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CXCR

CXCR

货号 产品名 CAS号 信息
CSN18633 UNBS5162 956590-23-1 UNBS5162 is a naphthalimide and a hydrolysis product of UNBS3157 that decreases CXCL chemokine expression in experimental prostate cancers and the mean antiproliferative activity IC50 value is 17.9 μM for 9 cancer cell lines.
CSN68805 Tannins 1401-55-4 Tannins (commonly referred to as tannic acid) are water-soluble polyphenols that are present in many plant foods. They have been reported to be responsible for decreases in feed intake, growth rate, feed efficiency, net metabolizable energy, and protein digestibility in experimental animals.
CSN17557 SRT3190 1204707-73-2 SRT3190 is CXCR2 ligand.
CSN17197 SB-225002 182498-32-4 SB225002 is a potent and selective non-peptide inhibitor of CXCR2 with IC50 of 22 nM, showing > 150-fold selectivity over CXCR1 and four other 7-TMRs.
CSN23103 SB 332235 276702-15-9 SB-332235 is a potent and specific CXCR2 antagonist. SB-332235 effectively inhibited CS-induced neutrophilia in a dose-dependent manner.
CSN23101 SB 265610 211096-49-0 SB-265610 is a potent CXCR2 antagonist that inhibits CINC-1-mediated but not C5a-mediated Ca2+ mobilization (IC50 values are 3.4 and 6800 nM respectively). It inhibits CINC-induced chemotaxis and attenuates neutrophil accumulation in inflammatory lung injury in vivo.
CSN18171 Reparixin L-lysine 266359-93-7 Reparixin L-lysine is an inhibitor of CXCL8 receptor, also inhibit CXCR1 and CXCR2 activation,which has been shown to attenuate inflammatory responses in various injury models.
CSN15950 Reparixin 266359-83-5 Reparixin is an inhibitor of CXCL8 receptor, also inhibit CXCR1 and CXCR2 activation, which has been shown to attenuate inflammatory responses in various injury models.
CSN21269 MSX-130 4051-59-6 MSX-130 is CXCR4 Antagonist.
CSN24505 JMS-17-2 1380392-05-1 JMS-17-2 is a potent and selective CX3CR1 antagonist with an IC50 of 0.32 nM.
CSN22862 IT1t 2HCl 1092776-63-0 IT1t 2HCl is a potent CXCR4 antagonist with IC50 of 1.1 nM.
CSN22815 FC 131 606968-52-9 FC 131 is a CXCR4 antagonist with IC50 of 126 nM.
CSN23143 TC 14012 368874-34-4 CXCR4 antagonist; ACKR3 (CXCR7) agonist
CSN32401 Burixafor 1191448-17-5 Burixafor is an orally bioavailable inhibitor of CXC chemokine receptor 4 (CXCR4) with receptor binding and hematopoietic stem cell-mobilization activities.
CSN18996 BKT140 664334-36-5 BKT140 is a CXCR4 antagonist with an IC50 value of ~1 nM.
CSN19244 ATI-2341 1337878-62-2 ATI-2341, pepducin targeting the C-X-C chemokine receptor type 4 (CXCR4), is an allosteric agonist activating the inhibitory heterotrimeric G protein (Gi) to promote inhibition of cAMP production and induce calcium mobilization.
CSN18051 AMD 3465 185991-24-6 AMD 3465 is a potent, selective CXCR4 antagonist and exhibits 8-fold higher affinity than AMD 3100 and inhibits SDF-1α-ligand binding (Ki = 41.7 nM).
CSN16529 AMD 3465 Hexahydrobromide 185991-07-5 AMD 3465 hexahydrobromide is a potent, selective CXCR4 antagonist and exhibits 8-fold higher affinity than AMD 3100 and inhibits SDF-1α-ligand binding (Ki = 41.7 nM).
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