Delta 6 desaturase (D6D or Δ-6-desaturase) is a desaturase enzyme that converts between types of fatty acids (termed 6 after omega-6 fatty acids), which are essential nutrients in the human body. The enzyme is molecularly identical across all living things (preserved across Kingdom (biology)) it is present in animals, plants, and cyanobacteria.
|CSN26132||SC-26196||218136-59-5||SC-26196 is a selective Delta 6 desaturase inhibitor with IC50 = 0.2 μM. It had pharmacokinetic and pharmacodynamic profiles in mice and showed antiinflammatory properties. It resulted in 36-37% fewer tumors in Apc(Min/+) mice and 35% decrease in primary tumor size in nude mice bearing HT-29 human colon cancer cell xenografts.|