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FAS

FAS

货号 产品名 CAS号 信息
CSN12770 Isonicotinic Acid Hydrazide 54-85-3 Isonicotinic acid hydrazide is an antibacterial agent used primarily as a tuberculostatic by blocking the action of fatty acid synthase by interacting with KatG.
CSN17761 FAS-IN-1 1375105-96-6 FAS-IN-1 is a potent inhibitor of Fatty acid synthase (FAS) wtih IC50 of 10 nM.
CSN19341 Desoxyrhaponticin 30197-14-9 Desoxyrhaponticin, a natural product isolated and purified from the roots of Rumex obtusifolius L., is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least, by inhibition of glucose transport in the small intestine and inhibition of glucose reabsorption in the kidney, and is considered as promising fatty acid synthase(FAS) inhibitors, they could inhibit intracellular FAS activity and downregulate FAS expression in human breast cancer MCF-7 cells.
CSN10522 C75 191282-48-1 C75 trans is the trans form of C75, which is a potent fatty-acid synthase (FASN) inhibitor with IC50 of 35.4 μM (LNCaP cell Proliferation inhibition). According to the reporter, C75 is a racemic mixture of cis and trans C75 isomers. However, for cis isomer is less soluble in aqueous solutions and the trans isomer of C75 was soluble in culture media, the trans isomer of C75 shows more activity.
CSN19370 C75 218137-86-1 C75 is a potent fatty-acid synthase (FASN) inhibitor with IC50 of 35.4 μM (LNCaP cell Proliferation inhibition).
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