7 mg/mL on human promonocytic U-937 cells. |
| CSN19790 | Oxypeucedanin | 737-52-0 | Oxypeucedanin is a natural product with anti-tumor activity, isolated and purified from the root of Angelica dahurica.It is a kind of open-channel blocker of the hKv1.5 channel. |
| CSN14017 | Oxypeucedanin Hydrate | 133164-11-1 | Oxypeucedanin is a chemical constituent from polarity part in roots of Angelica dahurica var. formosana cv. Chuanbaizhi. |
| CSN14020 | Osthol hydrate | 69219-24-5 | Osthol is a natural product isolated and purified from the fructus of Cnidium monnieri (L.) Cusson. |
| CSN13525 | Notopterol | 88206-46-6 | Notopterol induces apoptosis and inhibits cell cycle-specific, it's a natural product isolated and purified from the roots of Notopterygium incisum. |
| CSN14225 | Neoglycyrol | 23013-84-5 | Neoglycyrol is a natural product isolated and purified from the roots of Glycyrrhiza uralensis Fisch with some cardioprotective effects . |
| CSN14004 | Meranzin hydrate | 5875-49-0 | Meranzin, a natural product isolated and purified from the roots of Angelica biserrata, produces a rapid effect mediated by AMPA receptors and involving BDNF modulation through the ERK1/2 pathway. Meranzin can also induce similar effect to Fructus Aurantii on intestinal motility and it was, at least in part, mediated by stimulation of H1 histamine receptors, and exhibits antidepressive and prokinetic-like effects through the regulation of the common mediator, the alpha 2-adrenoceptor , and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors. |
| CSN14012 | Meranzin | 23971-42-8 | Meranzin, a natural product isolated and purified from the peel of Citrus maxima, can induce similar effect to Fructus Aurantii on intestinal motility and it was, at least in part, mediated by stimulation of H1 histamine receptors. |
| CSN13967 | Mellein | 480-33-1 | Mellein is a natural product isolated and purified from the herbs of Goniothalamus griffithii. |
| CSN10152 | Isoscopoletin | 776-86-3 | Isoscopoletin is a natural product isolated and purified from the herbs of Paederia scandens (Lour.) Merr. |
| CSN16367 | Isopimpinellin | 482-27-9 | Isopimpinellin is an inhibitor of 7,12-Dimethylbenz(a)anthracene which is initiator of skin tumors or breast cancers, is isolated from the roots of Pimpinella saxifraga., reported to use in the management of breast cancers. |
| CSN10961 | Isofraxidin | 486-21-5 | Isofraxidin, a natural product isolated and purified from the herbs of Sarcandra glabra (Thunb.) Nakai, possesses significant analgesic and anti-inflammatory activities that may be mediated through the regulation of pro-inflammatory cytokines, TNF-α and the phosphorylation of p38 and ERK1/2. |
| CSN16604 | Isobergapten | 482-48-4 | Isobergapten, a natural product isolated and purified from the fruits of Citrus medica L., shows anti-proliferative activity and causes G2/M arrest at concentrations of 0.05-15.0 μM, and is the principal constituents responsible for the antimycobacterial activity of the roots of Heracleum maximum. |
| CSN13966 | Heraclenol | 31575-93-6 | Heraclenol, a natural product isolated and purified from the herbs of Heracleum repula Franch, can inhibit the proliferation of melanoma cells and cell cycle. |
| CSN19923 | Fraxinol | 486-28-2 | Fraxinol is a natural product isolated and purified from the bark of Fraxinus chinensis Roxb. |
| CSN11055 | Fraxin | 524-30-1 | Fraxin protects HUVECs from oxidative stress, enhances urate excretion partly by inhibiting mURAT1 or mGLUT9 in kidney of hyperuricemic mice. It is a natural product isolated and purified from the bark of Fraxinus brngeana DC.. |
| CSN11054 | Fraxidin | 525-21-3 | Fraxidin is a natural product isolated and purified from the herbs of Sarcandra glabra. |
| CSN16387 | 7-Hydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chromen-2-one | 531-75-9 | Esculin is a glucoside isolated and purified from the peel of Aesculus hippocastanum L., possessing antiflogistic, cytostatic, and antimutagenic properties, and is used for the treatment of various peripheral vascular disorders and in a microbiology laboratory to aid in the identification of bacterial species (especially Enterococci and Listeria). |
| CSN10746 | Daphnoretin | 2034-69-7 | Daphnoretin, a natural product isolated and purified from the roots of Wikstroemia indica (Linn.) C. A. Mey., has strong antiviral activity, mainly on the later phase of the replication cycle. Daphnoretin also has anticancer effects on leukemia, osteosarcoma and uterine cervix cancer cells, might through promoting apoptosis in a mitochondria-mediated way. |
| CSN12343 | Coumestrol | 479-13-0 | Coumestrol, a natural product isolated and purified from the herbs of Erythrina arborescens, exhibits activities against cancers, neurological disorders, and autoimmune diseases. It suppresses proliferation of ES2 cells with an IC50 of 50 μM. |
| CSN10701 | 2H-Chromen-2-one | 91-64-5 | Coumarin is a secondary phytochemical isolated and purified from the herbs of Melilotus officinalis with hepatotoxic and carcinogenic properties. |
| CSN10014 | Citropten | 487-06-9 | Citropten, a natural product isolated and purified from the peel of Citrus medica L., has interactions with human malignant melanoma A-2058 cells which are exposed to them. |
| CSN13447 | Chloculol | 131652-35-2 | Chloculol is a natural product. |
| CSN19299 | 2H-Furo[2,3-h]chromen-2-one | 523-50-2 | Angelicin, a furocoumarin naturally occurring tricyclic aromatic compound, structurally related to psoralens, is reported to have anti-cancer, antiviral, anti-inflammatory activity. |
| CSN13219 | 8-Geranyloxy-5,7-dimethoxycoumarin | 1228175-65-2 | 8-Geranyloxy-5,7-dimethoxycoumarin is a natural product isolated and purified from the herbs of Toddalia asiatica with antidiabetic and antioxidant effect. |
| CSN10943 | Herniarin | 531-59-9 | 7-Methoxycoumarin, a natural product isolated and purified from the herbs of Citrus reticulata cv. Chachiensis, has potent antioxidant effect, strong hepatoprotective activity, and weak estrogenic activity. |
| CSN13043 | 7-Hydroxy-6-methoxy-3-prenylcoumarin | 299159-90-3 | 7-Hydroxy-6-methoxy-3-prenylcoumarin is a natural product isolated and purified from the herbs of Coriaria nepalensis. |
| CSN13397 | 7-Hydroxy-3-prenylcoumarin | 86654-26-4 | 7-Hydroxy-3-prenylcoumarin is a natural product isolated and purified from the herbs of Coriaria nepalensis. |
| CSN13282 | 7-O-Geranylscopoletin | 28587-43-1 | 7-Geranyloxy-6-methoxycoumarin is a natural product isolated and purified from the herbs of Murraya tetramera Huang, showing significant cytotoxicity against three cell lines (A549, SMMC-7721 and BALL-1). |
| CSN10955 | 7-Amino-4-methylcoumarin | 26093-31-2 | 7-Amino-4-methylcoumarin is a natural product isolated and purified from an endophytic Xylaria fungal species and exhibited strong antibacterial and antifungal activities in vitro against Aspergillus, Candida, Escherichia, Staphylococcus, Salmonella and Vibrio species, among others. It is also a reagent employed in the preparation of fluorogenic AMC-based substrates for the detection of proteolytic enzyme activity. AMC has been utilized as a fluorescent probe to analyze glycoproteins' monosaccharides and N-linked oligosaccharides via chromatography and has been used as a laser dye. |
| CSN13341 | 5,7,8-Trimethoxycoumarin | 60796-65-8 | 5,7,8-Trimethoxycoumarin is a natural product isolated and purified from the herbs of Viola yedonensis Makino. |
| CSN13327 | 5,6,7,8-Tetramethoxycoumarin | 56317-15-8 | 5,6,7,8-Tetramethoxycoumarin is a natural product isolated and purified from the herbs of Croton laevigatus. |
| CSN13076 | 4-Methylumbelliferone | 90-33-5 | 4-Methylumbelliferone, a natural product isolated and purified from the herbs of Ruta graveolens L., is a hyaluronic acid (HA) synthesis inhibitor with an IC50 of 0.4 mM. |
| CSN13450 | 2-(1-Hydroxy-1-Methylethyl)-4-Methoxy-7H-Furo[3,2-G][1]benzopyran-7-One | 54087-32-0 | 2-(1-Hydroxy-1-methylethyl)-4-methoxy-7H-furo[3,2-g][1]benzopyran-7-one is a natural product isolated and purified from the fruits of Evodia lepta. |
| CSN13223 | Yuehgesin C | 125072-68-6 | (S)-Yuehgesin C is a natural product isolated and purified from the herbs of Murraya paniculata. |
| CSN14047 | (-)-Anomalin | 4970-26-7 | (-)-Praeruptorin B is a natural product isolated and purified from Peucedani Radix. |
| CSN14018 | (-)-Heraclenol | 139079-42-8 | (-)-Heraclenol is a natural product isolated and purified from the roots of Angelica dahurica var. formosana cv. Chuanbaizhi. |
| CSN13520 | Praeruptorin A | 73069-27-9 | (+)-Praeruptorin A is a natural product isolated and purified from the roots of Peucedanum praeruptorum Dunn., which exerted distinct relaxant effects on isolated rat aorta rings, which might be mainly attributed to nitric oxide synthesis catalyzed by endothelial nitric oxide synthase. |
| CSN13983 | (+)-Mellein | 62623-84-1 | (+)-Mellein is a natural product isolated and purified from the herbs of Goniothalamus griffithii. |
