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DGAT

DGAT

货号 产品名 CAS号 信息
CSN29469 Teglicar 250694-07-6 Teglicar (ST-1326) is a potent, selective and reversible inhibitor of liver carnitine palmitoyl-transferase 1 (L-CPT1) with IC50 of 0.68 uM, Ki of 0.36 uM.
CSN13559 PF-04620110 1109276-89-2 PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM.
CSN16959 Pradigastat 956136-95-1 LCQ-908 is a potent and oral active diacylglycerol acyltransferase 1 (DGAT1) inhibitor, used as anti-obesity and anti-diabetic agents.
CSN17613 Etomoxir 124083-20-1 Etomoxir is a cell-permeable, irreversible, and stereospecific inhibitor of carnitine palmitoyltransferase (CPT)-1 and DGAT activity in the mitochondria of rat heart H9c2 myoblastic cells at a concentration of 1-80 μM and 40 μM, respectively.
CSN33175 Ervogastat 2186700-33-2 Ervogastat is a diacylglycerol acyltransferase type 2 (DGAT-2) inhibitor.
CSN50716 N-(1-Ethyl-4,6-dimethyl-2,3-dihydro-1H-indol-7-yl)-2,2-dimethylundecanamide 288461-68-7 Diacylglycerol Acyltransferase Type 1 (DGAT-1) Inhibitors Diacylglycerol Acyltransferase Type 2 (DGAT-2) Inhibitors Sterol O-Acyltransferase 1 (SOAT1; ACAT1) Inhibitors Sterol O-Acyltransferase 2 (SOAT2; ACAT2) Inhibitors
CSN16270 DGAT1-IN-1 1449779-49-0 DGAT1-IN-1 is a potent DGAT1 inhibitor with IC50 of < 10 nM (cell lysate from Hep3B cells overexpressing human DGAT1).
CSN20207 DGAT1 Inhibitor C9 1137671-16-9 DGAT1 inhibitor C9 is an orally bioavailable benzimidazole diacylglycerol acyltransferase 1 (DGAT1) inhibitor.
CSN16487 DGAT-1 inhibitor 2 942999-61-3 DGAT-1 inhibitor 2 is an effective inhibitor of DGAT-1 and an antiobesity agent.
CSN17510 AZD7687 1166827-44-6 AZD7687 is a potent and selective DGAT1 inhibitor with an IC50 of 80 nM for hDGAT1.
CSN13687 ABT-046 1031336-60-3 ABT-046 is a potent, selective, and orally bioavailable Diacylglycerol acyltransferase 1 (DGAT-1 ) inhibitor (IC50= 8 nM).
CSN50737 N-(2-Cyanopropan-2-yl)-2-[5-[(3-ethoxypyridin-2-yl)oxy]pyridin-3-yl]pyrimidine-5-carboxamide 2186700-43-4
CSN50723 3-[3-[6-([6-[(3R)-3-(2-Ethoxyphenoxy)piperidin-1-yl]pyrazin-2-yl]amino)pyridin-2-yl]phenyl]-2,2-dimethylpropanoic acid 2659332-63-3
CSN50725 5-Chloro-N-[6-[(3R)-3-(2-ethoxyphenoxy)piperidin-1-yl]pyrazin-2-yl]-1,3-benzoxazol-2-amine 2659332-11-1
CSN50734 3-[3-(Difluoromethoxy)phenyl]-N-(1,1-dioxo-1lambda6-thiolan-3-yl)-1-(4-fluorophenyl)-1H-indole-6-carboxamide isomer A 2227100-99-2
CSN50738 2-[5-[(3-Ethoxypyridin-2-yl)oxy]pyridin-3-yl]-N-(3-methyl-1,1-dioxo-1lambda6-thiolan-3-yl)pyrimidine-5-carboxamide 2186700-36-5
CSN50747 1-[4-[(6-[[(5-Chloropyrimidin-2-yl)amino]methyl]-2-methylpyrimidin-4-yl)oxy]phenyl]-N-methylmethanesulfonamide 1781268-35-6
CSN50732 3-[5-(Difluoromethoxy)pyridin-3-yl]-1-(4-fluorophenyl)-N-(3-methyl-1,1-dioxo-1lambda6-thiolan-3-yl)-1H-indole-6-carboxamide 2227100-85-6
CSN50722 3-(3-[2-[(6-[(3R)-3-[(3-Ethoxypyridin-2-yl)oxy]piperidin-1-yl]pyrazin-2-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]phenyl)-2,2-dimethylpropanoic acid 2659333-63-6
CSN50739 1-(4-[[6-[[(5-Chloropyrimidin-2-yl)amino]methyl]-2-(trifluoromethyl)pyrimidin-4-yl]oxy]phenyl)-N-methylmethanesulfonamide 2050716-84-0
CSN50718 N-[6-[(3R)-3-(2-Ethoxyphenoxy)piperidin-1-yl]pyrazin-2-yl]-2-(4-hydroxyphenyl)acetamide 2660260-98-8
CSN50727 2-[5-[(3-Ethoxypyridin-2-yl)oxy]pyridin-3-yl]-N-[(3S,5S)-5-fluoropiperidin-3-yl]pyrimidine-5-carboxamide 2639372-47-5
CSN50726 4-[[2-([6-[(3R)-3-(2-Ethoxyphenoxy)piperidin-1-yl]pyrazin-2-yl]amino)pyrimidin-4-yl]oxy]cyclohexane-1-carboxylic acid 2659981-45-8
CSN50728 (S)-3-(2-Chloro-5-cyanophenyl)-1-(4-fluorophenyl)-N-(1-hydroxy-3-methylbutan-2-yl)-1H-indazole-6-carboxamide 2226397-42-6
CSN50730 3-(3-Cyclopropylphenyl)-1-(4-fluorophenyl)-N-(3-methyl-1,1-dioxo-1lambda6-thiolan-3-yl)-1H-indazole-6-carboxamide isomer A 2226397-64-2
CSN50736 2-(5-((3-Ethoxypyridin-2-yl)oxy)pyridin-3-yl)-N-(1-hydroxy-2-methylpropan-2-yl)pyrimidine-5-carboxamide 2186700-44-5
CSN50731 3-[3-(Difluoromethoxy)phenyl]-1-(4-fluorophenyl)-N-(3-methyl-1,1-dioxo-1lambda6-thiolan-3-yl)-1H-indazole-6-carboxamide isomer A 2226397-62-0
CSN50742 N2-tert-Butyl-N8-[2-(5-fluoro-1H-benzimidazol-2-yl)ethyl]-5-[3-(trifluoromethyl)phenyl]-3,4-dihydroisoquinoline-2,8(1H)-dicarboxamide 1884333-62-3
CSN50744 Methyl 3-[2-(tert-butylcarbamoyl)-8-[([1-[4-(trifluoromethyl)phenyl]piperidine-4-carbonyl]amino)methyl]-1,2,3,4-tetrahydroisoquinolin-5-yl]benzoate 1884333-55-4
CSN50729 3-(2-Chloro-5-cyanophenyl)-1-(4-fluorophenyl)-N-(3-methyl-1,1-dioxo-1lambda6-thiolan-3-yl)-1H-indazole-6-carboxamide isomer A 2226398-28-1
CSN50743 N2-tert-Butyl-N8-[2-(5,6-dichloro-1H-benzimidazol-2-yl)ethyl]-5-[3-(trifluoromethyl)phenyl]-3,4-dihydroisoquinoline-2,8(1H)-dicarboxamide 1884333-61-2
CSN50750 1-[2-(Benzyloxy)benzyl]-5-methyl-1H-indole-2,3-dione 620931-38-6
CSN50741 N2-tert-Butyl-N8-[2-(5-chloro-1H-benzimidazol-2-yl)ethyl]-5-[3-(trifluoromethyl)phenyl]-3,4-dihydroisoquinoline-2,8(1H)-dicarboxamide 1884333-60-1
CSN50712 (-)-[(3R)-1-[2-[(1S)-1-(4-Chloro-1H-pyrazol-1-yl)ethyl]-1H-imidazo[4,5-b]pyridin-5-yl]piperidin-3-yl](pyrrolidin-1-yl)methanone hydrogen chloride 1469285-69-5
CSN50719 N-[6-[(3R)-3-(2-Ethoxyphenoxy)piperidin-1-yl]pyrazin-2-yl]-1-(propane-2-sulfonyl)piperidine-4-carboxamide 2660260-79-5
CSN50735 2-[5-[(3-Ethoxy-5-fluoropyridin-2-yl)oxy]pyridin-3-yl]-N-[(3S)-oxolan-3-yl]pyrimidine-5-carboxamide 2186700-48-9
CSN50713 N-tert-Butyl-5-(3-methoxyphenyl)-8-[([[trans-2-phenylcyclopropyl]carbonyl]amino)methyl]-3,4-dihydroisoquinoline-2(1H)-carboxamide 1825360-70-0
CSN50733 3-[3-(Difluoromethoxy)phenyl]-N-(1,1-dioxo-1lambda6-thiolan-3-yl)-1-(5-fluoropyrimidin-2-yl)-1H-indole-6-carboxamide isomer A 2227100-79-8
CSN50746 3-[(1R)-1-[([2-[(3R)-3-(2-Ethoxyphenoxy)piperidin-1-yl]pyrimidin-5-yl]carbonyl)amino]ethyl]benzoic acid 1809064-25-2
CSN50724 2-[4-[6-([6-[(3R)-3-(2-Ethoxyphenoxy)piperidin-1-yl]pyrazin-2-yl]amino)pyridin-2-yl]phenyl]-2-methylpropanoic acid 2659332-61-1
CSN50720 N-[6-[(3R)-3-(2-Ethoxyphenoxy)piperidin-1-yl]pyrazin-2-yl]-4-nitrobenzamide 2660260-72-8
CSN50748 1-[4-[(6-[[(5-Chloropyrimidin-2-yl)amino]methyl]-2-methylpyrimidin-4-yl)oxy]phenyl]methanesulfonamide 1781268-36-7
CSN50749 [(3R)-1-[8-[1-(4-Chloro-1H-pyrazol-1-yl)cyclopropyl]-9H-purin-2-yl]piperidin-3-yl](pyrrolidin-1-yl)methanone 1469284-77-2
CSN50715 [(3R)-1-[2-(2-Cyclopropylpyrimidin-4-yl)-3H-imidazo[4,5-b]pyridin-5-yl]piperidin-3-yl](pyrrolidin-1-yl)methanone 1469284-64-7
CSN50740 1-[4-[(4-[[(5-Ethylpyrimidin-2-yl)amino]methyl]pyridin-2-yl)oxy]-3-fluorophenyl]methanesulfonamide 2050716-75-9
CSN50745 Methyl 3-[8-[([1-[4-(trifluoromethyl)phenyl]piperidine-4-carbonyl]amino)methyl]isoquinolin-5-yl]benzoate 1884334-37-5
CSN50721 N-[6-[(3R)-3-(2-Ethoxyphenoxy)piperidin-1-yl]pyrazin-2-yl]-1-(5-ethylpyrimidin-2-yl)piperidine-4-carboxamide 2660260-80-8
CSN50717 3-[4-(2-Amino-2-oxoethyl)phenyl]-N-[6-[(3R)-3-(2-ethoxyphenoxy)piperidin-1-yl]pyrazin-2-yl]propanamide 2660261-12-9
CSN50714 N-tert-Butyl-5-(3-methoxyphenyl)-8-[([[(1S,2S)-2-(3-methyl-1,2,4-oxadiazol-5-yl)cyclopropyl]carbonyl]amino)methyl]-3,4-dihydroisoquinoline-2(1H)-carboxamide 1825360-71-1
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