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货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN21883 | Urocortin, human | 176591-49-4 | Urocortin, human,is a selective agonist of endogenous CRF2 receptor, with Kis of 0.3, and 0.5 nM for rCRF2α and mCRF2β, respectively. |
CSN11823 | R121919 | 195055-03-9 | R121919 is a potent small-molecule CRF1 receptor antagonist with a Ki of 2 to 5 nM for the CRF1 receptor and over 1000-fold weaker activity at the CRF2 receptor, CRF-binding protein, or 70 other receptor types. |
CSN24468 | Pexacerfont | 459856-18-9 | Pexacerfont is a potent and selective antagonist with IC50 value of 6.1nM. |
CSN17561 | NVS-CRF38 | 1207258-55-6 | NVS-CRF38 is a corticotropin-releasing factor receptor 1 (CRF1) antagonist with low water solubility. |
CSN21288 | Verucerfont | 885220-61-1 | GSK561679 is a CRF-1 antagonist. Verucerfont blocks the CRH-1 receptor, and so reduces ACTH release following chronic stress. It is under investigation as a potential treatment for alcoholism. |
CSN22166 | Emicerfont | 786701-13-1 | Emicerfont is a corticotropin-releasing factor type 1 (CRF1) receptor antagonist with an IC50 of 66 nM. |
CSN33119 | Crinecerfont | 752253-39-7 | Crinecerfont is a potent, selective, and orally active corticotropin-releasing factor 1 receptor (CRF1) antagonist. |
CSN33120 | Crinecerfont hydrochloride | 321839-75-2 | Crinecerfont hydrochloride is a potent, orally active, non-peptide CRF1 receptor antagonist. |
CSN21582 | CRF, bovine | 92307-52-3 | CRF is an agonist of CRF receptor with Ki of 3.52 nM. |
CSN26622 | CP 376395 | 175140-00-8 | CP-376395 is a CRF1-selective antagonist. CRF1 receptor signaling regulates food and fluid intake in the drinking-in-the-dark model of binge alcohol consumption |
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