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CRF Receptor

货号 产品名 CAS号 信息
CSN21883 Urocortin, human 176591-49-4 Urocortin, human,is a selective agonist of endogenous CRF2 receptor, with Kis of 0.3, and 0.5 nM for rCRF2α and mCRF2β, respectively.
CSN11823 R121919 195055-03-9 R121919 is a potent small-molecule CRF1 receptor antagonist with a Ki of 2 to 5 nM for the CRF1 receptor and over 1000-fold weaker activity at the CRF2 receptor, CRF-binding protein, or 70 other receptor types.
CSN24468 Pexacerfont 459856-18-9 Pexacerfont is a potent and selective antagonist with IC50 value of 6.1nM.
CSN17561 NVS-CRF38 1207258-55-6 NVS-CRF38 is a corticotropin-releasing factor receptor 1 (CRF1) antagonist with low water solubility.
CSN21288 Verucerfont 885220-61-1 GSK561679 is a CRF-1 antagonist. Verucerfont blocks the CRH-1 receptor, and so reduces ACTH release following chronic stress. It is under investigation as a potential treatment for alcoholism.
CSN22166 Emicerfont 786701-13-1 Emicerfont is a corticotropin-releasing factor type 1 (CRF1) receptor antagonist with an IC50 of 66 nM.
CSN33119 Crinecerfont 752253-39-7 Crinecerfont is a potent, selective, and orally active corticotropin-releasing factor 1 receptor (CRF1) antagonist.
CSN33120 Crinecerfont HCl 321839-75-2 Crinecerfont hydrochloride is a potent, orally active, non-peptide CRF1 receptor antagonist.
CSN21582 CRF, bovine 92307-52-3 CRF is an agonist of CRF receptor with Ki of 3.52 nM.
CSN26622 CP 376395 175140-00-8 CP-376395 is a CRF1-selective antagonist. CRF1 receptor signaling regulates food and fluid intake in the drinking-in-the-dark model of binge alcohol consumption
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