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DNA/RNA Synthesis
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN24863 | Uridine 5'-monophosphate | 58-97-9 | Uridine 5'-monophosphate is a nucleotide that is used as a monomer in RNA. |
| CSN16447 | Uracil | 66-22-8 | Uracil is one of the four nucleobases in the nucleic acid of RNA can be used for drug delivery and as a pharmaceutical. |
| CSN12504 | Tranexamic acid | 1197-18-8 | Tranexamic acid is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM. |
| CSN19417 | 4-(Aminomethyl)cyclohexanecarboxylic acid | 701-54-2 | Tranexamic Acid (Random Configuration) is a medication used to treat or prevent excessive blood loss from major trauma, surgery, tooth removal, nose bleeds, and heavy menstruation.Inducing single-and double-strand breaks in DNA, base damage, and cell death. |
| CSN43681 | TK216 | 1903783-48-1 | TK-216, an analog of YK-4-279 inhibitor, is a potent and selective EWS-FLI1 inhibitor. TK-216 is in early clinical development for the treatment of Ewing sarcoma. |
| CSN21982 | Tetrahydrouridine | 18771-50-1 | Tetrahydrouridine is potent inhibitor of cytidine deaminase (CDA). |
| CSN51391 | FEN1-IN-SC13 | 2098776-03-3 | SC13 specifically inhibits FEN1 activity. It suppresses cancer cell proliferation and induces chromosome instability and cytotoxicity in cells, as well as sensitizes cancer cells to DNA damage-inducing therapeutic modalities and impedes cancer progression in a mouse model. |
| CSN32990 | RRM1 Inhibitor 1 | 2563874-93-9 | Ribonucleoside-Diphosphate Reductase Large Subunit (RRM1) Inhibitors;TNF-alpha (ARE sequence)/ELAV-Like protein 1 (HuR) Interaction Inhibitors |
| CSN32991 | RRM1 Inhibitor 2 | 2247176-87-8 | Ribonucleoside-Diphosphate Reductase Large Subunit (RRM1) Inhibitors |
| CSN32994 | RRM1 Inhibitor 5 | 1271734-91-8 | Ribonucleoside-Diphosphate Reductase Large Subunit (RRM1) Inhibitors |
| CSN32992 | RRM1 Inhibitor 3 | 1819992-33-0 | Ribonucleoside-Diphosphate Reductase Large Subunit (RRM1) Inhibitors |
| CSN26441 | RG7800 | 1449598-06-4 | RG7800 HCl is an orally active SMN2 splicing modulator, with EC1.5xs of 23 nM and 87 nM for SMN2 splicing and SMN protein; has the potential to treat spinal muscular atrophy. |
| CSN17016 | Resveratrol | 501-36-0 | Resveratrol is one of the numerous polyphenolic compounds found in several vegetal sources, has a wide spectrum of targets with IC50 of 0.8, 1, 3.3 and 5 μM for Adenylyl cyclase, IKKβ, DNA polymerase α and δ, respectively. |
| CSN11829 | Raltitrexed | 112887-68-0 | Raltitrexed is an inhibitor of thymidylate synthase with IC50 of 9 nM in L1210 cell. |
| CSN16448 | Psoralen | 66-97-7 | Psoralen, an ingredient from Fructus Psoraleae, intercalates with DNA, inhibiting DNA synthesis and cell division and showing anticancer activity. |
| CSN21764 | Nitracrine | 4533-39-5 | Nitracrine, an acridine antineoplastic used in ovarian tumors, can inhibit RNA synthesis. |
| CSN25485 | N2,N2-Dimethylguanosine | 2140-67-2 | N,N-Dimethylguanosine, an urinary nucleoside, is a primary degradation product of tRNA. |
| CSN19748 | MS-444 | 150045-18-4 | MS-444 is a chrysanthone-like compound specifically inhibit the HuR from binding ARE-RNAs. |
| CSN43591 | Metarrestin | 1443414-10-5 | Metarrestin is a specific inhibitor of perinuclear compartment (PNC). |
| CSN22455 | LysRs-IN-1 | 281676-77-5 | LysRs-IN-1 is a Lysyl-tRNA synthetase (LysRs) inhibitor. |
| CSN33100 | Indisulam analog 4 | 444579-59-3 | Indisulam analog 4, as molecular glue, is especially effective and improves the half maximal effective concentration (EC50) to 1.21 µM in recruiting RBM39 to the DCAF15–DDB1–DDA1 complex. |
| CSN26246 | HAMNO | 138736-73-9 | HAMNO is a potent and selective inhibitor of replication protein A (RPA) interactions with proteins involved in the replication stress response. It has shown to significantly inhibits colony formation when combined with etoposide. |
| CSN23239 | Guanosine | 118-00-3 | Guanosine is a purine nucleoside. |
| CSN29504 | Gemcitabine monophosphate | 116371-67-6 | Gemcitabine is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively. |
| CSN22052 | Deoxypseudouridine | 39967-60-7 | Deoxypseudouridine is a nucleotide analog. |
| CSN16684 | Daptomycin | 103060-53-3 | Daptomycin is a lipopeptide antimicrobial agent with activity against Gram-positive organisms, including multi-resistant strains. |
| CSN24877 | Cytidine-5'-triphosphate disodium | 36051-68-0 | Cytidine 5'-triphosphate is a pyrimidine nucleoside triphosphate that is involved in a variety of biochemical reactions. It is used in the synthesis of RNA by RNA polymerases. |
| CSN25243 | CMLD-2 | 958843-91-9 | CMLD-2 competitively binds to Hu antigen R with Ki value of 350nM and disrupts the interaction of HuR and ARE (adenine- and uridine-rich element) of target mRNAs. |
| CSN27392 | AV-153 free base | 19350-66-4 | AV-153 free base, a 1,4-dihydropyridine (1,4-DHP) derivative, is an antimutagenic. AV-153 free base intercalates to DNA in a single strand break and reduces DNA damage, stimulates DNA repair in human cells in vitro. AV-153 free base interacts with thymine and cytosine and has an influence on poly(ADP)ribosylation. AV-153 free base has anti-cancer activity. |
| CSN32946 | COH-4 | 1190932-36-5 | Apoptosis Inducers; RRM2 Expression Inhibitors |
| CSN32948 | COH-20 | 1190932-37-6 | Apoptosis Inducers; RRM2 Expression Inhibitors |
| CSN32947 | COH-2 | 20217-22-5 | Apoptosis Inducers; RRM2 Expression Inhibitors |
| CSN18264 | A2AR-agonist-1 | 41552-95-8 | A2AR-agonist-1 is a potent A2AR and ENT1 agonist with Ki of 4.39 and 3.47 for A2AR and ENT1. |
| CSN23866 | (2R,3R,4S,5R)-2-(6-Amino-8-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | 34408-14-5 | 8-Chloroadenosine is a cytotoxic nucleoside analog, it can inhibit RNA synthesis. |
| CSN25518 | 6-Thioguanosine | 85-31-4 | 6-thioguanosine is photosensitive molecule that photocrosslinks to both proteins and nucleic acids. |
| CSN12836 | 6-Mercaptopurine hydrate | 6112-76-1 | 6-Mercaptopurine Monohydrate inhibits the de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA, it is a widely used antileukemic agent and immunosuppressive drug. 6-mercaptopurine was found to inhibit SARS-CoV PLpro. |
| CSN16373 | 6-Mercaptopurine | 50-44-2 | 6-Mercaptopurine inhibits the de novo purine synthesis through interference with DNA and RNA synthesis, it's an immunosuppressive and antileukemic drug. 6-mercaptopurine was found to inhibit SARS-CoV PLpro. |
| CSN24938 | 5-Methylcytosine | 554-01-8 | 5-Methylcytosine, a methylated form of the DNA base cytosine, is a major epigenetic mark in the nuclear DNA in mammals and may be involved in the regulation of gene transcription. |
| CSN24883 | 5-Methyl-2'-deoxycytidine | 838-07-3 | 5-Methyl-2'-deoxycytidine (5-Me-dC) is a minor component found in most eukaryotic DNA. |
| CSN25531 | 4-Amino-5-bromo-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one | 3066-86-2 | 5-Bromocytidine is a bromine substituted nucleoside.Its β-isomer derivative is a potent anti-HIV agent. |
| CSN27391 | 3,4-Dihydroxybenzylamine hydrobromide | 16290-26-9 | 3,4-Dihydroxybenzylamine hydrobromide (NSC 263475 hydrobromide) is an improved dopamine analog cytotoxic and inhibits DNA polymerase activity in melanoma cells. 3,4-Dihydroxybenzylamine hydrobromide (NSC 263475 hydrobromide) displays growth inhibitory activity in melanoma cell lines with varying degrees of tyrosinase activity. |
| CSN18758 | 2'-Deoxycytidine hydrochloride | 3992-42-5 | 2'-Deoxyguanosine HCl is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose. |
| CSN25519 | 8-Mercaptoadenosine | 3001-45-4 | |
| CSN27830 | NSAH | 1099592-35-4 | |
| CSN32745 | SCR130 | 2377858-38-1 | |
| CSN62426 | Nusinersen | 1258984-36-9 | |
| CSN63477 | NVS-SM2 | 1562333-92-9 | |
| CSN85479 | Branaplam hydrochloride | 1562338-39-9 | |
| CSN107520 | N,3,4,5-Tetrahydroxybenzimidamide | 95933-74-7 |
