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Factor Xa
货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN12263 | Rivaroxaban | 366789-02-8 | Rivaroxaban is an inhibitor of factor Xa (FXa) with IC50 of 0.7 nM and Ki of 0.4 nM which developed for the treatment of thrombotic disease. |
CSN26500 | Razaxaban hydrochloride | 405940-76-3 | Razaxaban, also known as BMS-561389; BMS-561389-01; DPC-906; BMS-561389-06, is a factor Xa inhibitor potentially for the treatment of thrombosis. Razaxaban was an effective antithrombotic agent in a rabbit model of arterial thrombosis. Low-dose razaxaban was useful in combination with sub-optimal doses of aspirin and/or clopidogrel for the prevention of occlusive arterial thrombosis without excessive bleeding. |
CSN18070 | Otamixaban | 193153-04-7 | Otamixaban is a potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa. |
CSN12447 | Fondaparinux sodium | 114870-03-0 | Fondaparinux sodium is a pentasaccharide inhibitor of antithrombin-dependent factor Xa (IC50 = 40 nM). It can bind to antithrombin III. |
CSN15688 | Edoxaban tosylate monohydrate | 1229194-11-9 | Edoxaban tosylate is a selective factor Xa inhibitor with Ki of 0.561 nM, > 10 000-fold selectivity over thrombin and FIXa, and is also an orally bioavailable anticoagulant drug. |
CSN13691 | Edoxaban tosylate | 480449-71-6 | Edoxaban is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention. |
CSN12900 | Edoxaban | 480449-70-5 | Edoxaban is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention. |
CSN28842 | Darexaban | 365462-23-3 | Darexaban is a potent and orally effective factor Xa inhibitor with IC50 value of 54.6nM. |
CSN12369 | Betrixaban | 330942-05-7 | Betrixaban is a highly potent, selective, and orally efficacious factor Xa inhibitor with IC50 of 1.2 nM (inhibition of Factor 10a). |
CSN12320 | Apixaban | 503612-47-3 | Apixaban is a direct factor Xa inhibitor with an IC50 of 0.08 nM and 0.17 nM in human and rabbit, respectively. |
CSN18499 | 5-R-Rivaroxaban | 865479-71-6 | 5-R-Rivaroxaban is an (R) enantiomer of rivaroxaban, an oral, direct Factor Xa (FXa) inhibitor in late-stage development for the prevention and treatment of thromboembolic disorders. |