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FAS
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN43342 | TVB-3166 | 1533438-83-3 | TVB-3166 is an orally-available, reversible, potent, and selective FASN inhibitor. |
| CSN12770 | Isoniazid | 54-85-3 | Isonicotinic acid hydrazide is an antibacterial agent used primarily as a tuberculostatic by blocking the action of fatty acid synthase by interacting with KatG. |
| CSN22569 | HS80 | 2138838-57-8 | HS-80 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-80 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 7.13 μM. |
| CSN22568 | HS79 | 2138838-56-7 | HS-79 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-79 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 1.57 μM. |
| CSN24078 | FT113 | 1630808-89-7 | FT113 is a potent and orally active fatty acid synthase (FASN) inhibitor, with an IC50 of 213 nM for full-length recombinant human FASN enzyme. |
| CSN19046 | FAS-IN-1 Tosylate | 2095432-57-6 | FAS-IN-1 tosylate is a potent inhibitor of fatty acid synthase (FAS) with an IC50 of 10 nM. |
| CSN17761 | FASN-IN-4 | 1375105-96-6 | FAS-IN-1 is a potent inhibitor of Fatty acid synthase (FAS) wtih IC50 of 10 nM. |
| CSN19341 | Desoxyrhaponticin | 30197-14-9 | Desoxyrhaponticin, a natural product isolated and purified from the roots of Rumex obtusifolius L., is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least, by inhibition of glucose transport in the small intestine and inhibition of glucose reabsorption in the kidney, and is considered as promising fatty acid synthase(FAS) inhibitors, they could inhibit intracellular FAS activity and downregulate FAS expression in human breast cancer MCF-7 cells. |
| CSN10522 | trans-C75 | 191282-48-1 | C75 trans is the trans form of C75, which is a potent fatty-acid synthase (FASN) inhibitor with IC50 of 35.4 μM (LNCaP cell Proliferation inhibition). According to the reporter, C75 is a racemic mixture of cis and trans C75 isomers. However, for cis isomer is less soluble in aqueous solutions and the trans isomer of C75 was soluble in culture media, the trans isomer of C75 shows more activity. |
| CSN19370 | C75 | 218137-86-1 | C75 is a potent fatty-acid synthase (FASN) inhibitor with IC50 of 35.4 μM (LNCaP cell Proliferation inhibition). |
| CSN20801 | Ac-CoA Synthase Inhibitor1 | 508186-14-9 | Ac-CoA Synthase Inhibitor is a reversible inhibitor of acetate-dependent acetyl-CoA synthetase 2 (ACSS2) with IC50 of ~ 600 nM. |
| CSN93080 | (6R,16R)-10,12-Dichloro-11,13,15-trihydroxy-3-methoxy-1,6,9,9-tetramethyl-6,7,9,16-tetrahydro-14H-6,16-epoxyanthra[2,3-e]benzo[b]oxocin-14-one | 866022-28-8 |
