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FAK

FAK

货号 产品名 CAS号 信息
CSN17077 Y15 4506-66-5 Y15 is a small molecule FAK phosphorylation inhibitor which specifically block phosphorylation of Y397-FAK and total phosphorylation of FAK.
CSN20842 Solanesol 13190-97-1 Solanesol is a C45 isoprenoid alcohol, it is the most abundant lipid in tobacco leaves and may be an important precursor of the tumorigenic polynuclear aromatic hydrocarbons of smoke.
CSN16593 PND-1186 1061353-68-1 PND-1186 is a potent FAK inhibitor with IC50 of 1.5 nM.
CSN16483 PF-573228 869288-64-2 PF-573228 is a potent and selective FAK inhibitor with IC50 of 4 nM for inhibiton of purified recombinant catalytic fragment of FAK and inhibits FAK phosphorylation on Tyr(397) with an IC(50) of 30-100 nM.
CSN13737 PF-562271 Besylate 939791-38-5 PF-562271 besylate is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and > 100-fold selectivity against other protein kinases, except for some CDKs.
CSN16907 CEP-37440 1391712-60-9 CEP-37440 is a potent and selective Dual FAK/ALK inhibitor with IC50 s of 2.3 nM (FAK) and 120 nM (ALK cellular IC50 in 75% human plasma).
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