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Epigenetic Reader Domain
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN22252 | KG-501 | 18228-17-6 | KG-501 is histochemical substrate of alkaline phosphatases and can inhibit CREB-CBP interaction. |
| CSN18953 | GSK6853 | 1910124-24-1 | GSK6853 selectively inhibits the BRPF1 bromodomain with the pKd value of 9.5. |
| CSN22363 | C-82 | 1422253-37-9 | C-82 is an active metabolite of PRI-724 which selectively inhibits the CBP/β-catenin interaction. |
| CSN18952 | BI-9564 | 1883429-22-8 | BI-9564 is an inhibitor of BRD9 (IC50 = 75 nM) and BRD7 (IC50 = 3.4 µM). |
| CSN18046 | ARV-825 | 1818885-28-7 | ARV-825 is a PROTAC targeting on BRD4, consisting of a BRD4-ligand JQ-1 linked to a cereblon E3 ligase ligand Pomalidomide, with Kds values of 90nM and 28nM for affinity to BD1 and BD2. |
| CSN24157 | 666-15 | 1433286-70-4 | 666-15 is a potent and cell-permeable inhibitor of cAMP-response element binding protein (CREB) with efficacious anti-cancer activity both in vitro and in vivo. |
| CSN18086 | JQ-1 Carboxylic Acid | 202592-23-2 | (+)-JQ1 carboxylic acid is a warhead ligand with a carboxylic acid functional group for conjugation reactions of PROTAC targeting on BET. |