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CXCR
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN15996 | WZ811 | 55778-02-4 | WZ811 is a small molecular and potency CXCR4 antagonist with EC50 of 0.3 nM. |
| CSN18633 | UNBS5162 | 956590-23-1 | UNBS5162 is a naphthalimide and a hydrolysis product of UNBS3157 that decreases CXCL chemokine expression in experimental prostate cancers and the mean antiproliferative activity IC50 value is 17.9 μM for 9 cancer cell lines. |
| CSN28441 | Tannic Acid | 1401-55-4 | Tannic acid is a novel hERG channel blocker with IC50 of 3.4 μM. |
| CSN17557 | SRT3190 | 1204707-73-2 | SRT3190 is CXCR2 ligand. |
| CSN17197 | SB-225002 | 182498-32-4 | SB225002 is a potent and selective non-peptide inhibitor of CXCR2 with IC50 of 22 nM, showing > 150-fold selectivity over CXCR1 and four other 7-TMRs. |
| CSN23103 | SB 332235 | 276702-15-9 | SB-332235 is a potent and specific CXCR2 antagonist. SB-332235 effectively inhibited CS-induced neutrophilia in a dose-dependent manner. |
| CSN23101 | SB 265610 | 211096-49-0 | SB-265610 is a potent CXCR2 antagonist that inhibits CINC-1-mediated but not C5a-mediated Ca2+ mobilization (IC50 values are 3.4 and 6800 nM respectively). It inhibits CINC-induced chemotaxis and attenuates neutrophil accumulation in inflammatory lung injury in vivo. |
| CSN18171 | Reparixin L-lysine | 266359-93-7 | Reparixin L-lysine is an inhibitor of CXCL8 receptor, also inhibit CXCR1 and CXCR2 activation,which has been shown to attenuate inflammatory responses in various injury models. |
| CSN15950 | Reparixin | 266359-83-5 | Reparixin is an inhibitor of CXCL8 receptor, also inhibit CXCR1 and CXCR2 activation, which has been shown to attenuate inflammatory responses in various injury models. |
| CSN12664 | Plerixafor | 110078-46-1 | Plerixafor is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively. |
| CSN16151 | Plerixafor 8HCl | 155148-31-5 | Plerixafor 8HCl is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively. |
| CSN21269 | MSX-130 | 4051-59-6 | MSX-130 is CXCR4 Antagonist. |
| CSN24505 | JMS-17-2 | 1380392-05-1 | JMS-17-2 is a potent and selective CX3CR1 antagonist with an IC50 of 0.32 nM. |
| CSN22862 | IT1t 2HCl | 1092776-63-0 | IT1t 2HCl is a potent CXCR4 antagonist with IC50 of 1.1 nM. |
| CSN22815 | FC 131 | 606968-52-9 | FC 131 is a CXCR4 antagonist with IC50 of 126 nM. |
| CSN23143 | TC 14012 | 368874-34-4 | CXCR4 antagonist; ACKR3 (CXCR7) agonist |
| CSN22780 | CTCE 9908 | 1030384-98-5 | CTCE 9908 is a CXCR4 antagonist with antitumor activity. |
| CSN18996 | BKT140 | 664334-36-5 | BKT140 is a CXCR4 antagonist with an IC50 value of ~1 nM. |
| CSN19244 | ATI-2341 | 1337878-62-2 | ATI-2341, pepducin targeting the C-X-C chemokine receptor type 4 (CXCR4), is an allosteric agonist activating the inhibitory heterotrimeric G protein (Gi) to promote inhibition of cAMP production and induce calcium mobilization. |
| CSN18287 | AMG-487 | 473719-41-4 | AMG-487 is a small molecule antagonist of the chemokine receptor CXCR3 and inhibits binding of 125I-IP-10 and 125I-ITAC to CXCR3. |
| CSN18051 | AMD 3465 | 185991-24-6 | AMD 3465 is a potent, selective CXCR4 antagonist and exhibits 8-fold higher affinity than AMD 3100 and inhibits SDF-1α-ligand binding (Ki = 41.7 nM). |
