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Factor Xa

Factor Xa

货号 产品名 CAS号 信息
CSN26500 Razaxaban HCl 405940-76-3 Razaxaban, also known as BMS-561389; BMS-561389-01; DPC-906; BMS-561389-06, is a factor Xa inhibitor potentially for the treatment of thrombosis. Razaxaban was an effective antithrombotic agent in a rabbit model of arterial thrombosis. Low-dose razaxaban was useful in combination with sub-optimal doses of aspirin and/or clopidogrel for the prevention of occlusive arterial thrombosis without excessive bleeding.
CSN18070 Otamixaban 193153-04-7 Otamixaban is a potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa.
CSN12447 Fondaparinux Sodium   114870-03-0 Fondaparinux sodium is a pentasaccharide inhibitor of antithrombin-dependent factor Xa (IC50 = 40 nM). It can bind to antithrombin III.
CSN28842 Darexaban 365462-23-3 Darexaban is a potent and orally effective factor Xa inhibitor with IC50 value of 54.6nM.
CSN12369 Betrixaban 330942-05-7 Betrixaban is a highly potent, selective, and orally efficacious factor Xa inhibitor with IC50 of 1.2 nM (inhibition of Factor 10a).
CSN12320 Apixaban 503612-47-3 Apixaban is a direct factor Xa inhibitor with an IC50 of 0.08 nM and 0.17 nM in human and rabbit, respectively.
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